Full-dose Blood Thinners Could Prevent COVID-Related Clotting in Hospitalized Patients

Anyone who has had COVID-19—even if it was a mild case—is at a higher risk of developing blood clots for months after recovery. If untreated, blood clot complications such as deep vein thrombosis and pulmonary embolism can cause serious damage to the heart or lungs.

A new study found that full-dose blood-thinning medications might help reduce the risk of blood clots in critically ill COVID-19 patients.

Typically, hospitalized COVID-19 patients might be given a relatively low dose of blood thinner to prevent blood clots, as a high dose might lead to severe bleeding. The study showed that a full-dose blood thinner did increase bleeding, but it didn’t increase the risk of death.

Ankit Shah, MD, an assistant professor at Rutgers New Jersey Medical School, told Verywell that the risk of life-threatening blood clots from COVID-19 appears to be lower now with more advanced treatment and milder variants.

He said the study findings suggested that patients in the ICU should be considered for full-dose anticoagulation, “but we need to individualize this decision based on the patient’s risk of clotting and bleeding.”

For instance, if a patient has a recent bleeding event, it may not be the best idea to give the full-dose blood thinner, Shah added.

How Can You Prevent Post-COVID Blood Clots? 

While hospitalized COVID-19 patients may receive blood thinners as part of their preventive treatment, most people won’t need this medication, Shah said.

“Only certain high-risk patients, such as those with previous blood clot, surgery, trauma, or immobilization should be considered for continued anticoagulation [upon discharge,]” he said.

According to Mark Loafman, MD, MPH, chair of the family and community medicine department at Cook County Health, said the rate of serious blood clot formation after a COVID-19 recovery seems to be decreasing over time, which is likely due to vaccinations.

A recent study published in JAMA Internal Medicine found that the risk of blood clots was substantially lower in people who were fully vaccinated.

After recovering from a COVID-19 infection, you can try to prevent blood clots by staying active and moving around.

“To decrease the risk of blood clot formation, we always encourage maintaining regular minimal activity like walking, stretching, light aerobic activity,” Loafman said. “In many cases, clot development is a gradual process, so any unexplained, unilateral leg or arm swelling should prompt a visit to your doctor or emergency department that same day.”

The information in this article is current as of the date listed, which means newer information may be available when you read this. For the most recent updates on COVID-19, visit our coronavirus news page.