Supplements Herbal Supplements What Is Coltsfoot? Traditionally Used for Sore Throat, Dry Cough, and Respiratory Conditions By Jennifer Lefton, MS, RD/N, CNSC, FAND Jennifer Lefton, MS, RD/N, CNSC, FAND Jennifer Lefton, MS, RD/N-AP, CNSC, FAND is a Registered Dietitian/Nutritionist and writer with over 20 year of experience in clinical nutrition. Learn about our editorial process Updated on March 22, 2023 Medically reviewed by Melissa Nieves, LND, RD Medically reviewed by Melissa Nieves, LND, RD Facebook LinkedIn Melissa Nieves, LND, RD, is a registered dietitian and licensed nutritionist who works as a bilingual telehealth dietitian. She founded the Fad Free Nutrition Blog and Nutricion al Grano websites and is based in Texas. Learn about our Medical Expert Board Print Verywell / Anastasia Tretiak Table of Contents View All Table of Contents Uses Side Effects Precautions Dosage Overdose Interactions Storing Frequently Asked Questions Sources & What to Look For Coltsfoot is a perennial plant that can grow up to 12 inches tall. The plant has golden-colored flowers that resemble dandelions. Coltsfoot originated in Europe and parts of Asia. The plant also grows throughout damp areas of North America and is known to flourish along roadsides and in meadows and hedgerows. Coltsfoot has been used as an herbal supplement in traditional Chinese medicine (TCM) and Western herbalism, primarily as a treatment for sore throat and chronic (long-term) coughs and other respiratory diseases. Coltsfoot's latin name, Tussilago farfara, is derived from the word "tussis," meaning cough, and "ago," meaning "to act on." Unlike drugs, dietary supplements are not regulated in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. When possible, choose a supplement tested by a trusted third party, such as U.S. Pharmacopeia (USP), ConsumerLab, or NSF International. However, even if supplements are third-party tested, they are not necessarily safe for all or effective in general. Therefore, it is important to talk to your healthcare provider about any supplements you plan to take and check in about potential interactions with other supplements or medications. Supplement Facts Active ingredient(s): Contains approximately 150 compounds, including sesquiterpenoids, triterpenoids, flavonoids, phenolic acids, etc.; oral coltsfoot contains pyrrolizidine alkaloids (PAs), which may be toxicAlternate name(s): Tussilago farfaraSuggested dose: No standard recommended dose Safety considerations: Considered mostly unsafe Uses of Coltsfoot Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider. No supplement is intended to treat, cure, or prevent disease. Coltsfoot is often mistaken for the dandelion plant. The flowers and leaves are the primary parts of the plant that are used for medicinal purposes, and the roots are usually avoided. Coltsfoot has been used in TCM as an antioxidant (to strengthen the immune system), an antitussive (to ease cough), an antimicrobial (to kill bacteria), and an anti-inflammatory agent (to lower inflammation). However, most studies involving coltsfoot have been done on animals and not on humans. There is not enough evidence to support the use of coltsfoot for these actions in humans. Additionally, the safety of coltsfoot taken orally has been questioned due to the presence of hepatotoxic pyrrolizidine alkaloids (PAs). PAs can severely damage the liver and lungs. Although coltsfoot has been widely used for several medical conditions, there is a lack of scientific evidence to back up most of the claims. What Are the Side Effects of Coltsfoot? Many side effect concerns are with oral use of coltsfoot due to its PA content. The primary side effect reported from this use of coltsfoot is liver toxicity. Other possible side effects include: Carcinogenicity: A substance that promotes carcinogenesis (the formation of cancer)Mutagenicity: A chemical or physical agent's capacity to cause mutations (genetic alterations), which is what is linked to the carcinogenesis of PAsSun sensitivity: Making you more susceptible to sunburn and sun damage of the skinAllergic reactions: Hives, skin rash, swelling, wheezing, shortness of breath, or more serious signs and symptoms like nausea and vomiting, severe trouble breathing, weak pulse, seizures, or loss of consciousness Always consult your healthcare provider first about supplement use. Precautions Coltsfoot is not generally considered safe for anyone. However, the herb should be especially avoided in the following populations: Infants or childrenPregnant peopleBreastfeeding peopleThose with liver problemsPeople with allergies to ragweed, chrysanthemums, marigolds, daisies, or related plants in the Asteraceae (Compositae) familyIndividuals with high blood pressure as coltsfoot may interfere with treatmentPeople with heart diseasePeople with bleeding disorders Dosage: How Much Coltsfoot Should I Take? Always speak with a healthcare provider before taking a supplement to ensure that the supplement and dosage are appropriate for your individual needs. There is insufficient clinical research data to support a recommended safe dosage of coltsfoot. The appropriate dose of any supplement, including coltsfoot, should be based on several factors such as weight, age, general health, and other factors. Although herbal products may be natural, that doesn't mean they are necessarily safe, particularly when taken in large doses. What Happens If I Take Too Much Coltsfoot? Taking too much coltsfoot may lead to liver damage and increase the risk of certain cancers. A study examined the toxic effects of plants containing PAs. The study reported that the toxic effects of some herbs—including coltsfoot—can cause acute liver disease, resulting in veno-occlusive disease (characterized by an enlarged liver) or, in some instances, liver cirrhosis. Cirrhosis is a serious condition in which the liver no longer functions properly due to long-term damage. The study also explains that some PAs, including those in coltsfoot, have shown genotoxic (causing genetic damage), mutagenic (causing gene mutations), teratogenic (affecting the normal development of the fetus in utero), and carcinogenic (cancer-causing) effects. The PA in coltsfoot has also reportedly caused veno-occlusive disease (a condition involving liver enlargement), which was reported in a newborn after the infant’s mother drank tea containing coltsfoot during pregnancy. The liver condition was said to result from the well-known hepatotoxins (substances that are toxic to the liver) contained in coltsfoot. Interactions There are no well-documented cases of coltsfoot interacting with other drugs or supplements. Coltsfoot may increase blood-clotting time and cause a higher risk of bruising and bleeding when taken with anticoagulants, such as Jantoven (warfarin) or aspirin. Anyone taking these or any other medications, supplements, or over-the-counter (OTC) drugs or preparations should consult their healthcare provider before taking herbal products. It is essential to carefully read the ingredients list and nutrition facts panel of a supplement to learn which ingredients and how much of each ingredient is included. Please review this supplement label with your healthcare provider to discuss any potential interactions with foods, other supplements, and medications. How to Store Coltsfoot If you have coltsfoot in your home, store it as directed on the packaging and ensure it is out of the reach of children and pets. Frequently Asked Questions Is coltsfoot safe to use in a tea for a child’s cough? No. Coltsfoot is never considered safe for use in infants or children. There is insufficient clinical research evidence that shows the safety or efficacy of the herb. Due to its well-known side effects, such as liver toxicity, do not give it to children. Can coltsfoot be used on the skin? Possibly. The flowers of the herb have been made into a poultice to treat some skin conditions. Still, there is insufficient scientific evidence from clinical research studies to back any claims of safety or efficacy in the topical use of coltsfoot. Always speak to your healthcare provider before using herbal remedies. Verywell / Anastasia Tretiak Sources of Coltsfoot & What to Look For Coltsfoot is commonly made into tea using the leaves or flowers of the plant. Other preparations include a topical flower compress to treat skin problems such as inflammation. Some people smoke the herb, suggesting that it is effective for respiratory disorders, but the evidence does not back up the safety or efficacy of smoking coltsfoot. In addition, the safe and effective use of coltsfoot in tea or to treat skin problems is not backed up by scientific evidence. Herbal supplements are not regulated as strictly as conventional drugs and food products in the United States. Therefore, you must do your due diligence to ensure you get a safe, hepatotoxic PA-free product. Dietary supplements sold in the United States are not required to state the amount of PAs they may contain. You should assume there are hepatotoxic PAs in any coltsfoot product unless stated otherwise. Avoid using coltsfoot products that are not certified and labeled as hepatotoxic PA-free. Summary Coltsfoot, also known as Tussilago farfara, is an herbal supplement marketed for antitussive, antimicrobial, and anti-inflammatory properties. However, limited human studies assessing the safety and efficacy of coltsfoot are available. Coltsfoot use also carries the risk of liver toxicity due to pyrrolizidine alkaloids in its products. The potential risks of coltsfoot outweigh the purported benefits. Always consult a healthcare provider before taking coltsfoot or any other herbal supplement. 9 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Chen S, Dong L, Quan H, et al. A review of the ethnobotanical value, phytochemistry, pharmacology, toxicity and quality control of Tussilago farfara L. (coltsfoot). J Ethnopharmacol. 2021 Mar 1;267:113478. doi:10.1016/j.jep.2020.113478 Bota VB, Neamtu AA, Olah NK, et al. A comparative analysis of the anatomy, phenolic profile, and antioxidant capacity of Tussilago farfara L. vegetative organs. Plants (Basel). 2022;11(13):1663. doi:10.3390/plants11131663 Chen T, Mei N, Fu PP. Genotoxicity of pyrrolizidine alkaloids. J Appl Toxicol. 2010;30(3):183-196. doi:10.1002/jat.1504 Moreira R, Pereira DM, Valentão P, Andrade PB. Pyrrolizidine alkaloids: chemistry, pharmacology, toxicology and food safety. Int J Mol Sci. 2018;19(6):1668. doi: 10.3390/ijms19061668 Denisow-Pietrzyk M, Pietrzyk Ł, Denisow B. Asteraceae species as potential environmental factors of allergy. Environ Sci Pollut Res Int. 2019 Mar;26(7):6290-6300. doi:10.1007/s11356-019-04146-w Tsai HH, Lin HW, Lu YH, Chen YL, Mahady GB. A review of potential harmful interactions between anticoagulant/antiplatelet agents and Chinese herbal medicines. PLoS One. 2013;8(5):e64255. doi: 10.1371/journal.pone.0064255 Seremet O, Olaru O, Maria Gutu C, et al. Toxicity of plant extracts containing pyrrolizidine alkaloids using alternative invertebrate models. The Journal of Molecular Medicine Reports. 2018;17(6): 7757–7763. doi:10.3892/mmr.2018.8795 Roulet M, Laurini R, Rivier L, Calame A. Hepatic veno-occlusive disease in newborn infant of a woman drinking herbal tea. J Pediatr. 1988;112(3):433-436. doi:10.1016/s0022-3476(88)80330-5 Dasgupta A, Sepulveda J. Accurate Results in the Clinical Laboratory: a Guide to Error Detection and Correction. Pages 75-92. Amsterdam: Elsevier; 2013. doi:10.1016/C2011-0-04380-6 Additional Reading Chen T, Mei N, Fu PP. Genotoxicity of pyrrolizidine alkaloids. Journal of Applied Toxicology.2010;30:183–196. doi:10.1002/jat.1504 Hirono I, Mori H, Culvenor CC. Carcinogenic activity of coltsfoot, Tussilago farfara. The Japanese Journal of Cancer Research. 1976;7(1):125-9. Seremet O, Olaru O, Maria Gutu C, et al. Toxicity of plant extracts containing pyrrolizidine alkaloids using alternative invertebrate models. The Journal of Molecular Medicine Reports. 2018;17(6): 7757–7763. doi:10.3892/mmr.2018.8795 By Jennifer Lefton, MS, RD/N, CNSC, FAND Jennifer Lefton, MS, RD/N-AP, CNSC, FAND is a Registered Dietitian/Nutritionist and writer with over 20 years of experience in clinical nutrition. Her experience ranges from counseling cardiac rehabilitation clients to managing the nutrition needs of complex surgical patients. Originally written by Cathy Wong Cathy Wong Cathy Wong is a nutritionist and wellness expert. Her work is regularly featured in media such as First For Women, Woman's World, and Natural Health. Learn about our editorial process See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? 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