Brain & Nervous System Migraines Treatment Migraine Surgery Options These may be considered when other treatments have been unsuccessful By Colleen Doherty, MD Colleen Doherty, MD Colleen Doherty, MD, is a board-certified internist living with multiple sclerosis. Learn about our editorial process Updated on March 16, 2021 Medically reviewed by Sarah Rahal, MD Medically reviewed by Sarah Rahal, MD LinkedIn Sarah Rahal, MD, is a double board-certified adult and pediatric neurologist and headache medicine specialist. Learn about our Medical Expert Board Print Table of Contents View All Table of Contents How It Works Indications Nerve Decompression Efficacy Side Effects Surgical treatment has been used as a strategy for migraine prevention. While it may work for some people, surgery is not the right treatment for everyone, and there are no reliable criteria to predict whether you will have a good response to such a procedure. That said, there is some evidence suggesting that surgery may be beneficial for people with intractable or refractory migraines (those that do not improve with medical or alternative treatment). Migraine surgery is intended to be a one-time procedure, with the goal of alleviating the need to use acute migraine medications and chronic prophylactic medications. More than one type of technique has been proposed with the goal of “deactivating trigger sites.” In other words, those procedures aim to release peripheral nerves in the head and neck that are believed to be compressed, triggering the migraines. seb_ra / Getty Images How It Works Migraine surgery is based on the same principles as other interventional techniques used in migraine prevention. Injections of pain medications and muscle relaxers to the neck or head muscles are believed to alleviate muscle contraction and pain and to release nerve pressure. Botulinum toxin (Botox), a potent muscle paralytic, has also been used in migraine prevention. There is only limited evidence that either nerve compression or muscle spasm are involved in migraines. Nevertheless, these techniques seem to be effective for some people, suggesting that there is still a lot that the medical community needs to learn about migraines. The theory behind migraine surgery is that if botulinum toxin can temporarily prevent migraines by transiently decompressing nerves through muscle relaxation, then surgical removal of the offending muscles would mimic these effects permanently—or at least for a longer period of time. Prior to surgery, you may receive treatment with botulinum toxin. Some surgeons use this as a way to pinpoint the right location for migraine surgery. Plastic surgeons have observed that the surgical techniques used in migraine surgery are very similar to those used in facial cosmetic surgery. In fact, plastic surgeons suggest that procedures intended for rejuvenation of the face may reduce migraines as well. Indications In general, surgery is considered for people who have not improved with migraine medication or who experience intolerable side effects from such drugs. There have been some attempts to identify factors that can be predictors of improvement with migraine surgery. Some healthcare providers suggest that people whose migraines improve in response to botulinum toxin injections may also improve with other procedures. Nerve Decompression Migraine surgery involves nerve decompression through subtotal resection (partial removal) or complete resection of specific muscles or adjacent anatomy. A blood vessel can compress a nerve, causing nerve sensitivity. In such instances, the blood vessel can be gently "moved" to alleviate the physical pressure. The surgery is achieved by transecting muscles or other structures that may be compressing the nerve. Efficacy There is growing evidence that migraine surgery may work for some people. A number of small research studies have shown that some participants with refractory migraines may experience a greater than 50% reduction in migraine frequency, with a decreased need for medication for at least a few years after surgery. But one of the leading concerns in assessing these results is that migraine surgery is a type of procedure that is prone to inducing a placebo response. This refers to an improvement in symptoms from the inherent bias and psychological effect of undergoing treatment, rather than from the treatment itself. Also, reports suggest that even among research participants who are carefully selected for surgery, the success rate is quite variable. So, it is quite possible that you might not experience any improvement in your migraines after having this procedure. In addition, many of the studies have shown flaws in their design, prompting the American Headache Society to recommend against the use of migraine surgery outside of a clinical trial. Side Effects There are few side effects and adverse events reported with this type of surgery, but negative outcomes can occur. The most common side effects include nasal discharge, dryness of the nose, and scalp itching. Complications including infection, weakness or paralysis of the muscles, or post-operative scarring may occur. A Word From Verywell Migraines, especially refractory migraines, can have a major impact on your quality of life. Surgery is a potential—but not yet proven—treatment option for migraine prevention. Be sure to talk with your healthcare provider about all of your migraine-prevention options (lifestyle strategies, complementary and alternative therapies, and medication) and whether or not participating in a trial where surgery is being studied as a treatment for chronic migraine may be right for you. Migraine Doctor Discussion Guide Get our printable guide for your next doctor's appointment to help you ask the right questions. Download PDF Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Sign Up You're in! Thank you, {{form.email}}, for signing up. There was an error. Please try again. Can Acupuncture Help Migraines? 11 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Bertozzi N, Simonacci F, Lago G, Bordin C, Raposio E. Surgical therapy of temporal triggered migraine headache. Plast Reconstr Surg Glob Open. 2018 Dec;6(12):e1980. doi:10.1097/GOX.0000000000001980 American Migraine Foundation. Botox for migraine. Blake P, Burstein R. Emerging evidence of occipital nerve compression in unremitting head and neck pain. J Headache Pain. 2019 Jul;20(1):76. doi:10.1186/s10194-019-1023-y Jose A, Nagori SA, Roychoudhury A. Surgical management of migraine headache. J Craniofac Surg. 2018 Mar;29(2):e106-e108. doi:10.1097/SCS.0000000000004078 Gfrerer L, Guyuron B. Interface between cosmetic and migraine surgery. Aesthetic Plast Surg. 2017 May;41(5):1096-1099. doi:10.1007/s00266-017-0896-x Lee M, Monson MA, Liu MT, Reed D, Guyuron B. Positive botulinum toxin type a response is a prognosticator for migraine surgery success. Plast Reconstr Surg. 2013 Apr;131(4):751-757. doi:10.1097/PRS.0b013e3182818b7f Sanniec K, Borsting E, Amirlak B. Decompression-avulsion of the auriculotemporal nerve for treatment of migraines and chronic headaches. Plast Reconstr Surg Glob Open. 2016 Apr;4(4):e678. doi:10.1097/GOX.0000000000000663 Guyuron B, Kriegler JS, Davis J, Amini SB. Five-year outcome of surgical treatment of migraine headaches. Plast Reconstr Surg. 2011 Feb;127(2):603-608. doi:10.1097/prs.0b013e3181fed456 Gfrerer L, Hulsen JH, Mcleod MD, Wright EJ, Austen WG. Migraine surgery: an all or nothing phenomenon? prospective evaluation of surgical outcomes. Ann Surg. 2019 May;269(5):994-999. doi:10.1097/SLA.0000000000002697 Loder E, Weizenbaum E, Frishberg B, Silberstein S. Choosing wisely in headache medicine: the American Headache Society's list of five things physicians and patients should question. Headache. 2013 Oct;53(10):1651-169. doi:10.1111/head.12233 Mathew PG. A critical evaluation of migraine trigger site deactivation surgery. Headache. 2014 Oct;54(1):142-152. doi:10.1111/head.12218 Additional Reading American College of Surgeons. Definition of surgery legislative toolkit. Lee M, Erickson C, Guyuron B. Intranasal pathology in the migraine surgery population: Incidence, patterns, and predictors of surgical success. Plast Reconstr Surg. 2017 Jan;139(1):184-189. doi:10.1097/PRS.0000000000002888. By Colleen Doherty, MD Colleen Doherty, MD, is a board-certified internist living with multiple sclerosis. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit