Can You Get Pregnant If You Miss a Pill?

Inconsistent dosing can undermine the protective benefit

If you miss taking a birth control pill or take one at the wrong time, it does increase your chances of becoming pregnant. However, you shouldn't panic or assume that the protective benefit of treatment has completely disappeared. The drugs do have some "forgiveness" in that levels of the medication will remain in your blood even during a gap.

But it's important to remember that the pill is not infallible. While it is 99% effective in women who take the pill on time every day, that figure drops to 91% in women whose adherence is less than perfect.

Woman holding birth control pills, mid section

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If you miss more than one dose per cycle or pill pack, the risk of pregnancy can suddenly become very real.

How Birth Control Pills Work

Oral contraceptives work by providing your body with just enough hormones to suppress ovulation. When you take your pills as prescribed, your body will have a steady supply of medication to keep you from ovulating. We refer to this as maintaining the therapeutic drug level (or the level by which a drug remains effective).

To achieve the best results, you will need to take one pill at the same time every day. Missing or delaying doses allows the therapeutic drug level to drop.

  • Over the course of an hour, the drop may not be significant.
  • Over 24 hours, the drop could very well be significant.

Ultimately, there is a point by which drug levels may be so low as to allow ovulation to occur. This can vary from person to person with some women expelling the drugs more quickly from their system than others.

Can the Pill Terminate Pregnancy?

The pill does not terminate a pregnancy, the moment an egg is released, pregnancy can occur.

Reasons Why Birth Control Pills Fail

In addition to missed or late doses, there are other things that can undermine the effectiveness of oral contraceptives. Among them:

  • Progestin-only birth control pills (also known as the "mini-pill") have far less forgiveness than the regular pills which contain both progestin and estrogen.
  • Nausea, vomiting, or diarrhea can negate the effects of the pill by expelling too much of the active drug from the body.
  • Antibiotics can also interfere with the pill's mechanism of action. Rifampin (Rifadin) and, to a lesser extent, penicillin, amoxicillin, ampicillin, sulfamethoxazole/trimethoprim (Bactrim), tetracycline, minocycline, metronidazole (Flagyl), and nitrofurantoin all have known interactions with oral contraceptive medications.

In all such cases, complementary or back-up contraception should be considered, including the use of condoms, diaphragms, sponges, etc.

What to Do If You Miss a Dose

If you are late taking a birth control pill, don't panic. It's only human to forget every now and then, and there is no point in beating yourself up about it. Instead, try to identify why you missed the dose.

Was it caused by a change in your schedule? Was there an event or incident that distracted you? Did you rush off to work before realizing your mistake? By pinpointing the cause, you can find a way to avoid missing doses in the future, either by altering your dosing schedule or providing yourself helpful, daily reminders.

If you are late taking the pill, here is what you should do:

  1. Take a dose as soon as you remember. This may mean doubling the dose if you missed an entire day. (Read the packet insert for better clarity on how and when to double up or call your doctor's office for assistance.)
  2. Use a backup method of birth control to help decrease your risk of pregnancy.
  3. Make a notation detailing what caused you to miss the dose. Keeping a daily treatment diary is particularly useful if you are just starting out.
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Article Sources
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  3. Mccann MF, Potter LS. Progestin-only oral contraception: a comprehensive review. Contraception. 1994;50(6 Suppl 1):S1-195. doi:10.1016/0010-7824(94)90113-9

  4. Dickinson BD, Altman RD, Nielsen NH, Sterling ML. Drug interactions between oral contraceptives and antibiotics. Obstet Gynecol. 2001;98(5 Pt 1):853-60.


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