Orthopedics Osteoporosis Understanding Anxiety and Osteoporosis By Brandi Jones, MSN-ED RN-BC Brandi Jones, MSN-ED RN-BC Brandi Jones MSN-Ed, RN-BC is a board-certified registered nurse who owns Brandi Jones LLC, where she writes health and wellness blogs, articles, and education. She lives with her husband and springer spaniel and enjoys camping and tapping into her creativity in her downtime. Learn about our editorial process Published on December 06, 2022 Medically reviewed by David Ozeri, MD Medically reviewed by David Ozeri, MD LinkedIn David Ozeri, MD, is a board-certified rheumatologist from Tel Aviv, Israel specializing in arthritis, autoimmune diseases, and biologic therapies. Learn about our Medical Expert Board Print Table of Contents View All Table of Contents Anxiety and Osteoporosis Complications Diagnosis Treatment How to Cope Though anxiety and osteoporosis are two different diseases, having both conditions is common. This article reviews each disease, how they impact each other, complications, diagnosis, treatment, and coping. AsiaVision / Getty Images The Prevalence of Anxiety and Osteoporosis Approximately 31% of U.S. adults have anxiety symptoms. About 10 million people over the age of 50 have osteoporosis in the United States.Worldwide, one fracture from osteoporosis occurs every three seconds. Osteoporotic fractures are three times more likely in those assigned female at birth than those assigned male. Osteoporosis Facts and Statistics: What You Need to Know The Connection Between Anxiety and Osteoporosis The connection between anxiety and osteoporosis may seem unlikely, but they affect each other. The following is an overview of each disease and the relationship between the two. Anxiety "Fight or flight" is the body's natural response to danger or stressors. It activates the nervous system, telling it to make extra epinephrine (adrenaline). This prepares the body by increasing the heart rate, breathing rate, blood pressure, and blood sugar. Extra adrenaline can cause worry, dread, and physical symptoms such as nausea or shakiness. Anxiety disorder (AD) occurs when this stress reaction lingers or is out of proportion. AD is one of the most prevalent mental disorders and is frequently linked to depression, phobias, and panic attacks. Panic Attack Symptoms Many of those with anxiety also have panic attacks, which can cause:A racing heartSweatingShaking Chest pain Out-of-control feelingsAn impending sense of doom Osteoporosis Osteoporosis causes bone thinning and deterioration. Bones have a honeycomb-type structure that allows bones to be strong yet lightweight. Osteoporosis decreases bone mass, leaving larger structural gaps and making bones more fragile. Symptoms of osteoporosis include: Losing heightStooping forward Back painShortness of breath Bone fractures (from minor force) Though this is not a complete list, risk factors for osteoporosis include the following: AgingSmokingFemale sex Inactivity Certain medications and medical conditions How Anxiety Affects Osteoporosis Chronic anxiety produces long-term physical, emotional, and behavioral changes. It can worsen chronic health conditions and disrupt the endocrine, nervous, and immune systems, leading to poor bone health. How Osteoporosis Affects Anxiety Osteoporosis causes physical limitations. This may force someone to make unwanted lifestyle changes and can cause anxiety due to: Less physical activityFear of falling and fracturesDepressionSelf-esteem issuesFinancial problems Complications of Anxiety and Osteoporosis Complications of anxiety involve depression, substance abuse, insomnia, and isolation. Osteoporosis can lead to fractures and increased difficulty in healing from fractures. Shared Risk Factors Anxiety and osteoporosis share risk factors that increase the risk of complications, including: Altered nutrition Cigarette smoking Excessive alcohol use Physical inactivity Substance abuse Obesity Social isolation Feelings of hopelessness, fear, and uncertainty are common effects of anxiety and osteoporosis. These feelings can cause a person to avoid following their treatment for either condition. When to See a Healthcare Provider When anxiety is excessive or ongoing, talking with your healthcare provider is best. This is especially true when it keeps you from your normal activities or causes work, school, physical health, and relationship problems. How to Seek Help In a Crisis If you or someone you know is having suicidal thoughts, contact the 988 Suicide & Crisis Lifeline at 988 for support and assistance from a trained counselor. If you or a loved one is in immediate danger, call 911. For more mental health resources, see our National Helpline Database. Diagnosis of Anxiety and Osteoporosis Mental health providers typically treat severe anxiety, but all healthcare providers may detect and manage anxiety. The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) helps providers diagnose mental disorders. Anxiety is diagnosed based on the duration and severity of symptoms, such as: Uneasiness or agitation Headaches, muscle aches, dry mouth, or nausea Panic attacks Problems sleeping Fatigue Difficulty concentrating Not enjoying things you previously enjoyed Avoiding work, school, or social events Inability to perform daily activities Problems managing emotions Frequent illness Decreased physical