What Is Estroven?

A Dietary Supplement for Symptoms of Menopause

Estroven is the brand name of a line of dietary supplements that contains a combination of herbal extracts, soy isoflavones, vitamins, and minerals. Since 1997, Estroven products have been advertised as having the ability to ease some of the most frequently experienced symptoms of menopause.

Two main ingredients are found in all Estroven products. One is black cohosh root, a plant found in North America that contains fukinolic acid. Soy isoflavones derived from soybean plants are the other component (ingredient).

This article discusses menopause and its symptoms. It explains how Estroven products may help people during menopause and its possible side effects.

black cohosh
Verywell / Gary Ferster

Dietary supplements are not regulated in the United States, meaning the FDA does not approve them for safety and effectiveness before products are marketed. When possible, choose a supplement that has been tested by a trusted third party, such as USP, ConsumerLabs, or NSF. However, even if supplements are thir0party tested, that doesn't mean that they are necessarily safe for all or effective in general. It is important to talk to your healthcare provider about any supplements you plan to take and to check in about any potential interactions with other supplements or medications.

Supplements Facts

  • Active Ingredients(s): Black cohosh, soy isoflavones
  • Alternate Name(s): Estroven Maximum Strength
  • Legal Status: Supplement
  • Suggested Dose: Suggested dosages are listed on each product package for different formulations.
  • Safety Considerations: Allergies, pregnancy, breastfeeding, and liver disorders.

Uses of Estroven

Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietician, pharmacist, or doctor. No supplement is intended to treat, cure, or prevent disease.

Menopause

After the final menstrual period, which occurs in people designated female at birth around age 45 to 55, the next part of the reproductive life cycle, called menopause, begins. Estroven is typically used for symptoms of menopause. Symptoms may include hot flashes, vaginal dryness, emotional symptoms, and sleep changes.

Most people enter menopause due to estrogen and other hormone levels in the body naturally decreasing with age. They also may experience premature menopause, which causes these changes earlier in life because of a health condition, medication, or surgery. Removal of the ovaries, or damage caused by chemotherapy, may also cause early menopause. An Estroven formula for pre-menopausal symptoms also exists.

Menopause symptoms are sometimes treated with hormone replacement therapy (HRT). Clinical studies about the effects of black cohosh on menopause symptoms have shown mixed results.

Soy isoflavones, another component found in Estroven, have also been believed to relieve menopause symptoms. Some clinical data suggest that soy isoflavones reduced menopausal symptoms such as hot flashes, bone health, and lipids. This data is not enough to identify who would benefit from the use of soy isoflavones.

More research is needed to determine if these supplements are safe and effective for treating menopause.

What Are the Side Effects of Estroven?

Information about the side effects of Estroven as a combination product is lacking in clinical study data. There are some known side effects of black cohosh and soy isoflavones, components (ingredients) of Estroven.

Common Side Effects

Most side effects of products containing black cohosh are mild. Black cohosh side effects include:

  • Stomach upset
  • Rash
  • Cramping
  • Headaches
  • Vaginal spotting or bleeding

Potential soy side effects include:

  • Changes in thyroid function
  • Changes in digestion (constipation, diarrhea)
  • Impact on hormone-sensitive cancers (ex., breast cancer)

Severe Side Effects

There are no reported severe side effects of Estroven. However, there are instances where black cohosh may cause liver damage. These cases are rare, and it cannot be sure that black cohosh caused the liver disorder alone.

Suppose you are taking prescription medications or receiving care for a disease, such as chemotherapy for cancer. In that case, you should tell your healthcare provider before taking this or any other herbal supplement.

Precautions

Estroven contains black cohosh. Considering this, there are some precautions to be aware of when using Estroven as a supplement.

Black cohosh is not recommended for use by pregnant or breastfeeding persons. People who are pregnant should speak with their healthcare provider before using Estroven.

Anyone who has an allergy to the ingredients of Estroven should not use it.

It's important to remember that the health benefits and safety of Estroven remain unproven by research studies, the results of which remain mixed.

The U.S. Pharmacopeia recommends that people with diseases or conditions affecting the liver ask their healthcare provider before taking any supplements that have black cohosh in them.

Use caution with Estroven if you take certain medications like blood-thinners, thyroid medicines, or MAOIs.

Dosage: How Much Estroven Should I Take?

Always speak with a healthcare provider before taking a supplement to unsure that the supplement and dosage is appropriate for your individual needs.

Estroven is a dietary supplement that comes in the form of a capsule or caplet. It can be taken daily with or without food. The best time to take Estroven is with a meal; food may help you to avoid mild stomach upset.

Suggested dosages are listed on each product package for different formulations. Follow the instructions on the supplement packaging. To ensure you take the correct dose for your individual needs, consult with your healthcare provider.

Estroven products do not require a prescription and are available over the counter at most pharmacies and major retailers throughout the United States. The products can also be purchased online.

What Happens If I Take too Much Estroven?

Using Estroven as recommended on the product packaging is the safest way to use this supplement. There are no data on the effects of higher doses than suggested.

The effects of high doses of Estroven are unknown and should be avoided.

Interactions

Estroven is comprised of many products. These products may interact with other supplements, herbs, and medications. Reviewing the use of Estroven with your healthcare provider is best.

Blood-thinning medications: Estroven may interact with blood-thinning medications such as Jantoven (warfarin).

Monoamine oxidase inhibitors (MAOIs): The soy isoflavones in some Estroven formulations may interact with monoamine oxidase inhibitors (MAOIs).

Thyroid medications: Estroven may interact with thyroid medications such as Synthroid (levothyroxine).

It is essential to carefully read a supplement's ingredient list and nutrition facts panel to know which ingredients and how much of each component is included. Review this supplement label with your healthcare provider to discuss potential interactions with foods, other supplements, and medications.

How to Store Estroven

When storing Estroven it is best to follow the package recommendations. Storage and disposal instructions should be provided on the product packaging.

In general, it is safe to store supplements in a cool, dry, dark place.

Similar Supplements

There are other supplements available that tout relief of menopausal symptoms. Just as Estroven these supplements are a formulation of several products.

There are a few herbs that have been studied for their effects on menopause symptoms, such as:

Supplements that contain these herbs or a combination of these and other products, are used for the relief of menopausal symptoms. Examples of such supplements are:

  • Swiss Natural HRT
  • Promensil
  • Remifemin

Frequently Asked Questions

  • Are there other supplements for menopause besides Estroven?

    Yes. Some products used to treat menopause symptoms include evening primrose oil, red clover, and flax seeds. In most cases, the research is mixed on how effective they are. It's a good idea to talk to your healthcare provider about taking them.

  • Can I take Estroven if I am allergic to soy?

    Probably not. All Estroven products but one contain soy isoflavones that could provoke a reaction in people with soy allergies or sensitivities. Talk to your healthcare provider before taking any Estroven product if you're allergic to soy.

  • Are Estroven and estrogen the same thing?

    No. Estroven is an over-the-counter nutritional supplement containing herbs that may help relieve common menopause symptoms. Estrogen is a hormone produced by the body or taken as a prescription medication.

Sources of Estroven & What To Look For

Estroven is a readily available supplement used for the relief of menopausal symptoms. It can be found in drug stores, and grocery stores, and it is available online.

Estroven Supplements

The Estroven line of supplements contains products of differing strengths and formulations. These supplements are available in caplet or capsule form.

Summary

Some supplements, including Estroven products, are designed to relieve menopause symptoms. They contain black cohosh root and other ingredients, depending on the formula.

These supplements may ease symptoms, such as night sweats or mood swings, but the benefits remain unproven. There is not enough data to confirm they are safe or effective.

Estroven products, and especially their black cohosh and soy ingredients, also may cause side effects or possible drug interactions (ex., thyroid medicines, MAOIs, blood-thinning medications). Estroven should not be taken without guidance from a healthcare provider.

Hot flashes and other symptoms of menopause are common. Supplements like Estroven may help, but be sure you know what you're taking and if it's safe for you.

10 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. Croden J, Ross S, Yuksel N, Sydora BC. A survey of the availability in Canadian pharmacy chains of over-the-counter natural health products for menopause symptoms. BMC Complement Altern Med. 2015;15:86.

  2. U.S. Department of Health and Human Services. Black cohosh. National Center for Complementary and Integrative Health. 2022.

  3. Muqeet Adnan M, Khan M, Hashmi S, Hamza M, AbdulMujeeb S, Amer S. Black cohosh and liver toxicity: is there a relationship? Case Rep Gastrointest Med. 2014;2014:860614. doi:10.1155/2014/860614.

  4. Dohou J, Mouret-reynier MA, Kwiatkowski F, et al. A retrospective study on the onset of menopause after chemotherapy: Analysis of data extracted from the Jean Perrin Comprehensive Cancer Center Database concerning 345 young breast cancer patients diagnosed between 1994 and 2012. Oncology. 2017;92(5):255-263. doi:10.1159/000455049

  5. Francene MSteinberg, Michael J Murray, Richard D Lewis, et al. Clinical outcomes of a 2-y soy isoflavone supplementation in menopausal womenThe American Journal of Clinical Nutrition. 2011;93(2): 356–367, doi.org/10.3945/ajcn.110.008359

  6. National Institutes of Health. Soy.

  7. American Association of Family Physicians. Soy: A Complete Source of Protein.

  8. US Department of Health and Human Services. Black Cohosh. National Institutes of Health Office of Dietary Supplements. 2022.

  9. Alliance for Clinical Trials in Oncology. Phase III, randomized, placebo-controlled, double-blind trial of flaxseed for the treatment of hot flashes. Published 2017.

  10. Mohapatra S, Iqubal A, Ansari MJ, et al. Benefits of black cohosh (Cimicifuga racemosa) for women health: an up-close and in-depth review. Pharmaceuticals. 2022;15(3):278.

Additional Reading

By Dawn Sheldon, RN
Dawn Sheldon, RN, is a registered nurse and health writer. She is passionate about sharing her knowledge and empowering others.