Urological Health Penis Health Erectile Dysfunction Can Xanax Cause Erectile Dysfunction? By Laura Dorwart Laura Dorwart Laura Dorwart is a health journalist with expertise in disability rights, mental health, and pregnancy-related conditions. She has written for publications like SELF, The New York Times, VICE, and The Guardian. Learn about our editorial process Published on March 09, 2022 Medically reviewed by Matthew Wosnitzer, MD Medically reviewed by Matthew Wosnitzer, MD LinkedIn Twitter Matthew Wosnitzer, MD, is a board-certified urologic surgeon and physician scientist. He specializes in male infertility. Learn about our Medical Expert Board Print Table of Contents View All Table of Contents Xanax and ED Sexual Side Effects Causes of ED Management Frequently Asked Questions Xanax (alprazolam) can cause sexual side effects, including low libido (sex drive) and erectile dysfunction (ED). Xanax is a prescription medication used to treat anxiety disorders, such as generalized anxiety disorder (GAD) and panic disorder. It is also sometimes used to treat insomnia, muscle spasms, and seizures. Xanax belongs to the benzodiazepine drug class, which works by slowing down central nervous system (CNS) activity. Some of the most common side effects of Xanax include drowsiness, dry mouth, irritability, dizziness, headache, and difficulty concentrating. This article will discuss why Xanax causes sexual dysfunction for some people, how to manage Xanax and ED, and more. ajr_images / Getty Images Does Xanax Cause ED? Many prescription medications used to treat mental health conditions have sexual side effects. Recent research shows that Xanax (alprazolam) has been linked to erectile dysfunction (ED). ED can involve difficulty getting or sustaining an erection, abnormal ejaculation, and delayed or diminished orgasms. In clinical trials, people who were taking Xanax for symptoms of panic disorder experienced sexual dysfunction. Of the people who took Xanax, 7.4% reported having sexual side effects compared to 3.7% of people who were given a placebo (an inactive pill). In another study, people with panic disorder symptoms experienced a reduced sex drive, orgasm dysfunction, and ED when taking Xanax. Results from a Boston Area Community Health Survey in 2013 also associated long-term benzodiazepine use with increased ED symptoms among people aged 30 to 79. Xanax Sexual Side Effects Xanax has been linked to a number of possible sexual side effects, including: Erectile dysfunction Anorgasmia (diminished ability to orgasm) Delayed ejaculation Low libido Orgasm dysfunction The risk of sexual side effects from Xanax may increase for people who take it more often, for a longer period of time, and/or at a higher dose. A 2018 case study revealed that higher doses of alprazolam could raise the risk for anorgasmia among male patients. The Science of Male Orgasms Causes of Erectile Dysfunction It’s not entirely clear why Xanax sometimes causes ED. However, researchers believe that the answer could be related to how the drug affects the central nervous system (CNS). Benzodiazepines like Xanax work by slowing down CNS activity and increasing the levels in the brain of certain neurotransmitters (chemicals that carry signals between nerve cells), specifically dopamine and gamma amino-butryric acid (GABA)—a neurotransmitter that acts as a sort of sedative. While this mechanism effectively reduces stress, it may have the same inhibitory effect on libido and sex drive. Low libido can lead to ED and other kinds of sexual dysfunction. Even if your ED symptoms started around the time you began taking Xanax, it’s possible that your symptoms are due to another physical or mental health condition. Other common causes for ED may include: Heart disease High blood pressure Thyroid conditions Diabetes Multiple sclerosis (MS) Low testosterone Taking other prescription medications Drug or alcohol use Stress Depression Relationship problems Lack of sleep Most people take Xanax to treat symptoms of anxiety and other mental health conditions. Because anxiety and depression have both been linked to (and can exacerbate) ED, it’s important to address your underlying conditions as well as any sexual side effects you might experience from Xanax. What Is GABA? Managing Erectile Dysfunction on Xanax There are several possible ways to manage Xanax-related sexual dysfunction, including: Lowering your dose: Under the supervision of your healthcare provider, you might be able to take a lower dose of Xanax to decrease the severity of sexual side effects. Taking Xanax less frequently: Chronic and frequent use of benzodiazepines is linked to higher rates of ED. Taking Xanax less often may improve your sexual functioning. Discuss your dosing schedule with your healthcare provider. Switching to another medication: Your