Cancer Treatment What Is Hydrogen Peroxide Therapy? Exploring the grey area of oxidative therapy for cancer By Angelica Bottaro Angelica Bottaro Facebook LinkedIn Angelica Bottaro is a writer with expertise in many facets of health including chronic disease, Lyme disease, nutrition as medicine, and supplementation. Learn about our editorial process Published on September 17, 2021 Medically reviewed by Douglas A. Nelson, MD Medically reviewed by Douglas A. Nelson, MD LinkedIn Douglas A. Nelson, MD, is double board-certified in medical oncology and hematology. He was a physician in the US Air Force and now practices at MD Anderson Cancer Center, where he is an associate professor. Learn about our Medical Expert Board Print Table of Contents View All Table of Contents What Is It and How Does It Work? Uses Risks Types of Hydrogen Peroxide Therapy Legality Frequently Asked Questions Hydrogen peroxide (H202) is a chemical compound commonly used for disinfecting surfaces, bleaching hair or whitening teeth, and cleaning small wounds. Some people believe that hydrogen peroxide can cure or treat cancer. Hydrogen peroxide is an oxidizing liquid, meaning it produces oxygen. It's believed that hydrogen peroxide can introduce oxygen into cancer cells and kill them. This type of treatment is known as oxidative therapy. In this article, we'll go into greater detail about how hydrogen peroxide therapy works and learn whether or not current evidence supports claims that it can treat or cure cancer. Natt Boonyatecha / Getty Images What Is Hydrogen Peroxide Therapy? Hydrogen peroxide therapy is given intravenously (IV), which means it's administered directly into the bloodstream. The two elements that make up the chemical are water and oxygen. When hydrogen peroxide is in the body, it breaks down into those two elements. Putting hydrogen peroxide into the body introduces more oxygen, which is believed to help with certain conditions. It’s thought that the oxygen molecules from the dissolving hydrogen peroxide can kill cancer cells because too much oxygen can be toxic to these cells. Should You Use Hydrogen Peroxide on Your Skin? What Has Hydrogen Peroxide Therapy Been Used For? Hydrogen peroxide was first discovered in 1818, however, it wasn’t until the late 1800s that it was used to treat scarlet fever, bacterial infections, and tonsillitis. Following the First World War, it was also used to treat influenza and pneumonia. In the 1960s, doctors conducted more studies on the effects of the chemical and found that it could be used to help promote oxidation. That’s when oxidative therapy, a group of therapies that stimulate the immune system by using oxygen, ozone gas, or hydrogen peroxide, was pioneered. Oxidative therapy was used to help treat cancer, skin diseases, and polio. Is There Any Evidence to Support Hydrogen Peroxide Therapy? There is no evidence supporting the claims that some doctors have made about the use of hydrogen peroxide therapy as a treatment for cancer. So far, any research that does demonstrate the health benefits of the chemical is limited and centers around other health conditions and diseases. Research and the Risks No evidence supports that hydrogen therapy can treat cancer, and many studies have suggested that it is not safe. One study found that hydrogen peroxide may actually aid in the development of cancer by creating a good environment for the disease to flourish. That's because the production of hydrogen peroxide in the body can lead to accelerating aging, inflammation, and DNA damage, all of which can lead to the development and spread of cancer cells. Another study found that people who had ingested hydrogen peroxide in high doses over the course of a 10-year period experienced adverse health effects, such as stroke, disability, and death. Can I Use Peroxide and Alcohol on My Incision? Types of Hydrogen Peroxide Therapy Hydrogen peroxide therapy is primarily administered intravenously (IV), which means it's administered directly into the bloodstream. Is Hydrogen Peroxide Therapy Legal? The use of IV and oral hydrogen peroxide has not been clinically tested nor approved by the U.S. Food and Drug Administration (FDA). The substance is not illegal. However, there are regulations that limit the concentration of hydrogen peroxide that can be used for medicinal and industrial purposes. For example, hydrogen peroxide that can be purchased over the counter typically contains 3% to 9% of the substance. Many of the IV and oral concentrations used at clinics and wellness centers are as high as 35%, which