CT Lung Cancer Screening

Lung cancer screening is an area that could make a big difference in the future of lung cancer. As Pap smears have decreased the risk of cervical cancer, and colonoscopies have resulted in a decline in deaths from colon cancer, it would be wonderful to have a screening tool to detect lung cancer in the earlier, more curable stages. At this time, too many lung cancers go undetected until they are at an advanced stage. Due to late detection, the overall survival rate for individuals newly diagnosed with lung cancer is a saddening 17 percent.

In the past, both chest x-rays and sputum cytology were evaluated as methods to detect lung cancer at an earlier stage, but neither of these procedures was found to improve long-term survival. Hence, routine chest x-rays are no longer used in smokers to screen for lung cancer.

Lung Cancer Screening Guidelines

The only procedure currently available for lung cancer screening before symptoms are present is a spiral (also called helical) CT scan. A spiral CT scan is similar to a conventional CT scan (the kind of CT scan most of us are familiar with) but is performed more quickly and results in less exposure to radiation. A recent large study found that high-risk individuals who underwent annual CT screening for 3 years had a 20 percent reduced risk of dying from lung cancer. This could translate to as many as 20 thousand lives being saved each year! High risk in this study was defined as people between the ages of 55 and 74 who had at least a 30 pack-year history of smoking. Despite this exciting news about a lower mortality rate, other issues need to be considered so that you can make an informed decision as you weigh benefits and risks for your particular situation. Issues to consider include:


For a screening technique to be adopted, it needs to be both sensitive, that is accurate in detecting disease in the early stages, but also specific, meaning it does not pick up too many insignificant findings. One problem with CT scans is that they can pick up spots in the lungs that are not cancerous. This can lead to unnecessary procedures to help diagnose findings and unnecessary surgeries. In one older study, 3 times as many lung cancers were found as predicted, but 10 times more surgeries were performed, and screening was not found to lower mortality. The recent National Lung Cancer Screening trial did show a lower risk of dying from lung cancer in high-risk individuals as noted above. Yet 40 percent of those who were screened were found to have abnormalities on screening that later turned out to be benign. In this case, the risk of false-positives (such as further radiological studies and possible biopsies) needs to be weighed against the benefit of detecting lung cancer in the earlier stages. In other words, if you decide to have lung cancer surgery, it's important to be prepared for a "scare" — the finding of something suspicious that later turns out to be nothing.


A recent study found that those who had abnormal findings on lung cancer screening did not experience appreciable anxiety. But of course, these are statistics, and individual people may feel very anxious when faced with evaluating an abnormal result The following article addresses this further:

Exposure to Radiation

While spiral CT screening for lung cancer results in less radiation exposure than conventional CT scans (the kind of CT Scans most of us are familiar with), the risk of developing lung cancer from radiation exposure can be significant, especially if scans are done yearly. In one study, a 5.5 percent increase in lung cancer risk was caused by yearly screening. This means that to justify screening, it would need to increase survival by more than 5.5%. There may also be an increase in breast cancer rates in women since radiation is directed at the chest.

The Cost

Another determinant in evaluating a screening test is whether it is cost-effective. This involves looking at the cost of screening versus the effect of screening (the number of years of life saved,) and is a current area of controversy. The Affordable Care Act requires that private insurers cover procedures with a grade of B or higher as determined by the United States Preventive Services Task Force (USPSTF.) A grade of "B" means that the USPSTF recommends the procedure and that there is high certainty that the net benefit is moderate. Medicare now covers screening for those who meet the criteria. 

Smoking Cessation

One benefit of screening that was found recently is an increased rate of smoking cessation among certain people who have undergone screening. People appear to be more likely to kick the habit if they have major abnormalities on screening whether or not these are suspicious for lung cancer.

Is It Right for Me?

Lung cancer screening remains an individual decision that should be discussed with your healthcare provider, who can assist you in weighing the risks and benefits of the procedure. Just as screening may be indicated for some people who do not meet the criteria (due to occupational exposures, asbestos exposure, radon exposure, etc.,) not everyone who meets the criteria is an ideal candidate for screening.

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