Cold & Flu Print The 8 Best Medicines for a Stuffy Nose of 2019 Put down the tissue box and start breathing easy By Abby Stassen Updated July 02, 2019 Medically reviewed by Richard N. Fogoros, MD More in Cold & Flu Prevention Symptoms Treatment Common Cold Flu Related Illnesses Our editors independently research, test, and recommend the best products; you can learn more about our review process here. We may receive commissions on purchases made from our chosen links. First Look Mucinex Sinus Max Severe Congestion & Pain at Amazon"Triple threat of stuffy nose treatments may reduce your congestion and uncomfortable symptoms that come along with it."Equate Congestion Suphedrine PE Nasal Decongestant at Walmart"Non-drowsy formula is ideal for daytime use."Advil Sinus Congestion & Pain Relief at Amazon"Sinus headaches don’t stand a chance."Robitussin Severe CF Maximum Strength Cold, Cough & Flu at Amazon"Active ingredients include acetaminophen for pain, phenylephrine for your stuffy nose, and guaifenesin and dextromethorphan to treat your cough."Mucinex Sinus Max Nasal Spray at Amazon"Concentrated vapor burst delivers its active ingredients right to your inflamed nasal tissues."NoseFrida The SnotSucker Baby Nasal Saline Kit at Amazon"A doctor-invented aspirator that clears your baby’s nasal passages, helping them breathe better while they sleep, play, and eat."Vicks DayQuil Cold & Flu Multi-Symptom Relief at Amazon"These liquid capsules relieve six different symptoms of cold and flu."Vicks NyQuil Severe Cough Cold & Flu Nighttime Relief at Amazon"An old standby that helps you get the rest your immune system needs to fight off your stuffy nose." Our Top Picks Mucinex Sinus Max Severe Congestion & Pain Buy on AmazonBuy on TargetBuy on Walmart To defeat severe congestion that’s interfering with your day, you need a powerful medication that won’t let you down. Mucinex’s Sinus Max is an over-the-counter tablet that attacks congestion and several other symptoms associated with stuffy noses. These tablets contain phenylephrine, an ingredient used to relieve nasal discomfort associated with congestion and other conditions. It also has acetaminophen, an effective pain reliever, as well as guaifenesin, which is used to help clear mucus that may drip down the back of your throat and get caught in your lungs. This triple threat of stuffy nose treatments may reduce your congestion and uncomfortable symptoms that come along with it. If you’re experiencing these symptoms along with significant fatigue and sneezing, you might have a cold. Check out our best cold medicines for more treatments. Equate Congestion Suphedrine PE Nasal Decongestant Courtesy of Walmart Buy on Walmart If you’re dealing with a stuffy nose that’s affecting your productivity, but you don’t want to spend a lot to clear it up, Equate’s Congestion medication offers the same effectiveness as name brand medications in a budget-friendly tablet. Equate’s medication contains 10 mg of phenylephrine, the same effective active ingredient that’s found in name-brand decongestants. The non-drowsy formula is ideal for daytime use. Advil Sinus Congestion & Pain Relief Buy on AmazonBuy on Walmart Stuffy noses and sinus headaches often go hand in hand. When the tissues in your nose swell up from congestion, it can put pressure on your sinus cavities. Nasal discharge can also irritate your sinuses, setting the stage for a distracting, painful sinus headache. Luckily, there are over-the-counter options that can relieve the pressure and pain from sinus headaches, and Advil’s Sinus Congestion & Pain Relief is up to the task. Sinus headaches don’t stand a chance against this over-the-counter medication. It contains ibuprofen, an NSAID used to treat mild to moderate pain and swelling. Phenylephrine also makes an appearance in this stuffy nose treatment, reducing congestion that causes pressure in your sinus cavities. Robitussin Severe CF Maximum Strength Cold, Cough & Flu Buy on Amazon It’s not uncommon to experience a cough alongside your stuffy nose. Post-nasal drip occurs when the fluid from your stuffy nose runs down the back of your throat. If it drains into your lungs, your body will start coughing to try and get it out. Robitussin’s Severe CF Maximum Strength Liquid helps relieve congestion and quiet your cough. This medication’s active ingredients include acetaminophen for pain, phenylephrine for your stuffy nose, and guaifenesin and dextromethorphan to treat your cough. Guaifenesin