healthcare provider might be able to prescribe another antianxiety medication with a lower risk of ED. Taking medications for ED: Taking prescription medications to treat ED may counteract the sexual side effects of Xanax. Treating underlying conditions: Treating the symptoms of underlying conditions, such as anxiety and depression, can improve your overall sexual health. Talk to Your Healthcare Provider If you experience ED or other sexual side effects while taking Xanax, talk to your healthcare provider. They may be able to prescribe another medication, lower your dose, or refer you to another specialist who can help. Summary Xanax (alprazolam) is a common prescription medication that belongs to the class of drugs known as benzodiazepines. Usually, Xanax is prescribed to treat anxiety disorders and panic disorder. It may also be prescribed to treat seizures, insomnia, and muscle spasms. Some people who use Xanax report experiencing sexual side effects. In addition to erectile dysfunction (ED), some people with Xanax experience reduced sex drive, anorgasmia, problems with ejaculation, and orgasm dysfunction. These sexual side effects may be due to the drug’s effects on the central nervous system. People who experience ED while taking Xanax should talk to their healthcare provider about how their treatment could be modified to reduce this side effect. A Word From Verywell If you are experiencing sexual side effects while taking Xanax, don’t be afraid to reach out to your healthcare provider. They can offer alternatives and other solutions to help you treat your condition while improving your sexual functioning. Frequently Asked Questions How does antidepressant medication cause erectile dysfunction? Antidepressant medications and other psychotropic drugs can cause erectile dysfunction (ED) by affecting the activity of hormones and neurotransmitters. For example, selective serotonin reuptake inhibitors (SSRIs) may cause sexual side effects due to the drug’s impact on serotonin, dopamine, and testosterone levels.Xanax (alprazolam), which is usually prescribed to treat anxiety, may cause ED and reduce sexual drive by slowing down central nervous system activity. What are the other side effects of Xanax? In addition to sexual side effects such as erectile dysfunction and low libido, Xanax can cause side effects like headache, drowsiness, irritability, difficulty concentrating, difficulty urinating, dizziness, nausea, constipation, and changes in appetite.More severe side effects may include difficulty breathing, skin rashes, problems with speech or coordination, seizures, and disorientation. If you have any of these side effects, seek medical attention immediately. Does Xanax lower testosterone? It’s unclear exactly how Xanax (alprazolam) affects testosterone levels, as research is limited. The only study found was an older one on rats that showed Xanax did not affect testosterone levels. 10 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Kupelian V, Hall SA, McKinlay JB. Common prescription medication use and erectile dysfunction: results from the Boston Area Community Health (BACH) survey. BJU Int. 2013;112(8):1178-1187. doi:10.1111/bju.12231 MedlinePlus. Alprazolam. MedlinePlus. Erection problems. Food and Drug Administration. Xanax label. Bella AJ, Shamloul R. Psychotropics and sexual dysfunction. Cent European J Urol. 2014;66(4):466-471. doi:10.5173/ceju.2013.04.art22 Kaufman KR, Coluccio M, Linke M, Noonan E, Babalola R, Aziz R. Alprazolam-induced dose-dependent anorgasmia: case analysis. BJPsych Open. 2018;4(4):274-277. doi:10.1192/bjo.2018.35 National Alliance on Mental Illness. Mental health medications: benzodiazepine-associated risks. Jarullah FA, Yaseen M, Abdullah H, Yaqoob S. Erectile dysfunction and associated anxiety and depression in male hemodialysis patients: a cross-sectional study at Karachi Institute of Kidney Diseases. Cureus. 2020;12(10):e11129. doi:10.7759/cureus.11129 Jing E, Straw-Wilson K. Sexual dysfunction in selective serotonin reuptake inhibitors (SSRIs) and potential solutions: A narrative literature review. Ment Health Clin. 2016;6(4):191-196. doi:10.9740/mhc.2016.07.191 Ottenweller JE, Tapp WN, Natelson BH. Effects of chronic alprazolam treatment on plasma concentrations of glucocorticoids, thyroid hormones, and testosterone in cardiomyopathic hamsters. Psychopharmacology (Berl). 1989;98(3):369-71. doi:10.1007/BF00451689 By Laura Dorwart Laura Dorwart is a health journalist with particular interests in mental health, pregnancy-related conditions, and disability rights. She has published work in VICE, SELF, The New York Times, The Guardian, The Week, HuffPost, BuzzFeed Reader, Catapult, Pacific Standard, Health.com, Insider, Forbes.com, TalkPoverty, and many other outlets. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit