Sexual Health Birth Control Prescription Options Print Minimizing Birth Control Side Effects How to choose the right birth control pill By Dawn Stacey, PhD, LMHC Updated July 05, 2019 Medically reviewed by a board-certified physician PhotoAlto/Antoine Arraou/Getty Images More in Birth Control Prescription Options How to Choose Contraception Using the Pill Over-the-Counter Types of IUDs Hormonal Methods Permanent Methods Emergency Contraception Condoms When Birth Control Fails Talking About Birth Control View All With so many combination birth control pills available, how do you know which to use? Most are equally effective, so the best choice for you will likely come down to which is likely to produce no (or very few) side effects. The doctor who prescribes your contraceptive will be your ultimate guide, but it's always wise to be as informed as possible about any drug you take, so in this guide to making an informed decision about which birth control pill is best for you, you'll find a review of the differences between the types of pills, the potential side effects of each, and more. A Quick Explanation About Choosing a Birth Control Pill In general, combination hormonal contraceptives contain a synthetic estrogen (to stabilize the endometrium and reduce unwanted spotting) and a progestin (for its contraceptive effects). Knowing the differences between the progestins and about estrogenic effects, androgenic effects, and progestational selectivity can help you choose a pill with minimal side effects. To briefly explain how the combination of these activities may cause side effects, let's look at some specific combination of birth control pills. Oral contraceptives that tend to have high androgenic effects and low estrogen activity, for example, are more likely to cause unwanted hair growth and acne side effects. Additionally, a progestin with higher androgenic effects may tend to produce less breast tenderness, bloating and mood changes. It is important to remember, though, that the majority of women using a pill with this combinations do not end up developing acne; this side effect is more likely to occur in those women who have a tendency toward androgenicity. Birth control pills containing this high androgenic/low estrogenic pattern include: AlesseEstrostep FELevlenLoestrin 1.5/30Loestrin 1/20 FeOvral Since there are different types of progestins, they each have different potency in terms of progestational, estrogenic, and androgenic effects. The result of these effects is dependent on the combination of the type and levels of progestin and estrogen. Typically, the balance (or ratio) between the estrogen and progestin in a pill brand may play a role in the side effects you are experiencing. Each woman may respond differently to these components. Also, the type of pill you may be using (monophasic/biphasic/triphasic or extended cycle) may help alleviate certain side effects. Because of that, please note that the following are general guidelines, and may not apply to all women. To be a little more technical, in order to determine the total combination of these three effects, a person needs to multiply the actual dose of these three components (effects) times the relative potency of that component in order to classify a birth control pill brand as having high androgenic effects, being estrogen dominant, or progestin dominant. Given the complexity of figuring this out on your own, the decision as to which birth control pill to use should be discussed with your healthcare provider. You can use this information to begin a conversation with your doctor about which pill type may be best for you. Give the pills you are currently taking a fair trial of at least two to three months. If you have switched your pill brand, you should also give the new ones a two- to three-month trial. It often takes a few months just for your body to adjust to the new hormones in your birth control pill. Choosing a Birth Control Pill by Minimizing Its Side Effects The following chart is a relative classification, so it may not apply to every female. When choosing a combination birth control pill, you may be able to minimize side effects by switching to (or initially picking) a pill brand suggested in the below chart based on which side effect you are trying to lessen or alleviate. Side Effect (Problem) Progestin/Estrogen/Androgenic Effects Try Using These Pill Brands to Minimize the Side Effect Acne higher estrogen, lower androgen potency Demulen 1/50, Brevicon, Mircette, Modicon, Necon, Ortho-Cyclen, Ortho-TriCyclen, Yasmin Breakthrough bleeding (spotting) higher estrogen, higher progestin potency, lower androgen potency Demulen 1/50, Desogen, Ortho-Cept, Ovcon 50, Yasmin, Zovia 1/50E, Estrostep FE** Breast soreness lower estrogen, lower progestin potency Alesse, Levlite Depression lower progestin potency Alesse, Brevicon, Levlite, Modicon, Necon 1/35, Ortho-Cyclen, Ortho-TriCyclen, Ovcon 35,Tri-Levlen, Triphasil, Trivora Endometriosis or endometriosis prevention lower estrogen, higher progestin potency, higher androgen potency Demulen 1/35, Levlen, Levora, Loestrin 1.5/30, Loestrin 1/20 Fe, LoOvral, Nordette, Zovia 1/35E (used either continuously with no days of placebo pills or with only 4 days of placebo pills for prevention) Headaches (not menstrual migraines) lower estrogen, lower progestin potency Alesse, Brevicon, Levlite, Modicon, Necon 1/35, Ortho-Cyclen, Ortho-TriCyclen, Ovcon 35, Tri-Levlen, Triphasil, Trivora Moodiness or irritability lower progestin potency Alesse, Levlite, Loestrin 1/20 Fe, Yasmin, Yaz, Beyaz (or any pill with less estrogen than currently on) Severe menstrual cramps higher progestin potency Demulen 1/35, Demulen 1/50, Desogen, Mircette, Loestrin 1.5/30, Ortho-Cept, Yasmin, Zovia 1/35E, Zovia 1/50E Weight gain lower estrogen, lower progestin potency Alesse, Levlite, Loestrin 1/20 Fe, Yasmin, Yaz, Beyaz (or any pill with less estrogen than currently on) Estrostep FE contains the progestin norethindrone acetate (this progestin typically has a higher androgen potency). Therefore, although Estrostep FE follows more of a high androgenic/low estrogenic pattern, this brand is a triphasic pill that was actually designed to help prevent breakthrough bleeding while attempting to keep hormone exposure as low as possible. Estrostep FE is a good example as to why the information in this chart should be viewed more in terms of being general guidelines, and may not always hold from one woman to another. A Word From Verywell Remember, every woman could react differently to specific birth control methods, so this information is meant to be a general overview. Also, it is important to point out that the main reason to use hormonal birth control is for contraception (to prevent an unintended pregnancy). Considering potential non-contraceptive benefits of birth control, as well as unwanted side effects, can be part of the discussion you have with your doctor when determining which hormonal method may be best suited for you. Was this page helpful? Thanks for your feedback! Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Email Address Sign Up There was an error. Please try again. Thank you, , for signing up. What are your concerns? Other Inaccurate Hard to Understand Submit Article Sources Jelovsek, R. Which Oral Contraceptive Pill Is Best for Me? Continue Reading What Are Combination Birth Control Pills and How Are They Used? Understanding What the Role of Progestin in Birth Control Is How Do You Choose Between Multiphasic vs. Monophasic Birth Control? Everything You Need to Know About Birth Control Pills The 8 Kinds of Progestin in Your Birth Control Using Hormonal Contraception for Reducing Androgens in Hirsutism 8 Hormonal Birth Control Options Get Info on How a Woman Can Switch to a New Birth Control Pill Ortho Tri-Cyclen Lo Is a Triphasic Birth Control Pill Missed a Birth Control PIll? Here's What to Do Learn the Benefits, Risks, and Side Effects of the Birth Control Pill What Is Lo Loestrin Fe and How Is It Different from Other Pills? Birth Control Pills and High Blood Pressure The Scoop on Continuous Cycle Birth Control Pills Learn If You Should Be Taking Ethinyl Estradiol (Synthetic Estrogen) Are Progestin-Only Birth Control Pills for You?