Lupus Living With Donating Blood With Lupus Eligibility and Other Opportunities for Giving Back By Jeri Jewett-Tennant, MPH linkedin Jeri Jewett-Tennant, MPH, is a medical writer and program development manager at the Center for Reducing Health Disparities. Learn about our editorial process Jeri Jewett-Tennant, MPH Medically reviewed by Medically reviewed by David Ozeri, MD on April 07, 2020 linkedin David Ozeri, MD, is a board-certified rheumatologist. He is based in Tel Aviv, Israel, where he does research at Sheba Medical Center. Previously, he practiced at New York-Presbyterian Hospital. Learn about our Medical Review Board David Ozeri, MD Updated on October 07, 2020 Print Table of Contents View All Table of Contents Donation Eligibility Differing Guidelines Plasma Donation Studies Before You Donate If you have lupus (systemic lupus erythematosus or SLE) and want to donate blood, it's important to know that some organizations and blood banks will accept your donation whereas others will not. And even when lupus doesn't automatically disqualify you, eligibility criteria usually require that the disease be inactive or in remission. Potential risks to you also need to be considered, and you and your physician should discuss whether donating is a good idea for you. While it can be disappointing to find out you can't help people by giving blood, keep in mind that you can "give back" in many other ways. BSIP/UIG / Getty Images Blood Donation Eligibility Whether you can donate blood with lupus depends not only on the status of your condition but on where you choose to donate blood. Blood banks can vary considerably in their requirements and guidelines so that you may be able to donate somewhere even if you are told you are ineligible at one organization. It may take some legwork to find those who will accept our blood. There are also some reasons why people with lupus may not be able to donate blood regardless of the organization. Different Organizations, Different Guidelines Each blood bank and donation service has its own requirements for blood donations. Accepting Donations Organizations that accept blood from people with lupus include: The American Red Cross: Thanks to a policy change, this organization will accept your donation as long as: Your disease is inactive or in remissionYou're healthy at the time of the donation Memorial Sloan Kettering Cancer Center: Only if you're asymptomatic The National Health Service in the U.K.: If you haven't required treatment to suppress the disease in the past 12 monthsAND the condition has not affected your heart Not Accepting Donations Organizations that don't accept blood from people with lupus include: The National Institutes of HealthProvidence HealthAustralian Red Cross The organizations disqualify people with autoimmune disease in general. The Australian Red Cross claims it's concerned not only about the risk to the person receiving the blood, but about the potential for negative impact on the person with lupus. Guidelines are Subject to Change Just as the American Red Cross changed its eligibility requirements so that people with inactive lupus may give blood, other organizations may do so as well. Be sure to check the latest guidelines if you're interested in donating. Restrictions to Donating Blood With Lupus In addition to general guidelines that limit who can donate blood (such as those with HIV infection and more), some conditions that will disqualify people with lupus from donating blood at any blood bank or organization. Donating Blood With Lupus You can't donate blood if you have lupus plus any of the following:AnemiaAbnormal liver function tests (liver dysfunction)If the disease is active (not in remission)If you are taking some medications, including methotrexate, CellCept (mycophenolate mofetil), and biological agents (such as Benlysta (belimumab)If you aren't feeling well in any wayIf you have a fever The reasons for these restrictions is again two-fold. Doctors don't know how donating blood could affect you nor how exposure to components in your blood may affect the person who receives it, especially if that person is very ill or has a suppressed or compromised immune system. Plasma Donation and Lupus Since antibodies found in the blood are the primary cause for concern surrounding blood donations from people with lupus, plasma donation is usually discouraged. Red blood cells and platelets from people with lupus are generally considered "safe." Bone Marrow Donation and Lupus Having lupus, even in remission, is usually a contraindication for bone marrow donation. The organization Be the Match excludes people with an autoimmune disease other than stable autoimmune thyroid disease. Organ Donation and Lupus People with lupus may or may not be able to donate organs. The only two absolute contraindications are HIV infection and Creutzfeldt-Jacob syndrome. With lupus, problems with blood clots (antiphospholipid syndrome) would be one reason why doctors may think twice. In many cases, the benefits (saving a life) may easily outweigh the potential risks. Can You Catch Lupus From Another Person? Another Way to Help: Lupus Plasma Donation Studies Even if you can't donate plasma to help someone in need, there is another option for people with lupus. Several organizations ask for plasma donation from people with lupus in order to study the disease. Many of these are paid plasma donation studies, so those who are disappointed that they can't "give back" by donating blood could actually give back in two ways; their donation could further study on lupus, and they could use the monetary aspect to assist people struggling with their health (and life) in other ways. Before You Donate Before deciding whether to donate, it's important to consider whether it's right for you. Because you you can help or give back in other ways, you don't need to risk your health to do so. Possible Risks Potential risks of donating blood could include worsening of your disease, depending on what factors set off your lupus flares. If you have fatigue associated with your disease, donating blood could make it worse. It may also exacerbate lupus-related heart issues. Possible Benefits Against the risks to weigh are possible benefits. Due to inflammation in blood vessel walls or through triggering blood clots, lupus may increase the risk of strokes over the long run. Studies have found that people who regularly donate blood have a lower risk of stroke and heart disease. Heart Issues Associated with Lupus While you hear more about anemia (low iron levels), iron overload can also be a problem. In fact, "bloodletting" or regular removal of blood such as with blood donation (therapeutic phlebotomy) is a treatment for those with hemochromatosis. Making a Decision If you meet the criteria to donate, talk to your doctor first. Even if you are in remission and your disease is inactive, they may have some specific reasons why you should not donate. If you're disappointed, they will probably have some idea where you can use your desire to help others in a different way. Before working on behalf of others, however, make sure you are living and coping with your lupus as well as possible. People who take care of themselves first are better able to help others. A Word From Verywell If you are able to donate, it is a noble endeavor, as one blood donation can help save up to three lives. According to the Red Cross, every two seconds someone in the U.S. needs blood and only 5% of the eligible population donates in a given year. There's no blood substitute and donors are the only sources of blood. Donated blood is used not only in emergencies but also for people who have cancer, blood disorders such as anemia, and many other illnesses. Even so, many organizations do not allow people with lupus to donate, and if they do, the guidelines can significantly limit who may give blood. Unlimited ways of helping others exist, however, including becoming an advocate. Was this page helpful? Thanks for your feedback! Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Sign Up You're in! Thank you, {{form.email}}, for signing up. There was an error. Please try again. What are your concerns? Other Inaccurate Hard to Understand Submit Article Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. American Red Cross. Eligibility Criteria: Alphabetical. https://www.redcrossblood.org/donate-blood/how-to-donate/eligibility-requirements/eligibility-criteria-alphabetical.html