activity Healthcare providers use bone density tests to screen for and diagnose osteoporosis. This non-invasive, painless test uses a low dose of radiation to determine bone density and measure the amount of calcium and minerals in your bones. How Osteoporosis Is Diagnosed Self-Test for Anxiety Mental Health America (MHA) offers an online anxiety self-test based on the GAD-7 anxiety screening questionnaire from the American Psychiatric Association (APA). If your screening results indicate anxiety, reach out to a healthcare provider. A healthcare professional can make an accurate diagnosis. Treatment of Anxiety and Osteoporosis Anxiety treatment involves lifestyle modifications, medications, and psychotherapy (talk therapy). Osteoporosis treatment includes lifestyle changes, medications, and supplements. Medications Though this is not an exhaustive list, examples of common medications that treat anxiety include: Selective serotonin reuptake inhibitors (SSRIs): SSRIs increase serotonin levels which regulate mood, appetite, and the sleep-wake cycle. Examples include Prozac (fluoxetine), Celexa (citalopram), and Lexapro (escitalopram). Serotonin-norepinephrine reuptake inhibitors (SNRIs): SNRIs regulate serotonin and norepinephrine. Examples include Cymbalta (duloxetine) and Effexor (venlafaxine) Tricyclic antidepressants: These prevent the reabsorption of serotonin and epinephrine. Common examples include Elavil (amitriptyline) and Anafranil (clomipramine). Benzodiazepines: Benzodiazepines (benzos) slow down the central nervous system. They include Rivotril (clonazepam), Xanax (alprazolam), and Ativan (lorazepam). Benzos are typically a short-term solution reserved for severe anxiety. Notify Your Healthcare Provider Before Stopping Anti-Anxiety Medications Abruptly stopping anxiety medications could cause withdrawal symptoms. It’s essential to notify your healthcare provider before you stop taking them. Study: There’s No Perfect Way to Wean Yourself off of Antidepressants Osteoporosis treatment begins with lifestyle changes and supplements, such as calcium, vitamin D, magnesium, and omega-3 fatty acids. Post-menopausal women may receive hormone (estrogen) therapy to decrease osteoporosis risk. It may also involve the following medications: Biphosphonates: These increase bone density and include Fosamax (alendronate), Actonel (risedronate), and Boniva (ibandronate). Selective estrogen receptor modulators (SERMs): SERMs, such as Evista (raloxifene), mimic estrogen's effects to increase bone density (thickness). RANKL inhibitor: RANKL inhibitors, such as Prolia (denosumab), block a specific receptor in the body, which helps decrease bone breakdown. Many anxiety and osteoporosis medications can be taken together safely. This includes Prozac (fluoxetine) and Fosamax (alendronate), two of the most commonly prescribed medications for each. However, some anti-anxiety medications can increase the risk of falls and osteoporotic fractures. Osteoporosis medications, such as Fosamax (alendronate) and Actonel (risedronate), could increase the risk for depression and anxiety. This does not mean your healthcare provider won't prescribe these medications. But they may want to monitor you for unwanted side effects and interactions. What to Do When You Experience Unwanted Medication Side Effects If you experience adverse medication effects, notify your healthcare provider immediately. They may suggest adjusting your treatment. For example, if you experience anxiety with Fosamax (alendronate), they may switch you to Reclast (zoledronate) or Prolia (denosumab), which are less likely to cause anxiety. There are multiple options, and sometimes it takes a couple of tries to find the right combination. Psychotherapy Psychotherapy helps treat mental health disorders or disease-related stress. Types of therapy include: Cognitive behavioral therapy (CBT) Psychodynamic therapy Interpersonal therapy Exposure therapy Couples therapy (if relationship distress contributes to anxiety) Types of Therapy for Mental Health Coping With Anxiety and Osteoporosis Treating anxiety and osteoporosis requires professional help. However, there are lifestyle changes you can adpot during treatment to help with anxiety symptoms, bone health, and your overall health. Lifestyle Changes Healthy lifestyle changes that may increase your sense of well-being and bone health include: Exercise: Exercise releases serotonin and endorphins (mood-elevating chemicals). Weight-bearing activities like walking, hiking, or dancing can increase bone health. Eat a well-balanced diet: Incorporate fresh foods and healthy fats. Limit sugars, highly processed foods, tobacco, alcohol, and caffeine. Reduce stress: Stress reduction may include breathing exercises, massage, yoga, music, hobbies, aromatherapy, and mindfulness. Get enough sleep: If you have problems sleeping, it may help to evaluate your sleep hygiene. This might include beginning a nighttime routine, blocking out light, and creating a comfortable bedroom. A positive support system: Supportive relationships are beneficial for mental health and typically cause you to be more active. Fresh air: Incorporate more fresh air (less pollution) and green space into your days. Consider a pet: Interacting with an animal provides unconditional love and a sense of purpose. How Diet Affects Osteoporosis Risk