is a concentration typically only for external use or as an industrial cleaner or disinfectant. Ingesting hydrogen peroxide can erosion, ulcers, and perforation in your stomach. The U.S. Food and Drug Administration (FDA) conducts its own studies on medical products to convey the best and most accurate information to the public. This means that a product can be legal to buy, own, sell, or use and still not be approved by the FDA. In the case that a product is legal but not FDA-approved, it is used off-label. It can mean that the product is not designed to treat a certain condition, is not approved for the dosage or administration route, or is not approved for a certain age group. Summary Hydrogen peroxide is an oxidizing liquid that creates oxygen in the body. Some people believe it can help treat or cure cancer because high levels of oxygen may be toxic to cancer cells and can kill them. However, hydrogen peroxide is not FDA-approved for treating cancer. Also, studies have shown that hydrogen peroxide may actually promote cancer cell growth and spread. The substance is dangerous to use internally, and should only be used topically. A Word From Verywell The thought of hydrogen peroxide therapy being a cure for cancer may sound alluring. However, no research has shown that the substance can help with cancer. Some studies have even found that using it to treat cancer could have the opposite effect. Using hydrogen peroxide therapy can cause more harm than good. If you are still considering the use of hydrogen peroxide for cancer treatment, you should ask your doctor about the risks of hydrogen peroxide therapy and discuss safer treatment options. Frequently Asked Questions Does hydrogen peroxide therapy for cancer work? According to claims, hydrogen peroxide therapy works by introducing oxygen into cancer cells to essentially drive their death by raising oxygen levels in your body. However, there is no evidence that supports that it can treat cancer. In fact, many studies have found that hydrogen peroxide can actually do the opposite and drive the growth of cancer. Is it safe to do a hydrogen peroxide IV? IV hydrogen peroxide therapy has not been approved by the FDA. Clinical trials studying its use intravenously have also not been done. Reports and research surrounding its safety has found that serious adverse effects can occur. Since hydrogen peroxide is not approved, the substance should not be used intravenously for medical purposes. What are the other benefits of hydrogen peroxide therapy? Although hydrogen peroxide shouldn’t be ingested or injected into the bloodstream, it does have some benefits. For example, it can be used to help whiten teeth or clean minor scrapes if used at a low concentration. 8 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Cervantes Trejo A, Castañeda ID, Rodríguez AC, et al. Hydrogen peroxide as an adjuvant therapy for COVID-19: a case series of patients and caregivers in the Mexico City metropolitan area. Evid Based Complement Alternat Med. 2021;2021:e5592042. doi:10.1155/2021/5592042 Park WH. Hydrogen peroxide inhibits the growth of lung cancer cells via the induction of cell death and G1‑phase arrest. Oncol Rep. 2018;40(3):1787-1794. doi:10.3892/or.2018.6535 Armogida M, Nisticò R, Mercuri NB. Therapeutic potential of targeting hydrogen peroxide metabolism in the treatment of brain ischaemia. Br J Pharmacol. 2012;166(4):1211-1224. doi:10.1111/j.1476-5381.2012.01912.x Marcial-Vega V, Idxian Gonzalez-Terron G, Levy TE. Intravenous ascorbic acid and hydrogen peroxide in the management of patients with chikungunya. Bol Asoc Med P R. 2015 Jan-Mar;107(1):20-24. Lisanti MP, Martinez-Outschoorn UE, Lin Z, et al. Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer". Cell Cycle. 2011;10(15):2440-2449. doi:10.4161/cc.10.15.16870 Hatten BW, French LK, Horowitz BZ, Hendrickson RG. Outcomes after high-concentration peroxide ingestions. Ann Emerg Med. 2017;69(6):726-736.e2. doi:10.1016/j.annemergmed.2016.11.022 National Center for Biotechnology Information. PubChem compound summary for CID 784, hydrogen peroxide. U.S. Food and Drug Administration. Understanding the regulatory terminology of potential preventions and treatments of COVID-19. By Angelica Bottaro Angelica Bottaro is a professional freelance writer with over 5 years of experience. She has been educated in both psychology and journalism, and her dual education has given her the research and writing skills needed to deliver sound and engaging content in the health space. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit