Best At-Home STI Tests

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Sexually transmitted infections, otherwise known as STDs or STIs, are incredibly common. If you are sexually active, you are potentially at risk. How common are they? Well, that depends on the STI.

Here are a few of the most common conditions tracked by the Centers for Disease Control and Prevention (CDC):

  • More than 1 out of every 6 people aged 14 to 49 years have genital herpes.
  • Between two and three million new chlamydia infections happen every year. Around 1 in every 20 young women between the ages of 14 and 24 have chlamydia.
  • After dropping for many years, the rate of syphilis is again on the rise.

These numbers may seem high or even unrealistic. That’s because most people living with STIs don’t know they have them. The vast majority of STIs go unrecognized, sometimes for years or even decades. The lack of detection is largely due to people with STIs having no noticeable symptoms. 

The only way to know whether or not you have an STI is to get tested. Unfortunately, testing isn’t a standard part of medical care in the United States. Doctors regularly check their patients’ blood pressure. They don’t regularly check if they have an STI. 

The 8 Best At-Home STI Tests of 2022

Best Overall : Everlywell


Everlywell

Everlywell

Key Specs
  • Type of Testing: Self-collected samples
  • STI Tests Available: Chlamydia, gonorrhea, syphilis, trichomoniasis, Hepatitis C, HIV, herpes
  • Time to Receive Results: The website says "within days"
  • Cost: $49 to $149, coupons available
Why We Chose It

The Everlywell test kit uses different methodologies for testing men and women. Men are tested with urine and blood, and women with vaginal swabs and blood. The site offers consults for positive results through their independent physician network, and there may be options for treatment. You can pay for your tests using an FSA/HSA card.

Best for Quick Results : STDCheck.com


STDCheck.com

STDCheck.com

Key Specs
  • Type of Testing: Lab-based testing
  • STI Tests Available: Chlamydia, gonorrhea, syphilis, HIV, early HIV, Hepatitis A, B & C
  • Time to Receive Results: 1 to 2 days
  • Cost: $24 to $259
Why We Chose It

With STDCheck.com, you choose which STI tests you’re interested in and order them online or by phone. That order is then sent to a lab near you, where you provide a urine and/or blood sample. This company has an option for HIV tests that can detect a new infection. It also provides in-depth information about each STI tested for. You can use an FSA or HSA card to pay for these tests. A doctor is also available for you to consult with by phone. 

Best for Quick Treatment : LetsGetChecked


Let’s Get Checked

Let’s Get Checked

Get 25% off with code VERYWELL25

Key Specs
  • Type of Testing: Self-collected sample
  • STD Tests Available: Chlamydia, gonorrhea, trichomoniasis, syphilis, HIV, herpes, ureaplasma, gardnerella, mycoplasma
  • Time to Receive Results: 2 to 5 days
  • Cost: $99 to $249
Why We Chose It

To use these tests you will be asked to collect urine in a sample tube and/or prick your finger for blood. LetsGetChecked laboratories are CLIA-certified and CAP and ISO-accredited and use capillary testing; it's a simple and painless blood testing method that is as accurate as a venous blood draw. 

Some collection kits for this company can also be purchased at CVS. A nurse will call you if you test positive to help you figure out what to do next. If you test positive, you can start a virtual consultation with a LetsGetChecked healthcare provider for $39. They are also available to answer questions throughout the testing process.

When there is a positive result for chlamydia, trichomoniasis, bacterial vaginosis (caused by Gardnerella), mycoplasma, or ureaplasma, LetsGetChecked can send your agreed-upon treatment directly to your home at no additional cost. Please note that any medication prescribed will be an added cost. Your data is never shared with a third party, and it is completely anonymized.

Doctor consultations are not available.

Best for Test Options : Persona Labs


Persona Labs

Persona Labs

Use code Very10 for 10% off your purchase.

Key Specs
  • Type of Testing: Lab-based testing
  • STD Tests Available: Chlamydia, gonorrhea, syphilis, HIV, HIV-related, Hepatitis A, B & C, herpesvirus, Human Immunodeficiency Virus
  • Time to Receive Results: 2 to 10 business days
  • Cost: $46 to $281
Why We Chose It

Persona Labs offers more STI testing options than many other companies, but it is difficult to navigate. There is also relatively little information about STIs for which testing is offered. However, doctors consultations are available, and they will prescribe prescriptions to treat certain STIs. 

Best for Payment Options : HealthLabs.com


HealthLabs.com

HealthLabs.com

Key Specs
  • Type of Testing: Lab-based testing
  • STI Tests Available: Chlamydia, gonorrhea, trichomoniasis, syphilis, HIV, early HIV, Hepatitis B & C, herpes type 1 and 2
  • Time to Receive Results: 1 to 3 business days
  • Cost: $99 to $349
Why We Chose It

Like most lab-based testing companies, with HealthLabs.com you choose which STI tests you’re interested in and order them online or by phone. That order is then sent to a lab near you, where you provide a urine and/or blood sample. This company has an option for HIV tests that can detect a new infection, and they also provide good information about appropriate testing windows for all of their options. You can use an FSA or HSA card to pay for these tests. The company provides have specialists who will help you understand your results, and physicians are available for a consultation if your results mandate it. 

Best Direct : QuestDirect


QuestDirect

QuestDirect

Key Specs
  • Type of Testing: Lab-based testing
  • STI Tests Available: Chlamydia, gonorrhea, trichomoniasis, syphilis, herpes simplex 1 and 2, HIV, early HIV, Hepatitis B & C
  • Time to Receive Results: Typically within 3 to 5 business days
  • Cost: $49 to $379
Why We Chose It

Many other at-home STI tests will send you to Quest for testing. Using QuestDirect cuts out the middle man. Quest also offers confirmatory testing for several STIs, which reduces the risk of a false positive. However, the STI testing information on their site is less comprehensive than many. In addition, this company does not connect you to a healthcare provider. 

Best for Self-Collecting : NURX


NURX

NURX

Key Specs
  • Type of Testing: Self-collected samples
  • STI Tests Available: Chlamydia, gonorrhea, trichomoniasis, syphilis, HIV, Hepatitis C 
  • Time to Receive Results: Within 7 business days
  • Cost: $150 to $220, accepts insurance
Why We Chose It

Although self-collected samples aren’t necessarily as good as samples taken in the lab, NURX tests do one very smart thing. Instead of just collecting urine and/or blood, they also have you collect a vaginal swab, throat swab, and/or rectal swab. This makes it possible to test for oral and anal STIs that might otherwise be missed. Because of this, NURX tests might be a better option than some lab-based tests for individuals who have condomless sex. In addition, they provide unlimited access to a medical team.

Best for Couples : MyLAB Box


MyLabBox

MyLabBox

Key Specs
  • Type of Testing: Self-collected samples
  • STI Tests Available: Chlamydia, gonorrhea, syphilis, trichomoniasis, HPV, herpes, HIV, mycoplasma. PreP and vaginal discharge options are available. 
  • Time to Receive Results: 2 to 5 days
  • Cost: $79 to $369, $499 for a couple’s kit, coupons available 
Why We Chose It

My Lab Box offers kits that allow you to self swab the mouth and rectum, not just test for genital STIs. They also have several additional test options, such as a kit that provides tests for both parts of a couple, and tests to diagnose different causes of vaginal discharge. It has some information about each STI, but no good information about testing windows. Physician consults are available if you test positive, and it may be possible to get a prescription for treatment. Otherwise, a certified STI counselor is available, but not a physician. 

FAQs

Why should you consider an at-home STI test?

Because STI testing isn’t usually a part of preventative health care, people generally have to ask for an STI test if they want one. This can feel embarrassing depending on who you are. Worse, doctors are not always aware of STI test options or know how to order them for you. They may also feel embarrassed talking about sex and sexual risk, just like their patients. In addition, some people are worried about their doctor or health insurer knowing anything about their sexual history. That can make them reluctant to seek out testing through the usual channels, even if testing in a doctor’s office may well be covered by insurance.

For these and other reasons, there has been a growing interest in at-home STI testing. However, not all at-home STI tests are the same. The most accurate at-home STI tests are the same tests that you’d get in a doctor’s office. The only difference is that instead of getting a doctor to order them for you, you order them online. Then you go to a commercial laboratory and they take a urine sample and/or blood. There are also at-home testing kits that allow you to collect your own sample of urine or saliva and send it to a company for testing. These tests are likely to be less accurate than lab-based testing. Below, we've highlighted both options, so you can read on to see which route you feel most comfortable with.

What makes for a good at-home STI test?

  • It provides clear information about what STIs are being tested for
  • You are able to get tested for any STI you might be worried about
  • Results are provided in a clear manner, with access to a healthcare professional for more information
  • The testing company will link you to treatment and/or further testing as appropriate

What STIs Should I Get Tested For? 

The U.S. Preventative Services Task Force (USPSTF) is an independent agency that makes recommendations for improving the public’s health. The CDC is a government agency that also makes recommendations for treatment. Each agency’s recommendations for who should get screened are summarized below.

Other FAQs

Why You Should Trust Our Recommendations

If you know or suspect you have been exposed to an STI, these guidelines do not apply. They are designed to recommend whether the general population should be tested. If you know or suspect you have been exposed to an STI, testing is a good idea.

The author of this guide, Elizabeth Boskey, has been a sexual health educator for more than 20 years. She has a Masters in Public Health and a Ph.D. focused on women’s reproductive health. In her professional capacity, she has counseled individuals about STI testing and fertility and taught about sexual health at the undergraduate and graduate levels. Review criteria are objective, and screening recommendations are based on evidence.  

woman sitting in patient room with gynecologist
stefanamar / Getty Images
Article Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. Center for Disease Control and Prevention. Sexually transmitted diseases.

  2. Centers for Disease Control and Prevention. Genital herpes – CDC fact sheet.

  3. Centers for Disease Control and Prevention. Chlamydia – CDC fact sheet (detailed).

  4. Centers for Disease Control and Prevention. Sexually transmitted disease surveillance 2018: syphilis.

  5. Aral SO, Over M, Manhart L, Holmes KK. Sexually transmitted infections. Disease Control Priorities in Developing Countries. 2nd ed. World Bank; 2006.

By Elizabeth Boskey, PhD
Elizabeth Boskey, PhD, MPH, CHES, is a social worker, adjunct lecturer, and expert writer in the field of sexually transmitted diseases.