If you have osteoporosis, preventing falls is also very important. Though this is not an exhaustive list, here are some fall prevention tips: Clear clutter on the floorAnchor loose cordsSecure throw rugsKeep kitchen drawers closedInstall grab bars in the bathroomTake care around liquid spills or slippery bathtubsUse assistive devices, such as canes or walkers, if you are unsteadyDon’t rush to move around (e.g., to answer the phone) Support Groups Support groups are beneficial because you can interact with those in similar situations. Ask your healthcare provider about local groups or explore one of the following online mental health support groups: Mental Health Strong Anxiety Anonymous DailyStrength Support Groups Support Groups Central How to Deal With Anxiety: Ways to Cope Online osteoporosis support groups include: Inspire American Bone Health Living With Osteoporosis Summary Anxiety is normal for short, brief periods. It becomes concerning when these symptoms linger or are out of proportion. Osteoporosis is a bone disease that thins your bones and increases the risk of fractures. Anxiety and osteoporosis share risk factors and have an impact on each other. Those with anxiety and depression are more susceptible to osteoporosis, and those with osteoporosis often experience anxiety. Treatment for each disease is multifaceted and includes a combination of lifestyle changes, medications, supplements, and psychotherapy. Exercise, proper nutrition, and getting more fresh air are lifestyle changes that can decrease anxiety and increase bone health. A Word From Verywell Anxiety disorders (ADs) and osteoporosis are not normal parts of aging. If you are coping with either, it’s best to seek treatment from a healthcare provider while incorporating lifestyle changes that are within your control. 21 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Centers for Disease Control and Prevention National Center for Health Statistics. Anxiety and depression: household pulse survey. U.S. Department of Health and Human Services. Osteoporosis workgroup. Ng JS, Chin KY. Potential mechanisms linking psychological stress to bone health. Int J Med Sci. 2021;18(3):604-614. doi:10.7150/ijms.50680 Kelly RR, McDonald LT, Jensen NR, et al. Impacts of psychological stress on osteoporosis: clinical implications and treatment interactions. Frontiers in Psychiatry. 2018;10(200). doi:10.3389/fpsyt.2019.00200 MedlinePlus. Stress. National Institute of Mental Health. Panic disorder: when fear overwhelms. Hong-Jhe C, Chin-Yuan K, Ming-Shium, T et al. The incidence and risk of osteoporosis in patients with anxiety disorder: a population-based retrospective cohort study. Medicine. 2016:95(38):e4912. doi:10.1097/MD.0000000000004912 Bandelow B, Michaelis S, Wedekind D. Treatment of anxiety disorders. Dialogues in Clinical Neuroscience. 2017:19(2):93-107. doi:10.31887/DCNS.2017.19.2/bbandelow American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-5-TR). National Institute of Mental Health. Anxiety disorders. Wilmer MT, Anderson K, Reynolds M. Correlates of quality of life in anxiety disorders: review of recent research. Curr Psychiatry Rep. 2021;23(77). doi:10.1007/s11920-021-01290-4 Substance Abuse and Mental Health Services Administration. Impact of the DSM-IV to DSM-5 changes on the national survey on drug use and health. Rockville (MD): Substance Abuse and Mental Health Services Administration (US); 2016: Table 3.15, DSM-IV to DSM-5 generalized anxiety disorder comparison. MedlinePlus. Bone density scan. American Psychiatric Association. GAD-7 patient questionnaire for anxiety. Mental Health America. Anxiety test. Sözen T, Özışık L, Başaran NÇ. An overview and management of osteoporosis. Eur J Rheumatol. 2017;4(1):46–56. doi:10.5152/eurjrheum.2016.048 Medline Plus. Raloxifene. Bolton JM, Morin SN, Majumdar SR, et al. Association of mental disorders and related medication use with risk for major osteoporotic fractures. JAMA Psychiatry. 2017;74(6):641–648. doi:10.1001/jamapsychiatry.2017.0449 Keshishi D, Makunts T, Abagyan R. Common osteoporosis drug associated with increased rates of depression and anxiety. Sci Rep. 2021;11(23956). doi:10.1038/s41598-021-03214-x Sarris J, O'Neil A, Coulson CE, et al. Lifestyle medicine for depression. BMC Psychiatry. 2014;14(107). doi:10.1186/1471-244X-14-107 Velten J, Bieda A, Scholten S et al. Lifestyle choices and mental health: a longitudinal survey with German and Chinese students. BMC Public Health. 2018: 18(632). doi:10.1186/s12889-018-5526-2 Additional Reading Hong-Jhe C, Chin-Yuan K, Ming-Shium, T et al. The incidence and risk of osteoporosis in patients with anxiety disorder: A Population-based retrospective cohort study. Medicine. 2016:95(38):e4912. doi: 10.1097/MD.0000000000004912 Kelly RR., McDonald LT, Jensen NR, Sidles S J, LaRue A C. Impacts of psychological stress on osteoporosis: Clinical implications and treatment interactions. Frontiers in Psychiatry. 2018;10(200). doi:10.3389/fpsyt.2019.00200 Ng JS, Chin KY. Potential mechanisms linking psychological stress to bone health. Int J Med Sci. 2021;18(3):604-614. doi:10.7150/ijms.50680 By Brandi Jones, MSN-ED RN-BC Brandi is a nurse and the owner of Brandi Jones LLC. She specializes in health and wellness writing including blogs, articles, and education. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit