Average Wholesale Price of HIV Drugs

Pills on twenty dollar bills
ccpixs.com/Chris Potter/Flickr/CC BY 2.0

The wholesale price of HIV drugs is determined by a number of factors. Firstly, an independent Wholesale Acquisition Cost (WAC) is released by the manufacturer, which is essentially the asking price of a drug before any discounts or rebates are added for volume purchases and/or prompt payment.

From this, a Suggested Wholesale Price (SWP) is set. This is the price recommended by the manufacturer to wholesalers when determining prices for their customers (i.e. retailers, hospitals, institutions). The SWP is not the actual transaction cost but rather a baseline from which wholesalers can make competitive pricing decisions.

By contrast, the Average Wholesale Price (AWP) is the average price that retailers and others are reportedly paying for a particular drug. The AWP is reported by the manufacturers and compiled by independent publishers, the data of which is used by governments, insurance companies, and others to determine the reimbursement and retail prices of prescription drugs. Because AWP relies on third-party reporting—and is, therefore, vulnerable to price manipulation—some institutions have begun to abandon its use in favor of the SWP.

Finally, the Direct Price (DIRP or DP) is the price a non-wholesale buyer (e.g. you) would expect to pay at the cash register. Generally speaking, there's a 20-30% markup between the WAC and DIRP.

Average Wholesale Price of Non-Generic Antiretroviral Drugs Per Month

Antiretroviral Drug Adult Strength Dose Count AWP
Aptivus (tiprianavir) 250mg capsule 2 twice daily 120 $1,685.59
Atripla (tenofovir + emtricitabine + efavirenz) 300/200/600mg tablet 1 daily 30 $2,869.86
Combivir (zidovudine + lamivudine) 300/150mg tablet 1 twice daily 60 $1,081.70
Complera (tenofovir + emtricitabine + ripilvirine) 300/200/25mg tablet 1 daily 30 $2,815.04
Crixivan (indinavir) 400mg capsule 2 twice daily 120 $365.42
Crixivan (indinavir) 400mg capsule 2 thrice daily 180 $548.12
Descovy (tenofovir AF + emtricitabine) 25/250mg tablet 1 daily 30 $1,759.73
Edurant (ripilvirine) 25mg tablet 1 daily 30 $1,075.15
Emtriva (emtricitabine) 200mg capsule 1 daily 30 $643.72
Epivir (lamivudine) 300mg tablet 1 daily 30 $498.89
Epzicom (abacavir + lamivudine) 600/300mg tablet 1 daily 30 $1,550.05
Evotaz (atazanavir + cobicistat) 350/150mg tablet 1 daily 30 $1,857.51
Fuzeon (enfuvirtide) 90mg injection 1 twice daily 60 $4,097.78
Genvoya (elvitegravir + cobicistat + emtricitabine + tenofovir alafenamide) 150/150/200/10mg tablet 1 daily 30 $3,093.19
Intelence (etravirine) 200mg tablet 1 twice daily 60 $1,306.08
Isentress (raltegravir 400mg tablet 1 twice daily 60 $1,545.07
Invirase (saquinavir) 500mg tablet 2 twice daily 120 $1,260.01
Kaletra (lopinavir + ritonavir) 200/50mg tablet 2 twice daily or 4 daily 120 $1,106.29
Lexiva (fosamprenavir) 700mg tablet 2 twice daily 120 $2,408.86
Lexiva (fosamprenavir) 700mg tablet 1 twice daily or 2 once daily 60 $1,204.43
Norvir (ritonavir) 100mg tablet 1 daily 30 $308.60
Odefsey (rilpivirine + tenofovir AF + emtricitabine) 25/25/200mg tablet 1 daily 30 $2,815.04
Prezista (darunavir) 400mg tablet 2 daily 60 $1,626.06
Prezista (darunavir) 600mg tablet 1 twice daily 60 $1,629.06
Prezcobix (darunavir + cobicistat) 80/150mg tablet 1 daily 60 $1,862.12
Rescriptor (delavirdine) 200mg tablet 2 thrice daily 180 $365.45
Retrovir (zidovudine) 300mg tablet 1 twice daily 60 $390.97
Reyataz (atazanavir) 200mg capsule 2 daily 60 $1,656.52
Reyataz (atazanavir) 300mg capsule 1 daily 30 $1,646.80
Selzentry (maraviroc) 150mg tablet 1 twice daily 60 $1,296.77
Selzentry (maraviroc) 300mg tablet 1 twice daily 60 $1,296.77
Stribild (tenofovir + emtricitabine + elvitegravir + cobicistat) 300/200/150/ 150mg tablet 1 daily 30 $3,244.76
Sustiva (efavirenz) 600mg tablet 1 daily 30 $1,010.13
Tivicay (dolutegravir) 50mg tablet 1 daily 30 $1,707.26
Tivicay (dolutegravir) 50mg tablet 1 twice daily 60 $3,414.52
Triumeq (abacavir + lamivudine + dolutegravir) 600/300/50mg tablet 1 daily 30 $2,889.22
Trizivir (abacavir + zidovudine + lamivudine) 300/300/100mg tablet 1 twice daily 60 $1,931.64
Truvada (tenofovir + emtricitabine) 300/150mg tablet 1 daily 30 $1,759.73
Tybost (cobicistat) 150mg tablet 1 daily 30 $230.90
Videx EC (didanosine) 400mg capsule 1 daily 30 $515.84
Viracept (nelfinavir) 625mg tablet 2 twice daily 120 $1,169.22
Viramune (nevirapine) 200mg tablet 1 twice daily 60 $912.86
Viramune XR (nevirapine) 400mg tablet 1 daily 30 $846.66
Viread (tenofovir) 300mg tablet 1 daily 30 $1,197.32
Vitekta (elvitegravir) 85mg tablet 1 daily 30 $1,445.34
Vitekta (elvitegravir) 150mg tablet 1 daily 30 $1,445.34
Zerit (stavudine) 40mg capsule 1 twice daily 60 $553.12
Ziagen (abacavir) 300mg tablet 2 daily 60 $670.37
Was this page helpful?

Article Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial policy to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.