Surgery Plastic Surgery Facial Procedures Print Guide to 7 Facial Wrinkles Smoothed by Botox By Naveed Saleh, MD, MS Updated July 05, 2019 Medically reviewed by a board-certified physician More in Plastic Surgery Facial Procedures Planning Your Surgery Reconstructive Surgery Liposuction Tummy Tuck (Abdominoplasty) More Body Procedures Breast Surgery Aging is an inevitable result of living, and wrinkles are a sign of aging. As we age, the muscle tone of our facial muscles increases. This increase in muscle tone along with decreased collagen metabolism—collagen is a component of the dermis, or the lower layer of skin that lies above the muscle—results in wrinkles. There's nothing wrong with wrinkles, and some people celebrate their wrinkles as evidence of a full life. Okay, probably no one celebrates her wrinkles; however, some people certainly don't mind wrinkles and don't want to spend money or time smoothing them out. Other people, however, desire to rid themselves of wrinkles. In addition to certain lifestyle modifications like avoidance of sun exposure and smoking cessation, there are numerous noninvasive treatments for wrinkles including laser, chemical peeling and injection of botulinum toxin (think Botox or Dysport). Injection with botulinum works best with dynamic wrinkles or wrinkles that appear after the formation of facial expressions like a smile or a frown. Conversely, static wrinkles remain while your face is relaxed and are best treated with a combination of botulinum toxin and dermal fillers. In other words, recalcitrant rhytides (medical jargon for wrinkles) need filler, too. Here are seven different facial wrinkles treated by injection with botulinum toxin. 1 Glabellar Lines Motortion / Getty Images Treatment of glabellar lines is the most common cosmetic use of botulinum toxin. The glabella is a patch of skin between the eyebrows and above the nose. 2 Crow's Feet Veronique Beranger / Getty Images Crow's feet (AKA periorbital lines or lateral canthal lines) are wrinkles that branch from the outer corners of the eyes while smiling. Of note, crow's feet that are static thus occurring in both the presence and absence of smiling. They are principally caused by photoaging—making them more resistant to treatment with Botox. 3 Forehead Wrinkles Frederick Bass / Getty Images The relatively large facial muscle that overlies the forehead is called the frontalis muscle. When the frontalis muscle contracts, the brow raises and forehead lines appear. 4 Bunny Lines Nico Kai / Getty Images Bunny lines occur on the bridge of the nose. They can become more prominent after botulinum toxin treatment for glabellar lines or crow's feet. Thus, people who have Botox treatment for glabellar lines or crow's feet often return for treatment of bunny lines, too. 5 Lipstick Lines Simon Winnall / Getty Images Perioral or lipstick lines are vertical wrinkles above the upper lip. The formation of lipstick lines is likely multifactorial and photoaging, hereditary factors, puckering and smoking all contribute. 6 Marionette Lines Westend61/Getty Images Marionette lines are vertical wrinkles that originate at the corners of the mouth and branch downwards towards the chin. (These lines resemble the borders of the jaw segment of a marionette.) Marionette lines are usually treated with both botulinum toxin and dermal fillers. 7 Chin Dimpling Tim Flach/Getty Images Chin dimpling gives the chin an orange-peel (peau d'orange) appearance. As with the treatment of marionette lines, smoothing chin dimples often requires both botulinum toxin and dermal fillers. A Word From Verywell Most people who receive Botox or other botulinum toxin injections are pretty happy with the results and go on to purchase more injections. However, treatment with such agents is a temporary measure with lines returning after about 120 days. Furthermore, as with all medical treatments, treatment with Botox carries its own risks of adverse effects (mostly short-lived) including swelling, muscle weakness, and pain. For instance, Nicole Kidman famously told La Republica, "I did try Botox, unfortunately, but I got out of it and now I can finally move my face again." If you're interested in Botox, please make an appointment with a specialist for an evaluation and to discuss your options. Was this page helpful? Thanks for your feedback! Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Email Address Sign Up There was an error. Please try again. Thank you, , for signing up. What are your concerns? Other Inaccurate Hard to Understand Submit Article Sources "Aesthetic Uses of the Botulinum Toxin" by A Dorizas and co-authors published in Dermatologic Clinics in 2014. Cochrane review titled "Botulinum toxin for facial wrinkles (Protocol)" by CP Camargo and co-authors published in 2014.