First Aid What Causes Diaphoresis? Learn the causes of cold sweats By Rod Brouhard, EMT-P Rod Brouhard, EMT-P Facebook LinkedIn Twitter Rod Brouhard is an emergency medical technician paramedic (EMT-P), journalist, educator, and advocate for emergency medical service providers and patients. Learn about our editorial process Updated on October 04, 2022 Medically reviewed by Michael Menna, DO Medically reviewed by Michael Menna, DO Michael Menna, DO, is board-certified in emergency medicine. He is an attending emergency medicine physician at White Plains Hospital in White Plains, New York and also works at an urgent care center and a telemedicine company that provides care to patients across the country. Learn about our Medical Expert Board Print Table of Contents View All Table of Contents Emergency Symptoms Cold vs Typical Sweat Fight-or-Flight Shock Infection Syncope Severe Pain Heart Attacks Shortness of Breath Low Blood Glucose Cancer Frequently Asked Questions Diaphoresis is the medical term for cold sweats—sudden, whole-body sweating that doesn't come from heat or exertion. It can have many causes, ranging from typical life events to life-threatening medical emergencies. This article looks at emergency symptoms related to diaphoresis, conditions that may lead to diaphoresis, why, and what to do about it. Verywell / Cindy Chung Emergency Symptoms Symptoms that accompany cold sweats and may indicate a medical emergency include: Chest pain or pressurePain that radiates to the neck or armCyanosis (blue lips or fingers)Sudden rapid heartbeat or other heart rhythm changesWeak pulseRapid breathing, labored breathing, or shortness of breathWheezing or coughingNo response to asthma medicationsPale skinWeaknessDizzinessHigh or very low temperature with chillsCool, pale limbsLack of urineConfusion or lethargySkin rashNew injurySevere pain of unknown causeShakingAnxiety or irritability Call 911 if you or someone else has any of these symptoms. Cold Sweats vs. Typical Sweat Typical sweating is the body's way of cooling itself. It's triggered by heat from your environment or exertion that raises your body temperature. The cold sweats of diaphoresis are unrelated to these causes. Sometimes causes of diaphoresis are emergencies, like septic shock or a heart attack, while others are less serious or not cause for concern. Common causes of diaphoresis include: Fight-or-flight responseShockInfectionSyncope (fainting)Pain from injuriesHeart attackSevere shortness of breathLow blood glucose (sugar)Fear and anxiety Diaphoresis itself isn't a problem and it isn't treated directly. Instead, healthcare providers target the cause of cold sweats, such as treating an infection or providing pain management. Paying attention to other symptoms you may have can help you determine what steps you need to take to protect your health. Fight-or-Flight Response Anything that causes a fight-or-flight response to stress in the body can cause cold sweats. This includes fear, phobias, and anxiety. The fight-or-flight response is triggered when you encounter a situation your body sees as a threat. It allows you to either defend yourself or get away. This is probably the most common cause of diaphoresis. Symptoms When fight-or-flight kicks in, your body dumps the stress hormones adrenaline and cortisol into your blood. Then: Your blood pressure, heart rate, and breathing speed up.Blood sugar rises to give you quick energy.Your brain goes on high alert, paying attention to small details that it normally would filter out.Your muscles are tense and ready to respond.You have cold sweats. Causes When you're in fight-or-flight mode, the excess adrenaline in your system activates the sweat glands, causing diaphoresis. What to Do: Give It Time Once the cause of the fight-or-flight response is over, your body should return to normal after between 20 and 60 minutes. It may help to try calming your body through deep breathing or other relaxation methods. How to Stop a Panic Attack Shock Your body goes into shock when blood flow to the brain and other vital organs becomes dangerously low. That means the brain doesn't get enough oxygen and nutrients. Shock causes increasing body-wide stress. Symptoms Diaphoresis is a key symptom of this potentially life-threatening condition. Other symptoms include: A sudden, rapid heartbeat Weak pulse Rapid breathing (more than 20 inhalations per minute) Pale skin Feeling weak or dizzy when sitting up or standing Causes Shock is often caused by an injury, such as a car accident or traumatic