thins and loosens the mucus in your airways to help you breathe easier without coughing, and dextromethorphan suppresses your cough so you can get on with your day. Mucinex Sinus Max Nasal Spray Courtesy of Amazon Buy on Amazon If you’re struggling with a stuffy nose but don’t want to take a pill to treat it, Mucinex’s Sinus Max Clear and Cool Nasal Spray offers instant relief with a refreshing menthol twist. This powerful spray contains oxymetazoline, a common decongestant in nasal sprays that’s been proven to reduce swelling and stuffiness in your nose. The spray’s concentrated vapor burst delivers its active ingredients right to your inflamed nasal tissues—you’ll notice a refreshing blast of menthol right after you use it. It offers relief from your stuffy nose for up to 12 hours, so you won’t have to re-spray throughout the day. When stuffy noses occur alongside a fever and extreme tiredness, it can signal the start of the flu. Here are our suggestions for the best OTC flu meds. NoseFrida The SnotSucker Baby Nasal Saline Kit Buy on AmazonBuy on Walmart Stuffy noses are frustrating for adults, but babies have it even tougher. They’re unable to blow their noses, so they’re stuck with congestion that may affect their breathing and make feedings more difficult. Luckily, you can help your little one out with NoseFrida’s SnotSucker Baby Nasal Saline Kit. This kit raises some eyebrows with a name like “SnotSucker,” but the user-friendly device is well worth it. It’s a doctor-invented aspirator that clears your baby’s nasal passages, helping them breathe better while they sleep, play, and eat. First, you’ll soften your baby’s mucus with a gentle saline mist, then place the tube against your baby’s nasal passage to form a seal. You can gently use your mouth to suck the congestion out from the other side of the tube—but don’t worry, there’s a hygiene filter to keep your baby’s boogers away from your mouth. Vicks DayQuil Cold & Flu Multi-Symptom Relief Buy on AmazonBuy on Cvs.com Having a sore throat on top of a stuffy nose can make it harder to get through your day. Vicks DayQuil Cold & Flu Multi-Symptom Relief is a non-drowsy medication that tackles both. These liquid capsules relieve six different symptoms of colds and flus, but they’re especially effective on stuffy noses and sore throats. Acetaminophen takes care of the pain associated with your sore throat, while phenylephrine dries up mucus in your nose and reduces swelling. The liquid capsule format releases the medication more quickly than a tablet, and spares the mess of a liquid formula. If you need a little more help for a bad sore throat, you can take a look at our picks for the best medicines for a sore throat. Vicks NyQuil Severe Cough Cold & Flu Nighttime Relief Buy on Amazon A stuffy nose doesn’t just slow you down during the day—it can also affect the quality of your sleep. You can’t breathe through your nose as well when it’s stuffed up, and that can cause nighttime awakenings. NyQuil is an old standby that helps you get the rest your immune system needs to fight off your stuffy nose. Nyquil’s Severe formula contains an antihistamine to relieve itchiness and congestion. It also promotes drowsiness, reducing the number of times you have to wake up and blow your nose during the night. This formula has a cough suppressant and a mild pain reliever, so you can catch up on your sleep despite your stuffy nose. Our writers spent 4 hours researching the most popular medicines on the market. Before making their final recommendations, they considered 17 different medicines overall, screened options from 13 different brands and manufacturers, read over 24 user reviews (both positive and negative), and tested 5 of the medicines themselves. All of this research adds up to recommendations you can trust. Was this page helpful? Thanks for your feedback! Looking to avoid getting the flu? Our free guide has everything you need to stay healthy this season. Sign up and get yours today. Email Address Sign Up There was an error. Please try again. Thank you, , for signing up. What are your concerns? Other Inaccurate Hard to Understand Submit Article Sources Phenylephrine. MedlinePlus Drug Information. MedlinePlus. Dextromethorphan. MedlinePlus Drug Information. MedlinePlus. Acetaminophen Information. U.S. Food and Drug Administration. Treatments for post-nasal drip. Harvard Health Publishing. Harvard Medical School. Guaifenesin (Oral Route). Drugs and Supplements. Mayo Clinic.