The Differences Between Fibromyalgia and Polymyalgia Rheumatica

How They're Different

An elderly woman clutches her painful shoulder.
Jose Luis Pelaez Inc/Getty Images

We hear all the time that it's hard to diagnose fibromyalgia because it's similar to so many other conditions. One of those similar conditions is polymyalgia rheumatica (PMR).

It's possible that PMR could be misdiagnosed as fibromyalgia (or vice versa), or that either condition could be overlooked in someone who's already diagnosed with the other.

These two conditions, however, are very different and require different treatments. Knowing the symptoms of both can help you recognize whether you may have a new or undiagnosed condition that needs to be addressed.

What is Polymyalgia Rheumatica?

PMR is an inflammatory disease that's believed to be autoimmune. It's seen almost exclusively in people over 65. Doctors may not even consider it in someone who's not a senior citizen.

Among people older than 50, about 0.5 percent have PMR, making it a rare disease. (To give you a comparison, fibromyalgia impacts between two and four percent of the U.S. population.) However, a 2014 study in Rheumatology International suggested that PMR may be present in about three percent of people with fibromyalgia. If that's true, it'd make it considerably more common in this group than in the general population.

PMR generally causes muscle pain and stiffness in specific parts of the body, including the:

  • Shoulders
  • Neck
  • Upper arms
  • Hips
  • Buttocks
  • Thighs
  • Sometimes the wrists, elbows, or knees

The stiffness is almost always worst in the morning, when it can severely limit the ability to perform even basic tasks such as getting out of bed and getting dressed.

PMR can include other symptoms as well, such as:

  • Fatigue
  • Low-grade fever
  • Loss of appetite
  • Malaise (a general feeling of unwellness)
  • Depression

When this disease strikes, symptoms generally come on quickly.

How PMR and Fibromyalgia Are Different

Let's look at the information above, point by point, to compare these two conditions.

  • PMR can include fatigue, low-grade fever, loss of appetite, malaise and depression. Fibromyalgia involves fatigue and may involve depression. Fever, loss of appetite, and malaise are not considered fibromyalgia symptoms. (Chronic fatigue syndrome is common in people with fibromyalgia, though, and it can include fever and malaise.)
  • PMR generally comes on quickly. Some cases of fibromyalgia come on quickly while others involve a slow build-up of symptoms.

A Word from Verywell

No single blood test can diagnose PMR. Doctors consider the full range of symptoms along with a lab test called the sedimentation (or "sed") rate. An elevated sed rate is an indicator of inflammation. (In people with fibromyalgia, the sed rate is typically normal or just slightly elevated.)

PMR is generally treated with steroids and can often be well controlled. Some people with fibromyalgia may not tolerate steroids, but this is not a universal problem. Make sure to discuss treatment options, and any side effects you experience, with your doctor to determine the best treatments for you.

It can also help to learn more about PMR and how it can impact your life.

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