fall. Some injuries may produce obvious blood loss, but others involve internal bleeding that you can't see. It can also be caused by: Heatstroke Allergic reactions (anaphylactic shock) Severe infection (septic shock, toxic shock syndrome) Poisoning Severe burns Damage to the nervous system (neurogenic shock) These causes change the way your body handles blood flow. For example, infection and severe allergies affect the blood vessels in a way that significantly lowers blood pressure. What to Do: Call 911 Shock is serious enough to warrant immediate medical attention. Call 911 for help if you suspect you or someone else is in shock. Until help arrives, lie flat on your back with your feet propped on something about 8 to 12 inches tall. That helps preserve blood flow to the brain and vital organs. Signs and Symptoms of Shock Infection The flu, COVID-19, and any other infection that causes a fever can lead to cold sweats. Sometimes they occur as a fever "breaks" or starts to go back down. In severe cases, the body may go into septic shock. Symptoms Common symptoms of infection include: FeverChills and cold sweatsCoughSore throatShortness of breathNasal congestionVomitingDiarrheaAbdominal painDiscoloration, pain, or swelling around wounds Symptoms of septic shock may be: High or very low temperature with chills and cold sweatsCool, pale limbsLightheadednessLittle or no urineLow blood pressure that may cause dizziness when standingHeart palpitationsRestlessness, agitation, confusion, or lethargyShortness of breathSkin rash or discoloration Causes Medical conditions that can lead to septic shock include: Pneumonia (infection in the lungs' air sacs) Urinary tract infection Bacterial infection in a cut or wound Gastrointestinal tract infection, such as appendicitis or E. coli Septic shock is most common in the very old, the very young, and people with a compromised immune system. What to Do: Call 911 or Make an Appointment Septic shock is always a medical emergency. It often requires time in an intensive care unit. If you suspect septic shock, call 911 or get to an emergency room right away. For an infection that causes cold sweats but not septic shock, make an appointment to see your healthcare provider soon or go to an urgent care facility. Be sure to stay hydrated, especially if you're sweating heavily and/or have a fever, vomiting, or diarrhea. Diaphoresis vs Hyperhidrosis Diaphoresis and hyperhidrosis aren't the same. Diaphoresis is a symptom of many conditions while hyperhidrosis is a medical condition that involves excessive and unpredictable sweating. It's believed to be caused by overactive sweat glands. Syncope Cold sweats may be a symptom of syncope, often called fainting or passing out. Symptoms When you have syncope, you briefly lose consciousness. This typically makes you fall to the ground (or slump, if you're sitting). Before you pass out, you may have symptoms of pre-syncope (the feeling you're about to faint). These can include: LightheadednessNausea"Grayed out" visionTrouble hearingHeart palpitationsWeaknessDiaphoresis With syncope, you may also experience: Nausea Vertigo Causes Syncope is caused by a sudden drop in blood pressure. This can be caused by: Slow, fast, or irregular heartbeats (arrhythmia) Low blood pressure, often after standing up Those changes in heart function and blood flow may be the result of: Heart conditions including aortic dissection and aortic valve stenosis Postural orthostatic tachycardia syndrome (POTS) Emotional shock Sudden, unexpected trauma, pain, or stress Standing up quickly ("head rush") Donating blood What to Do: Get Medical Attention If you've had syncope or pre-syncope for an unknown reason or due to trauma or a medical event, get medical attention right away. Fainting can lead to serious injuries. Get medical help for someone who gets hurt during an episode of syncope. If the reason for syncope is known and not serious (such as an emotional shock), lying on the back with the feet elevated can help. You should always let your healthcare provider know if you've had syncope or pre-syncope. Night Sweats Night sweats are a type of diaphoresis that may be tied to: Hormonal changes of menopause A thyroid disorder Cancers such as leukemia and lymphoma Severe Pain Severe pain from an injury, like a fracture or non-surgical amputation (losing a body part), can lead to cold sweats. Some medical causes of severe pain, such as kidney stones, can also cause diaphoresis. Symptoms The only consistent symptoms in this case are severe pain