The 7 Best Hair Loss Treatments for Men of 2021

Keep a full head of hair with these OTC products

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First Look

Best Overall: Men’s Rogaine 5% Minoxidil Foam at Amazon

"This is perfect for early stages of hair loss and is supposed to regrow up to 25 percent more hair."

Best Budget: Equate Men’s Hair Regrowth Treatment at Amazon

"This extra strength solution is designed to revitalize hair follicles just as well as any lavish formula."

Best Conditioner: Amplixin Energizing Conditioner at amplixin.com

"Works to get deep into the scalp to moisturize hair follicles and improve thickness."

Best Shampoo: Nioxin Cleanser Shampoo at Amazon

"This is a trusted option for men with non-chemically treated hair and light thinning."

Best Natural: Botanical Green Care Hair Loss Treatment at Amazon

"Not only will this treatment help you walk away with thicker hair, but it’ll leave you smelling like a freshly planted garden."

Best Laser: HairMax Prima 9 LaserComb at Bed Bath & Beyond

"This has nine medical-grade lasers that work together to directly target hair follicles on a cellular level."

Best Serum: Propidren by Hairgenics Hair Growth Serum at Amazon

"This stops hair loss and helps thicken follicles through the regrowth process by leaning on saw palmetto to help block DHT."

Dealing with premature hair loss is difficult enough on its own, so it's important to find a treatment process that is simple and effective from the get-go. 

“When things go wrong with the hair, they can have profound effects on people's well-being, their self-esteem, and their mental state,” explains Ramsay Farah, MD, chief of dermatology at SUNY Upstate and dermatologist at Farah Dermatology and Cosmetics.

No matter how isolated you may feel in your hair loss journey, it's a common condition. In fact, Farah says nearly all men will suffer from hair loss to some degree. The most common type of hair loss in men is referred to as androgenetic alopecia, “which is basically a combination of genetics and a profile of hormones that come together, and cause men to lose their hair in a fairly predictable fashion,” according to Farah. 

As a dermatologist, he highly recommends seeking out specialized help from a doctor because dermatologists are trained in hair, skin, and nails and the treatment process will likely end in a better result. Generally, when patients come to see Farah with hair loss issues, his first step is to look at the patient’s history: what medications they’re on, what their family history is, and what their medical history is. Then he conducts a physical exam where he analyzes the scalp, skin, and hair to check for any potential signs of medical conditions and carefully examine hair follicles. In some cases, he even gets the patient's blood drawn to check for thyroid disease, connective tissue diseases, or other immune disease such as lupus. These elements all help inform proper treatment options. 

Although Farah does warn against some OTC remedies that don’t have the proper scientific rigor behind them, these drug store options are a great place to start. 

Our Top Picks

Best Overall: Men’s Rogaine 5% Minoxidil Foam

Even if you haven't tried it yet, you've probably heard of Rogaine. Rogaine's formula fosters hair growth that can be seen in as little as 12 weeks after daily use. Rogaine stimulates hair growth through its active ingredient, minoxidil, which boosts follicle activity and protein production. Farah says minoxidil is a common option for hair loss treatment that doesn’t require a prescription. This foam formula is perfect for the early stages of hair loss and is supposed to regrow up to 25 percent more hair. With its botanical extracts and moisturizing features, Rogaine not only encourages hair growth but also nourishes the scalp. 

Best Budget: Equate Men’s Hair Regrowth Treatment

This formula from Equate, with its 5 percent concentration of minoxidil, is ideal for men dealing with general thinning on the top of their scalp—not those experiencing frontal balding or a receding hairline. This extra strength solution is designed to revitalize hair follicles just as well as any lavish formula. With just one mL drop near the desired area twice a day, Equate works to reverse any general hair loss. 

Best Conditioner: Amplixin Energizing Conditioner

Amplixin

Using a trusted conditioner is the second step in the hair-loss treatment process. Amplixin Energizing Conditioner works to get deep into the scalp to moisturize hair follicles and improve thickness. The formula is composed of natural argan oil and Ampligro Complex, which contains revitalizing caffeine and a blend of bio-mimetic peptides. This Amplixin product promises to slow down hair loss and fight against DHT when used properly. Lather this conditioner into the roots of wet hair for three to five minutes and rinse out thoroughly for a minimum of three times per week. 

Best Shampoo: Nioxin Cleanser Shampoo

One of the easiest products to use while looking to bounce back from early hair loss is a specialized shampoo. Nioxin’s System 1 Cleanser Shampoo is a trusted option for men with non-chemically treated hair and light thinning. The formula’s blend of botanical and humectants are said to work hard to remove buildup and toxins without stripping away essential oils from follicle sites, allowing hair to grow healthily with plenty of volume and shine. 

For the best results, gently massage the shampoo into your wet hair and scalp for one minute and then rinse thoroughly. This shampoo is meant for daily use to help you create a healthier scalp. 

Best Natural: Botanical Green Care Hair Loss Treatment

Composed of 100 percent organic and natural ingredients, this formula from Botanical Green Care contains active ingredients set to reduce hair loss, stimulate hair growth, and encourage dormant hair follicles to function again. Its unique blend of ingredients also includes saw palmetto to help regrow hair and cayenne extract to increase blood circulation throughout the scalp to encourage new growth. 

Not only will this treatment help you walk away with thicker hair, but it’ll leave you smelling like a freshly planted garden. Massage the liquid formula into your hair and scalp and results will start to show in as little as three months.

Best Laser: HairMax Prima 9 LaserComb

HairMax Prima 9 LaserComb
Courtesy of Bed Bath & Beyond.

Laser treatment can be expensive and it’s hard to know how your body will react to low-level light therapy. But if you haven’t had any luck with more traditional regrowth treatments, this laser may be the next option for you. The HairMax Prima 9 LaserComb has nine medical-grade lasers that work together to directly target hair follicles on a cellular level. Reportedly, with as little as 11 minutes of use every other day, on average this FDA-cleared comb can help grow 129 additional new hairs per sq. inch after 12 to 16 weeks.

Best Serum: Propidren by Hairgenics Hair Growth Serum

With a 30-day full money-back guarantee, you really have nothing to lose by trying Propidren by Hairgenics Hair Growth Serum. This serum stops hair loss and helps thicken follicles through the regrowth process by leaning on saw palmetto to help block DHT. It also contains biotin, which strengthens weak and brittle hair. After at least three months of dropping one mL on a dry head of hair near the desired area twice a day, you should start to see a stop in hair loss and an increase in significant hair growth.

Final Verdict

For a reliable hair loss treatment that’s available OTC and has minimal side effects, look no further than Rogaine. Your best bet is to use Men’s Rogaine 5% Minoxidil Foam as your first introduction into the hair loss treatment arena and then move onto a shampoo like Nioxin Cleanser Shampoo for more in-depth cleansing. Although “miracle products” can be found nearly everywhere, they may not give you the instant results you're looking for, and you should discuss them with your doctor before use.

What to Look for in Hair Loss Treatments for Men

Method of Application

Rogaine is sold as both a foam and a liquid, but other OTC treatments come in a variety of forms: shampoos, serums, conditioners, and even oral supplements. The type of application you choose mostly depends on your convenience; if you struggle to apply a liquid form, foam might be easier. You might feel like hair loss shampoo doesn’t really “clean” your hair, and prefer to follow-up a regular washing with a specialized conditioner instead. Before trying a new product, talk to your dermatologist to ensure that you're not at risk for any potential drug interactions or skin irritations.

DHT Blocker

According to the Society for Endocrinology, dihydrotestosterone, or DHT, is one of the primary hormones responsible for the development of male characteristics (it’s often credited with kick-starting puberty and contributing to the growth of body hair and prostate growth). But it can also frequently be blamed for hair loss in older men, especially if your body produces too much of it.

Treatments with ingredients that block DHT can go a long way toward preventing hair loss. One of the most common DHT-blocking ingredients is saw palmetto, a botanical supplement that can be used to treat urinary and prostate problems as well as hair loss.

“Saw palmetto affords some benefit as it lowers the testosterone levels that are driving the hair loss,” advises Caren Campbell MD, a San Francisco-based dermatologist. So far, the studies on using saw palmetto for hair loss have been small but positive. 

Peptides

If you decide to go the shampoo route to treat your thinning hair, try to choose one with peptides: “Peptides are messengers that tell the skin to do a specific function,” says Joshua Zeichner, MD, associate professor of dermatology at Mount Sinai Hospital. “[While] some peptides stimulate collagen, others reduce inflammation, and there is a group that may enhance the activity of hair follicles [often found in shampoos designed to enhance hair growth].”

There are dozens of shampoos made with peptides to boost hair growth. You may also want to look for one that contains keratin, collagen, or biotin to maximize hair health, strength, and growth.

Proven Results

Dr. Campbell stresses that, for most men experiencing hair loss, minoxidil (or Rogaine) is not only the most reliable treatment but is the safest one, too.

“Rogaine is the best OTC treatment for hair loss in men who are suffering from androgenetic alopecia, a.k.a. male pattern baldness,” she says. “There are a slew of products, [many fake], that won't do anything and can even do more harm than good.”

In other words, don’t waste time (or, worse, put yourself at risk of harmful side effects) by messing around with off-brand treatments promising to work miracles. Stick to products that have shown results, like minoxidil, which Dr. Zeichner calls the gold standard for the treatment of hair thinning.

“Hair growth is slow—typically about a half an inch per month,” says Dr. Zeichner. “If you see any photos that look too good to be true, they probably are.”

“Medications, illness, and stress can cause hair loss, [as well as] iron deficiency, thyroid issues, autoimmune conditions, and a number of other things. Not all are treated the same. It’s best to get the type of hair loss you are suffering from diagnosed, and then treatment can be tailored to you.”Caren Campbell, MD, San Francisco-based dermatologist

Why Trust Verywell Health?

Having been raised by two medical professionals, Amari Pollard understands the importance of health literacy. As a seasoned health writer, she is committed to producing well-researched and well-sourced product reviews to help people make informed medical decisions.

Additional reporting for this story by Sarah Bradley

Sarah Bradley has been writing health content since 2017—everything from product roundups and illness FAQs to nutrition explainers and the dish on diet trends. She knows how important it is to receive trustworthy and expert-approved advice about over-the-counter products that manage everyday health conditions, from GI issues and allergies to chronic headaches and joint pain.

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  1. Society of Endocrinology. Dihydrotestosterone. Updated February 2018.

  2. National Center for Complementary and Integrative Health. Saw palmetto. Updated May 2020.