Lumps and Bumps of the Hands and Wrists

Many things can cause the formation of lumps and bumps on the hands and wrists. In some cases, the masses may visible and physically aggravating. In others, they may not be felt or noticed at all. The causes of these growths are diverse, ranging from benign cysts to rare cancers of the bone, cartilage, and soft tissue.

Diagnosis can often be made with a physical examination of the mass as well as imaging studies, such as an X-ray or MRI when needed. A definitive diagnosis may require an evaluation of tissue samples by a pathologist, either obtained by a biopsy or surgical removal of the mass.

Common Hand or Wrist Masses

Common causes of lumps in the hand and wrist
Verywell / Alexandra Gordon

When diagnosing a hand or wrist mass, a doctor will typically explore the most common causes first, usually noncancerous growths, cysts, and tumors. The most common causes include the following conditions.

Ganglion Cysts

Ganglion cysts are considered the most likely suspect, representing about 50% of all abnormal hand and wrist growths. Ganglion cysts are caused when the lining of the small joints forms a small pouch into which fluids leach and accumulate. Cysts can also form pouches in the sheath covering a tendon or knuckle joint, which we refer to as a mucous cyst.

Giant Cell Tumor of the Tendon Sheath

Giant cell tumor of tendon sheath is not a true tumor but rather a mass that arises from the lining of a tendon (sheath) or a joint (synovium).

Giant cell tumors of the tendon sheath tend to grow slowly and can often become extremely painful. The problem with these masses is that they are easily removed but often come back.

Inclusion Cysts

Inclusion cysts are benign growths caused by an injury to a hand or finger, often developing years after the injury. Inclusion cysts are caused when a penetrating wound, such as a deep cut, pushes surface cells into the deep layers of the hand or finger. These cells, considered foreign, are encapsulated by the immune system and gradually expand in size over time.

Carpal Boss

Carpal boss is the overgrowth of bone on the back of the hand similar in appearance to a bone spur. It is essentially a small area of osteoarthritis occurring at the junction of the long hand bones and small wrist bones.

While frequently misdiagnosed as a ganglion cyst, a carpal boss is invariably firmer and fixed in its position. Unlike a cyst, you cannot move it or feel any "give" when you press on it. 


Enchondroma is a noncancerous tumor that develops when cartilage grows inside a bone. An enchondroma can become a problem if and when the tumor weakens the bone, increasing the risk of a pathologic fracture. Enchondromas are mostly benign with only around one percent developing into cancer.

Cancer of the Hands or Wrists

When cancer develops beneath the skin of the hand or wrist, it is most often due to a malignancy that has spread (metastasized) from a tumor in another part of the body, most often the lungs. The hand and wrist are not common locations for cancers to spread, but it is not impossible.

While cancer seldom originates in the hands or wrists, there are rare cases where tumors have formed in the bone or cartilage of the hand. These cancers are called sarcomas and represent less than 1% of all solid tumor malignancies in adults.

By contrast, one in five children with cancer will have a sarcoma. They predominantly develop in soft tissue (such as fat and muscle), although around 10 percent will occur in the bones of the hands or wrists.

It is not entirely clear what causes sarcoma. Family history and exposure to chemicals or radiation are known to play a part. In most situations, the cause is not clear.

These types of cancers are serious problems that often require invasive treatment and prolonged care. It is important to have this condition fully evaluated when there is a concern for a sarcoma.

A Word From Verywell

The vast majority of lumps and bumps on the hand and wrist are small symptoms of a minor condition. That said, there are situations that can be more worrisome. While most often these lumps and bumps can be managed with simple treatments, there are times when they are signs of a more serious problem.

It is worthwhile to have an unusual mass on the hand checked by your physician. As long as things look okay, some simple treatments are likely to help alleviate symptoms.

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  1. Nahra ME, Bucchieri JS. Ganglion cysts and other tumor related conditions of the hand and wrist. Hand Clin. 2004;20(3):249-60, v. doi:10.1016/j.hcl.2004.03.015

  2. Ozalp T, Yercan H, Kurt C, Ozdemir O, Coşkunol E. [Giant-cell tumors of the tendon sheath involving the hand or the wrist: an analysis of 141 patients]. Acta Orthop Traumatol Turc. 2004;38(2):120-4.

  3. Park MJ, Namdari S, Weiss AP. The carpal boss: review of diagnosis and treatment. J Hand Surg Am. 2008;33(3):446-9. doi:10.1016/j.jhsa.2007.11.029

  4. Plate AM, Lee SJ, Steiner G, Posner MA. Tumorlike lesions and benign tumors of the hand and wrist. J Am Acad Orthop Surg. 2003;11(2):129-41.

  5. Sur YJ, Kang YK, Bahk WJ, Chang DK, Rhee SK. Metastatic malignant tumour in the hand. J Plast Surg Hand Surg. 2011;45(2):90-5. doi:10.3109/2000656X.2011.556224

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