and cold sweats. Other symptoms will vary depending on what's causing the pain. In rare cases, severe pain can occur long after a head injury or spinal cord trauma. This is a symptom of complex regional pain syndrome (CRPS), and diaphoresis is a common feature. Other symptoms of CRPS include: Severe burning or aching painPain that increases with even a light touchSkin temperature fluctuating between hot and coldRapid hair and nail growthMuscle spasmsJoint painSkin that appears pale, discolored or mottled, thin, and shiny Causes The cause of diaphoresis in severe pain is similar to that of shock. CRPS may be caused by a problem with the immune system that leads to problems with nerves that control flood flow, temperature, and sensation. What to Do: Call 911 or Make an Appointment For a new serious injury or undiagnosed medical cause of severe pain, call 911. Once the severe pain is treated, cold sweats and other symptoms should diminish. If you suspect you may have CRPS, make an appointment with your healthcare provider. If the pain is from a diagnosed cause that isn't an emergency (such as cancer, a chronic pain condition, or a healing injury), treat your pain as directed by your healthcare provider. If you don't have the means to treat your pain, make an appointment to discuss pain management. What Is Complex Regional Pain Syndrome (CRPS)? Heart Attacks Cold sweats are a common sign of a heart attack (myocardial infarction). Symptoms Aside from diaphoresis, symptoms of a heart attack may include: Chest pain or pressurePain that radiates (spreads) to the neck or armShortness of breathNauseaVomitingDizzinessCyanosis (a blue tint to the lips or fingers)Changes to your heart rhythm Causes In a heart attack, blood flow to your heart muscle is interrupted. This triggers a stress response that leads to diaphoresis. What to Do: Call 911 A heart attack is a true emergency. Call 911 immediately. The faster that you act, the better your chances of limiting damage and having a better outcome. Taking a chewable aspirin while waiting for the ambulance may help prevent heart damage. Why to Take Aspirin During a Heart Attack Shortness of Breath Severe shortness of breath can lead to diaphoresis, among other symptoms. Symptoms Other signs of shortness of breath may include: Rapid breathingPursed-lip or tripod (leaned forward) breathingMental confusionWheezing or coughingFatigueAnxiety Causes When you're short of breath, it causes a lack of oxygen in the bloodstream. When your brain begins to crave oxygen, it sends your body into a stress response, similar to fight-or-flight or shock. What to Do: Call 911 or Treat Your Shortness of Breath Any time you have trouble breathing, it's a serious situation. Call 911 if: You don't know the causeHave a known cause that's an emergency (such as anaphylactic shock or a lung injury)Can't quickly get yourself breathing better If you have shortness of breath due to a known condition, such as asthma or chronic obstructive pulmonary disorder (COPD), follow your healthcare provider's instructions. If your usual treatments don't work, call 911. Causes and Treatments of Shortness of Breath Low Blood Glucose Hypoglycemia (low blood glucose/sugar) is a fairly common reason for cold sweats. It's seen most often in people with diabetes or prediabetes. Symptoms Other common symptoms of hypoglycemia include: Rapid heartbeatShakingNervousness or anxietyIrritability or confusionDizzinessHunger Causes Glucose is the brain's preferred source of energy, so it responds to low blood sugar as a serious threat. As with a lack of oxygen, this triggers a stress response that leads to diaphoresis. What to Do: Call 911 or Make an Appointment If someone with diabetes seems confused or has other symptoms of hypoglycemia, call 911 and get them something sugary to eat or drink. If you have symptoms of hypoglycemia but aren't diagnosed with a condition that can cause it, make an appointment with your healthcare provider. Symptoms of Hypoglycemia (Low Blood Sugar) Cancer Many types of cancer can cause diaphoresis, especially at night. They include: Lymphoma (non-Hodgkin or Hodgkin) Carcinoid tumors Leukemia Mesothelioma Bone cancer Liver cancer Any advanced cancer Symptoms Early cancer symptoms can vary greatly depending on the type, location, and stage of the tumor(s). Some common early symptoms may include: Fatigue that doesn't improve with rest Unintended weight loss of more than 10 pounds Loss of appetite Trouble swallowing Abdominal pain, nausea, and vomiting Unexplained swelling