Can You Die From Lupus?

For many people who have been diagnosed with lupus, the first question that comes to mind may be: Can you die from lupus?

The short answer is, unfortunately, yes. However, most people living with lupus today can expect to live a normal lifespan.

There is no cure for lupus, so this is a question many newly diagnosed patients ask — or want to ask.

Lupus was once much more deadly. Only 50 percent of people diagnosed with lupus in 1955 were expected to live for more than four years.

Researchers say the survival rate for patients with systemic lupus erythematosus (SLE) has improved for many reasons. These include:

• Improvements in the classification of patients
• Earlier diagnosis
• Inclusion of milder cases
• More aggressive treatment such as the use of cytotoxic/immunosuppressive agents and pulse high-dose prednisone
• Advances in the treatment of hypertension, infections and renal failure, including renal dialysis and transplantation

Lupus is a chronic autoimmune disorder. In people who have lupus, the immune system attacks healthy cells and tissues, which causes pain, swelling and organ damage, among other symptoms.

Lupus can damage many parts of the body, including the:

• Joints
• Skin
• Kidneys
• Heart
• Lungs
• Blood vessels
• Brain

Kidney failure used to be the most common cause of lupus mortality. Today, when lupus is fatal, it's usually not because of active disease. Instead, death is usually caused by complications of the disease and treatment, such as infections, heart disease, and cancer.

Evidence suggests that active disease causes about a third of lupus deaths, while complications of the disease or its treatment (especially corticosteroids and immunosuppressants) cause about two-thirds of lupus deaths.

Lupus complications are increasingly related to aggressive treatments. These treatments can extend a patient's life considerably, but their side effects may eventually take a health toll.

The severity of your lupus factors into your life expectancy. It's been shown that people with more severe lupus tend to have shorter lifespans. This is probably because patients with severe disease have more disease complications and get more aggressive treatment.

The bottom line: Don't lose hope. You can live a full lifespan with a lupus diagnosis.