Digestive Health Irritable Bowel Syndrome Related Conditions IBS and Interstitial Cystitis (Painful Bladder Syndrome) By Barbara Bolen, PhD Barbara Bolen, PhD Twitter Barbara Bolen, PhD, is a licensed clinical psychologist and health coach. She has written multiple books focused on living with irritable bowel syndrome. Learn about our editorial process Updated on July 26, 2022 Medically reviewed by Jenny Sweigard, MD Medically reviewed by Jenny Sweigard, MD LinkedIn Jenny Sweigard, MD, is a board-certified physician involved in patient care, including general medicine and critical care medicine. Learn about our Medical Expert Board Print Table of Contents View All Table of Contents What Is IC? Symptoms Treatment Options Dietary Interventions Overlap When You Have Both Interstitial cystitis (IC), also known as painful bladder syndrome, on the surface, looks like the urological counterpart of irritable bowel syndrome (IBS). If you have the misfortune of having both, you may be wondering if they are related. Let's take a look at what is known about interstitial cystitis and any possible overlap with IBS. hsyncoban / Getty Images What Is IC? Interstitial cystitis is a health condition in which a person experiences chronic pain and discomfort related to the bladder. IC can be experienced by men but is seen with significantly greater frequency in women. There are no known clear-cut causes of IC although, for some, IC may develop following a urinary tract infection, childbirth or hysterectomy. IC symptoms can wax and wane without any clear pattern. Similar to IBS, IC is diagnosed after other disorders have been ruled out. Symptoms The most common IC symptoms are: Recurrent bladder pain, pressure and/or discomfort Chronic pelvic pain Urinary urgency Increased frequency of urination Need to urinate through the night (nocturia) The intensity of IC pain and discomfort may change as the bladder fills and empties. For women, IC symptoms may be exacerbated during menstruation. For both men and women, IC may contribute to pain during sexual intercourse. Treatment Options As you can see, the treatment options for IC range widely: IC medication, oral or inserted into the bladder directly Other medications, including OTC analgesics, tricyclic antidepressants, antihistamines, and antispasmodics Bladder training Physical therapy Biofeedback TENS (transcutaneous electrical nerve stimulation) Surgery Dietary Interventions Some types of foods have also been associated with exacerbating IC symptoms. An elimination diet should be used to identify problematic foods so as to avoid unnecessary nutrient restriction. As you will see, many of these foods are also foods that may trigger IBS. Acidic foodsAlcoholic beveragesArtificial sweetenersCaffeineChocolateCitrus fruits and juiceCoffee and teaTomatoes and tomato sauceSpicy foods Overlap Between IC and IBS Research has shown that individuals who suffer from IC are more likely to suffer from other chronic disorders, including IBS. The reason for the overlap is unknown but does suggest a more system-wide dysfunction. Researchers are looking into the role of inflammatory processes, a "cross-sensitization" among the nerves of the bladder and the bowel, and other central nervous system dysfunction to better understand the underlying factors responsible for the initiation and maintenance of these chronic conditions. What to Do If You Have Both The establishment of a good working partnership with a healthcare provider would certainly be ideal if you are suffering from both IC and IBS. Your healthcare provider can help you to sort through the various treatment options for both conditions to sort out which options might benefit both, without exacerbating one or the other. Since certain foods have a reputation for aggravating either condition, keeping a symptom diary and using an elimination diet may help you to identify foods that are contributing to your bowel or bladder symptoms. As there may be some system-wide dysfunction that is contributing to both your IC and IBS problems, it might be helpful to look into holistic health approaches. Mind/body activities, such as yoga, meditation, and the regular use of relaxation exercises, can help to ease anxiety and stress, both of which can enhance pain sensations. 6 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. National Institute of Diabetes and Digestive and Kidney Diseases. Definition & Facts of Interstitial Cystitis. National Institute of Diabetes and Digestive and Kidney Diseases. Symptoms & Causes of Interstitial Cystitis. Parsons CL. How does interstitial cystitis begin? Transl Androl Urol. 2015;4(6):605–610. doi:10.3978/j.issn.2223-4683.2015.11.02 National Institute of Diabetes and Digestive and Kidney Diseases. Treatment for Interstitial Cystitis. National Institute of Diabetes and Digestive and Kidney Diseases. Eating, Diet, & Nutrition for Interstitial Cystitis. Ratner V. The Interstitial Cystitis Association of America: lessons learned over the past 30 years. Transl Androl Urol. 2015;4(5):491–498. doi:10.3978/j.issn.2223-4683.2015.09.02 By Barbara Bolen, PhD Barbara Bolen, PhD, is a licensed clinical psychologist and health coach. She has written multiple books focused on living with irritable bowel syndrome. 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