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Our Top Picks

Best Overall: TUMS Ultra Strength 1000 at Amazon

"A trusted brand that’s been in the heartburn business for years."

Best Heartburn Relief: Alka-Seltzer ReliefChews at Amazon

"A tasty twist on the original that provides relief just the same."

Best Liquid Antacid: Mylanta Maximum Strength at Amazon

"It works much more quickly than tablets and tastes good, too."

Best Chewable Antacid: SoundHealth Extra Strength at Amazon

"They work just as well as the pricier, more well-known brands."

Best Flavored Antacid: TUMS Antacid Chewy Bites at Amazon

"Customers also love the assorted berry flavors."

Our Top Picks

Best Overall: TUMS Ultra Strength 1000 Assorted Tropical Fruit Antacid

Dealing with GERD is rough. When you think heartburn, you likely think Tum. Tum. Tum. Tum. TUMS. That’s not only due to their catchy commercials, but because they’re a trusted brand that’s been in the heartburn business for years.

The primary ingredient in TUMS is calcium carbonate, which acts quickly on symptoms of indigestion, heartburn, and sour stomach. In addition, two tablets provide 80 percent of your calcium for the day. (The recommended serving is two or three tablets when symptoms strike, but no more than seven in one day.) Customers say TUMS taste great, work quickly to ease indigestion and heartburn, and, overall, are hard to beat. However, if you have severe and persistent symptoms, make sure to see your doctor.

Best Heartburn Relief: Alka-Seltzer Relief Chews Heartburn Assorted Fruit

When you move past the mild discomfort of indigestion and feel the more intense discomfort of heartburn, you need something that works fast to quell that burning. These chews from Alka-Seltzer promise to do just that. They’re a tasty twist on the original that provides relief just the same.

Customers say the fruit-flavored chews are a great alternative to other chalky tablets, and have a pleasant taste. More importantly, they say these chews provide fast and effective relief from heartburn.

Best Liquid Antacid: Mylanta Maximum Strength Antacid, Classic Flavor, 12 Ounce

When you want relief from indigestion and heartburn stat, a swig of Mylanta promises to deliver just that. This maximum-strength formula works on contact and it also provides relief from gas and the painful bloating that typically accompanies it.

Mylanta comes in classic mint, caramel and vanilla flavors, and it can be taken anytime, day or night. While it’s designed to provide powerful relief, the formula is also gentle enough that it can be taken every day.

Customers say it works much more quickly than tablets and tastes good, too. Many say it’s the only over-the-counter antacid that works for them.

Best Chewable Antacid: SoundHealth Extra Strength Antacid Chews

For a straightforward chewable antacid at an affordable price, there are fruit-flavored chews from SoundHealth. Designed to treat indigestion, sour stomach and heartburn, they’re recommended for adults and children 12 years-of-age and older. If you have a kid with persistent GERD, make sure to see a pediatrician.

Customers say they work just as well as the pricier, more well-known brands, and they love the taste. They say they’re not chalky and taste a bit like Skittles.

Best Flavored Antacid: TUMS Antacid Chewy Bites, Assorted Berries

If you’re not a fan of the chalky taste that comes with some antacids, these chewy bites from TUMS are a welcome twist. Customers also love the assorted berry flavors, And more importantly, they say they get the job done. The job, of course, being to provide relief from occasional indigestion and heartburn.

They trust the TUMS brand, and say for occasional heartburn these chewables are hard to beat. The only downside reported is that they taste so good, you may find yourself wanting to eat more than you should.