Lumps anywhere in the body Breast lumps or thickening tissues Pain with no known cause that doesn't go away or gets worse Changing moles Sores that don't heal Skin lumps that bleed or scale Jaundice (yellowing skin or eyes) Ongoing cough or hoarseness Unusual bleeding or bruising Changes in bowel habits (e.g., diarrhea, constipation) Abnormal appearing stools Pain when urinating, bloody urine, or frequent urination Headaches Vision or hearing problems Mouth sores, bleeding, pain, or numbness Causes In some cases, cancerous tumors trigger changes in the body that lead to diaphoresis. Some cancer treatments—including chemotherapy, radiation, hormone treatments, and some other medications—can also cause excessive sweating. So can morphine, which is sometimes used to treat cancer pain. Common problems associated with cancer that can cause cold sweats include: Infections Menopause (triggered by surgery or hormone therapy) Severe pain Poor mental health (anxiety, depression) Trouble sleeping Testicle removal (a common treatment for prostate cancer) What to Do: Make an Appointment While cancer is a serious and potentially life-threatening illness, it's not something you generally need emergency treatment for—especially if you're just noticing what could be early symptoms. If you're having concerning symptoms, make an appointment with your healthcare provider. Explain your symptoms and concerns and stress that you need to be seen soon. Early diagnosis can make for a better outcome. Similar to menopause, hormonal changes from breast cancer or breast cancer treatment may cause hot flashes and heavy sweating. Why sex hormone changes have this effect isn't yet understood. Summary Cold sweats are different from sweat in response to heat or exertion. They're called diaphoresis and they have many causes, such as a fight-or-flight response, low blood sugar, or life-threatening events like a heart attack or shock. Mechanisms that cause of diaphoresis include the body's response to stress, loss of blood, low blood pressure, and adrenaline directly stimulating the sweat glands. Emergency causes warrant a call to 911. For others, you may want to see your healthcare provider. Some causes, such as fight-or-flight, should go away quickly on their own. Frequently Asked Questions Why do I wake up in a cold sweat? So-called “night sweats” can be caused by the same conditions that bring on other cold sweats. Other possible causes include hormonal changes, depression, thyroid disease, or medication side effects. Learn More: Why Do I Sweat in My Sleep? Are cold sweats normal during drug withdrawal? Yes, especially during opiate and alcohol withdrawal. In severe cases, people need to be carefully monitored for life-threatening complications of drug withdrawal. Learn More: Stages of Alcohol Withdrawal 20 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. National Institutes of Health, National Cancer Institute. Fight-or-flight syndrome. Pennsylvania State University. SiOWfa16: Science in our world: Certainty and controversy. Bonanno FG. Clinical pathology of the shock syndromes. J Emerg Trauma Shock. 2011;4(2):233-43. doi:10.4103/0974-2700.82211 National Institutes of Health, U.S. National Library of Medicine: MedlinePlus. Shock. Centers for Disease Control and Prevention. Know the signs and symptoms of infection. National Institutes of Health, U.S. National Library of Medicine: MedlinePlus. Septic shock. 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Neuroendocrine responses to hypoglycemia. Ann N Y Acad Sci. 2010;1212:12-28. doi:10.1111/j.1749-6632.2010.05820.x Cancer Research UK. Causes of sweating. National Institutes of Health, U.S. National Center for Biotechnology Information. Hot flashes and night sweats (PDQ). National Institutes of Health, National Cancer Institute. Hot flashes and night sweats (PDQ)-Patient version. Whitaker K. Earlier diagnosis: the importance of cancer symptoms. Lancet Oncol. 2020;21(1):6-8. doi:10.1016/S1470-2045(19)30658-8 Grover S, Ghosh A. Delirium tremens: Assessment and management. J Clin Exp Hepatol. 2018;8(4):460-470. doi:10.1016/j.jceh.2018.04.012 Additional Reading Kyaw TH, Sullivan L, Klingsberg RC. A 45-year-old woman with 3 weeks of cough and night sweats. Chest. 2016 Mar;149(3):e87-90. doi:10.1016/j.chest.2015.08.014. By Rod Brouhard, EMT-P Rod Brouhard is an emergency medical technician paramedic (EMT-P), journalist, educator, and advocate for emergency medical service providers and patients. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit