Digestive Health What Is Acute Appendicitis? By Michelle Pugle Michelle Pugle Facebook LinkedIn Twitter Michelle Pugle is an expert health writer with nearly a decade of experience contributing accurate and accessible health information to authority publications. Learn about our editorial process Published on January 31, 2023 Medically reviewed by Keri Peterson, MD Medically reviewed by Keri Peterson, MD Facebook LinkedIn Twitter Keri Peterson, MD, is board-certified in internal medicine and has her own private practice on the Upper East Side of Manhattan. She holds appointments at Lenox Hill Hospital and Mount Sinai Medical Center. Learn about our Medical Expert Board Print Yurii Yarema / Getty Images Table of Contents View All Table of Contents Acute vs. Chronic Symptoms Causes How Serious Is It? Diagnosis & Treatment Complications Acute Appendicitis and Pregnancy Appendicitis vs. Acute Appendicitis Outlook Acute means sudden (i.e., sudden onset of symptoms). The causes of acute appendicitis are said to involve factors causing a blockage. This blockage creates bacteria collection in the appendix, resulting in inflammation, infection, and/or severe pain in your lower right abdomen area. Untreated, acute appendicitis can cause the appendix to burst or rupture, causing bacteria to spill into your bloodstream, which can cause sepsis and even death. For this reason, acute appendicitis should always be treated as a medical emergency. Read on to learn the difference between acute appendicitis and chronic appendicitis, including symptoms of acute appendicitis to watch for in adults and children, what causes appendicitis, how to get a diagnosis and treatment for appendicitis, the link between pregnancy and appendicitis, and what to expect in terms of recovery from appendicitis. What Does the Appendix Do? Acute Appendicitis vs. Chronic Appendicitis Acute appendicitis is the sudden onset of appendicitis. It comes on quickly, progresses to an emergency quickly, and is cause for immediate medical care. Acute appendicitis is cited as the most common abdominal surgical emergency in the world, with an annual incidence of 96.5 to 100 cases per 100,000 adults or 1 in 1,000 adults. Chronic appendicitis symptoms of abdominal pain are the same but are said to be milder than acute appendicitis. These symptoms can come and go over weeks, months, and years. Although chronic appendicitis is not seen as an immediate medical emergency, it’s important to see your healthcare provider about abdominal pain as it can lead to acute appendicitis. Primary and Secondary Chronic Pain Classifications Acute Appendicitis Symptoms The most common symptom of acute appendicitis is abdominal pain in the lower right abdomen area where your appendix is located. Symptoms tend to come on quickly and worsen quickly, too. Symptoms in Adults vs. Children It was previously thought that classic symptoms of acute appendicitis were less present in cases of appendicitis in children than in adults and that children generally had a delayed presentation of symptoms compared to adults. One study examined symptoms in 210 children and 744 adults and found that contrary to traditional teaching, diagnosing acute appendicitis in children and adults is more similar than not. Specifically, researchers didn’t find delayed presentation of symptoms in children. Common symptoms of acute appendicitis and burst appendix include: Abdominal pain that worsens when you breathe, move, sneeze, or cough Swollen abdomen (particularly the lower right side which is tender to the touch) Constipation or diarrhea Additional digestive discomfort from not being able to pass gas Loss of appetite Nausea or vomiting Low-grade fever or fever between 100° F to 101° F (37.7° C to 38.3° C) Causes of Appendix Pain and Treatment Options What Causes Acute Appendicitis Acute appendicitis is caused by a blockage inside it or outside it between the appendix and the large intestine. Inside the appendix, blockages can be caused by bacteria, viruses, or parasites like intestinal worms. Outside the appendix, the blockage can be caused by hard stools (severe constipation) or tumor growth. Blockage can begin to cut off blood flow to the appendix; without treatment, it can burst or lose all functionality (i.e., die). If acute appendicitis leads to rupture, stool, mucus, and infection can spread to the bloodstream. Risk of a serious infection known as peritonitis increases. How Common Is Acute Appendicitis? Specifically in the US, acute appendicitis carries a lifetime risk of 8.6% in males and 6.7% in females. How Serious Is Acute Appendicitis? Acute appendicitis is always a serious and immediate medical emergency and should be responded to as such. Someone with acute appendicitis is at risk of their appendix bursting, leading to serious infection, health complications, and even death. With acute appendicitis, the appendix can rupture or tear within as little as 48 to 72 hours after you first experience symptoms. This is why seeking immediate care from your healthcare provider or emergency department is critical. Diagnosis & Treatment of Acute Appendicitis The sudden onset of severe abdominal pain (the kind that wakes you from sleep) is a telltale sign to see a healthcare provider for an accurate diagnosis. Acute appendicitis is diagnosed based on a: Physical exam, which includes pressing on the lower right side of your abdomen to test for your reactionHealth history involving questions about any previous abdominal pains or digestive disordersBasic blood panel to test for infection C-reactive protein blood test to check for other causes of inflammationUrine test analysis to test for infection or pregnancy Additionally, your healthcare provider may request the following further diagnostic tests: Abdominal ultrasound to check for noticeable blockage and how blood is flowing Computerized tomography (CT) scan to check surrounding bones, muscles, fats, and organs Magnetic resonance imaging (MRI) scan instead of CT if you have a pregnancy Treatment of acute appendicitis typically requires surgically removing the appendix (i.e., an appendectomy). This remains the same whether or not your appendix bursts. The surgeons will remove your appendix anyways to prevent future cases of appendicitis. Complications The main complication from acute appendicitis is a ruptured or burst appendix. If your appendix bursts, it opens a path for infection to spread. Other complications include: Abscess or pus-filled pockets resulting from infection Sepsis if bacteria gets into bloodstream Peritonitis (severe abdominal infection) Both sepsis and peritonitis are serious medical emergencies that can result in death if not treated promptly. There is no known way to prevent acute appendicitis or appendix rupture, but getting to the emergency room as soon as you detect symptoms is the best way to help reduce the risk of complications associated with acute appendicitis. Acute Appendicitis and Pregnancy Acute appendicitis is the most common surgical problem experienced in pregnancy. The diagnosis, though, is complicated by pregnancy symptoms which cause abdominal and digestive discomfort. It’s also been suggested that pregnant persons experience less pain from acute appendicitis, and the area is less tender than in other people. Delayed diagnosis may be behind the high incidence of burst appendixes in the third trimester in this population. If you are pregnant and experiencing abdominal pain, be sure not to assume the symptoms are associated and seek medical attention. What Is a Pregnant Belly? What Is the Difference Between Appendicitis and Acute Appendicitis? The main difference between appendicitis and acute appendicitis is the onset time of symptoms. When experiencing any acute form of an illness, the symptoms will come on quickly and intensely. You won’t be able to ignore the pain as a nagging or discomforting sensation; it will be unlike other abdominal pains. Appendicitis typically refers to chronic appendicitis or appendicitis that is milder but with ongoing and fluctuating symptoms that can progress to acute appendicitis and medical emergencies. The Difference Between Chronic and Acute Conditions Outlook The outlook for people with acute appendicitis who seek immediate medical care is excellent. You can live a healthy life without your appendix. If your appendix bursts, though, recovering from acute appendicitis will take a little longer, and treating for potential infection with antibiotics may be necessary. Abdominal Pain: When Should I See a Healthcare Provider? Summary Acute appendicitis is a sudden onset of severe abdominal pain and symptoms of infection caused by a blockage. The appendix may be blocked by bacteria, viruses, or parasites or be obstructed by stool, or, less likely, a tumor. Acute appendicitis is always a medical emergency because it progresses quickly and can lead to appendix rupture. If your appendix bursts, it can cause serious infections and be fatal. Therefore, immediate treatment, which involves surgical removal of the appendix, and may include antibiotic treatment to remedy or prevent infection, is critical to avoid complications. 9 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Johns Hopkins Medicine. Appendicitis. Moris D, Paulson EK, Pappas TN. Diagnosis and management of acute appendicitis in adults: a review. JAMA. 2021;326(22):2299–2311. doi:10.1001/jama.2021.20502 Kothadia JP, Katz S, Ginzburg L. Chronic appendicitis: uncommon cause of chronic abdominal pain. Therapeutic Advances in Gastroenterology. 2015;8(3):160-162. doi:10.1177/1756283X15576438 Jacobs DO. Acute appendicitis and peritonitis. Kasper D, Fauci A, Hauser S, Longo D, Jameson J, Loscalzo J (Eds.), Harrison's Principles of Internal Medicine, 19e. McGraw Hill. 2014. Lee SL, Ho HS. Acute appendicitis: is there a difference between children and adults? Am Surg. 2006;72(5):409-413. doi:10.1177/000313480607200509 Snyder MJ, Guthrie M, Cagle S. Acute appendicitis: efficient diagnosis and management. Am Fam Physician. 2018;98(1):25-33. Johns Hopkins Medicine. Appendicitis. NIDDK. Appendicitis. Journal of the American Board of Family Medicine. Appendicitis in pregnancy. By Michelle Pugle Michelle Pugle, BA, MA, is an expert health writer with nearly a decade of contributing accurate and accessible health news and information to authority websites and print magazines. Her work focuses on lifestyle management, chronic illness, and mental health. Michelle is the author of Ana, Mia & Me: A Memoir From an Anorexic Teen Mind. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit