Arthritis Treatment Pain Relief Using Ginger to Ease Arthritis Symptoms By Carol Eustice Carol Eustice Facebook Carol Eustice is a writer covering arthritis and chronic illness, who herself has been diagnosed with both rheumatoid arthritis and osteoarthritis. Learn about our editorial process Updated on December 21, 2020 Medically reviewed by Lana Butner, ND, LAc Medically reviewed by Lana Butner, ND, LAc Facebook LinkedIn Lana Butner, ND, LAc, is a board-certified naturopathic doctor and licensed acupuncturist in private practice in New York City. Learn about our Medical Expert Board Print Table of Contents View All Table of Contents For Osteoarthritis For Rheumatoid Arthritis Dosage and Preparations Side Effects Precautions and Warnings Ginger (Zingiber officinale) may help treat symptoms associated with osteoarthritis (OA) and rheumatoid arthritis (RA). Research shows that phytochemicals in ginger—including gingerol, shogoal, and zingerone—have anti-inflammatory properties that may help relieve arthritis joint pain and inflammation. In fact, lab studies show that these compounds inhibit several of the very same targets as arthritis medications. A tropical plant with green-purple flowers, ginger's aromatic root has been used for centuries in folk medicine to relieve pain and ease nausea. The spice is also commonly used in Asian and Caribbean cuisine. Verywell / Anastasiia Tretiak Benefits for Osteoarthritis (OA) Osteoarthritis is a painful joint condition caused by wear and tear of cartilage, the protective tissue around joints. While this degenerative damage can occur in any joint, it commonly affects joints in the hands, knees, hips, and spine. Anti-inflammatory phytochemicals in ginger can relieve pain and swelling associated with OA. A three-month clinical trial involving 120 people with knee osteoarthritis found ginger supplements help to decrease pro-inflammatory cytokines tumor necrosis factor (TNF) and interleukin-1-beta (IL-1b). Combining ginger with echinacea may boost its pain-relieving properties, according to a small study published in the journal Natural Products Research. The study gave 15 people with chronic OA knee pain, who did not respond to non-steroidal anti-inflammatory drugs (NSAIDs), the herbal combo for 30 days. At the end of the study, patients reported significant reductions in pain based on pain rating scales. Ginger may also be effective as a topical pain reliever. A 2017 study of 68 people with OA of the knee found that self-massaging the knee with ginger oil helped relieve pain better than plain massage oil. Diet, Exercise, and Managing OA Benefits for Rheumatoid Arthritis (RA) RA is an autoimmune disorder in which the body mistakenly attacks synovial tissue and fluid in the joints, resulting in inflammation and pain in affected joints. Compounds in ginger have been shown to play a potential therapeutic role in its treatment. In in vitro studies, ginger extract was found to reduced the inflammatory reactions in synovial cells as well as the corticosteroid Celestone (betamethasone). The research also indicates that ginger is potentially more effective at reducing inflammation than ibuprofen. Ginger appears to reduce RA-related inflammation by altering gene expression. Laboratory studies isolated a compound in ginger known as 1-dehydro-(10) gingerdione, which helps regulate inflammatory genes. A 2019 clinical trial found that ginger increases the expression of anti-inflammatory genes while decreasing pro-inflammatory gene expression in people with RA. Further research suggests ginger paired with turmeric may actually protect against damage caused by the autoimmune response in RA. In animal studies, the spice combo was found to have a protective effect not only on joints, but also on the heart, lungs, and kidneys—common extra-articular complications in rheumatoid diseases. Besides TNF and IL-1b, ginger can have a therapeutic effect on cyclooxygenase (COX) and nuclear factor kappa-light-chain-enhancer of activated B cells (NFkB)—additional inflammation mediators. 13 Natural Anti-inflammatory Supplements Verywell / Anastasia Tretiak Dosage and Preparations As a dietary supplement, ginger is available as a powder, extract, tincture, capsules, tea, and oils. The recommended dose is up to 2 grams in three divided doses per day, or up to four cups of ginger tea daily. If you would like to try applying ginger essential oil directly into affected joints, add two to three drops into a tablespoon of a carrier massage oil and rub it on the area twice a week. You can benefit from the medicinal properties of ginger by adding it to recipes as well. Some research even suggests it may work better in the whole-food form. However, it's harder to get a consistent therapeutic dose when you use ginger as an ingredient rather than taking it medicinally. Side Effects When used as a spice, ginger is generally regarded as safe. Most people do not experience side effects when ginger is taken in small doses. However, some people may experience: BloatingGasHeartburnNausea Precautions and Warnings Although there are no confirmed drug interactions with ginger, research suggests its mechanism of action may interact with blood thinners such as Coumadin (warfarin). It is advised to avoid ginger supplements while taking blood thinners. Do not use ginger supplements if you have gallstones. Before taking ginger supplements, talk to your healthcare provider to make sure it is right for you. Make sure you tell your practitioner about all of the prescription and over-the-counter medications and supplements you take. Turmeric May Be a Solution For Osteoarthritis Knee Pain, Study Finds 12 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Rahmani AH, Shabrmi FM, Aly SM. Active ingredients of ginger as potential candidates in the prevention and treatment of diseases via modulation of biological activities. Int J Physiol Pathophysiol Pharmacol. 2014;6(2):125-136. NIH: National Center for Complementary and Integrative Health. Ginger. Mayo Clinic. Osteoarthritis. Mozaffari-Khosravi H, Naderi Z, Dehghan A, Nadjarzadeh A, Fallah Huseini H. Effect of Ginger Supplementation on Proinflammatory Cytokines in Older Patients with Osteoarthritis: Outcomes of a Randomized Controlled Clinical Trial. J Nutr Gerontol Geriatr. 2016;35(3):209-218. doi:10.1080/21551197.2016.1206762 Rondanelli M, Riva A, Morazzoni P, et al. The effect and safety of highly standardized Ginger (Zingiber officinale) and Echinacea (Echinacea angustifolia) extract supplementation on inflammation and chronic pain in NSAIDs poor responders. A pilot study in subjects with knee arthrosis. Nat Prod Res. 2017;31(11):1309-1313. doi:10.1080/14786419.2016.1236097 Tosun B, Unal N, Yigit D, Can N, Aslan O, Tunay S. Effects of Self-Knee Massage With Ginger Oil in Patients With Osteoarthritis: An Experimental Study. Res Theory Nurs Pract. 2017;31(4):379-392. doi:10.1891/1541-6577.31.4.379 Ribel-Madsen S, Bartels EM, Stockmarr A, et al. A synoviocyte model for osteoarthritis and rheumatoid arthritis: response to Ibuprofen, betamethasone, and ginger extract-a cross-sectional in vitro study. Arthritis. 2012;2012:505842. doi:10.1155/2012/505842 Al-Nahain A, Jahan R, Rahmatullah M. Zingiber officinale: A Potential Plant against Rheumatoid Arthritis. Arthritis. 2014;2014:159089. doi:10.1155/2014/159089 Aryaeian N, Shahram F, Mahmoudi M, et al. The effect of ginger supplementation on some immunity and inflammation intermediate genes expression in patients with active Rheumatoid Arthritis. Gene. 2019;698:179-185. doi:10.1016/j.gene.2019.01.048 Ramadan G, El-Menshawy O. Protective effects of ginger-turmeric rhizomes mixture on joint inflammation, atherogenesis, kidney dysfunction and other complications in a rat model of human rheumatoid arthritis. Int J Rheum Dis. 2013;16(2):219-29. doi: 10.1111/1756-185X.12054 Arthritis Foundation. Supplement and herb guide for arthritis symptoms. Bode AM, Dong Z. The Amazing and Mighty Ginger. In: Benzie IFF, Wachtel-Galor S, eds. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd ed. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. By Carol Eustice Carol Eustice is a writer covering arthritis and chronic illness, who herself has been diagnosed with both rheumatoid arthritis and osteoarthritis. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit