The 7 Best Over-the-Counter Yeast Infection Medicines of 2019

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First Look

Monistat 1-Day Maximum Strength at Amazon

"Requires just one day of treatment."

Vagistat 3 at Amazon

"For a simple, three-day yeast infection treatment."

NutraBlast Boric Acid Suppositories at Amazon

"Supports pH balance and overall vaginal health."

Yeastgard Advanced Homeopathic Caps at Amazon

"If you’d rather take a pill than use creams and inserts."

Taro Clotrimazole 7 Vaginal Cream at Amazon

"Doesn't burn and works as well as higher-priced products."

Vagisil Instant Anti-Itch Crème at Amazon

"Immediate relief from the itching and burning."

Monistat 7-Day at Target

"Doctors say that longer treatments are better during pregnancy."

Our Top Picks


Monistat 1-Day Maximum Strength Vaginal Antifungal

When it comes to the treatment of a yeast infection and relief from its accompanying symptoms, many women trust Monistat. This maximum strength formula requires just one day of treatment and promises results fast (in as little as four hours).

The kit has everything you need. It includes an insert to treat the yeast infection, a tube of external cream, and four soothing wipes to help relieve itching and burning while the medication does its job. It can be used day or night as it uses a “less-mess ovule” that makes it easy to insert and keep the medication (miconazole nitrate) in place, right at the site of the infection.


Vagistat 3

For a simple, three-day yeast infection treatment, this one from Vagistat is the choice for many women. The combination pack includes three vaginal suppositories with disposable applicators to treat the infection internally and an external cream to provide relief from itching and burning in the short-term. The main ingredient is miconazole nitrate.

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NutraBlast Boric Acid Vaginal Suppositories

For a natural option, Boric acid has been found to be particularly effective in treating recurrent yeast infections. And women give this brand of suppositories that contain it top marks.

Each capsule contains 600 milligrams of boric acid, which is thought to support a woman’s pH balance and overall vaginal health. To use it, insert one capsule into the vagina (with or without an applicator) at bedtime for seven days.

Boric acid is, however, considered an alternative treatment. So, it’s a good idea to consult with your doctor before using it.


Yeastgard Advanced Homeopathic Capsules

If you’d rather take a pill than use creams and inserts, consider these capsules from Yeast Gard. They promise homeopathic relief from yeast infection symptoms and may even stave ​off future infections.

The capsules contain a mix of ingredients in a probiotic base and are intended to help the body rebalance its yeast on its own and heal. They can be used in conjunction with the company’s other products that deliver yeast infection treatment via suppositories.

Because it’s a homeopathic product, its effectiveness hasn’t been evaluated by the U.S. Food and Drug Administration. As always, please consult a medical professional before starting a supplement regime. 


Taro Clotrimazole 7 Vaginal Cream


Courtesy of Amazon

While it doesn’t have the name brand recognition, this seven-day Taro clotrimazole cream gets high marks for effectively treating vaginal yeast infections. It comes with seven days of cream you insert with an applicator as well as an external cream to relieve itching and external irritation. Similar to other products that contain clotrimazole, this one offers significant savings.


Vagisil Maximum Strength Instant Anti-Itch Vaginal Crème

While this cream from Vagisil won’t actually treat a yeast infection (you’ll need to find an additional method for that), but it does promise to deliver immediate relief from the itching and burning that typically comes along with one.

Its hypoallergenic formula is designed to help relieve the most painful burning and itching quickly without irritation. It can also be used for vaginal itching due to other causes, so it’s a good one to have on hand. 

The cream, which you apply with your finger, contains two external analgesics (benzocaine and resorcinol) and a blend of vitamins A, D, E, and aloe.

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Monistat 7-Day Vaginal Antifungal Pack


Courtesy of Target

While some prescription treatments should be avoided in pregnancy, experts say the active ingredient in Monistat (miconazole nitrate) is safe for mom and baby, with no risk of birth defects or other complications. It comes with seven disposable applicators to be used once a night at bedtime for a week.

Doctors say that longer treatments such as this are better during pregnancy than more concentrated formulas that offer treatment in just one or several days. This seven-day treatment provides the least concentrated dose of medication, but is still effective and doesn’t come with the burning and itching of stronger formulas.

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