Treating Arthritis With Mobic (Meloxicam)

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Mobic (meloxicam) is one of the nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat certain types of arthritis. Mobic was approved by the U.S. Food and Drug Administration on April 14, 2000. The drug is manufactured by Boehringer Ingelheim Pharmaceuticals.


Mobic is not available as an over-the-counter drug. It is only available with a prescription.

Mobic comes in two strengths—7.5 mg (taken once or twice daily) and 15 mg (taken once daily) tablets. Mobic also is available in a 7.5mg/5mL oral suspension.


Mobic is prescribed to relieve signs and symptoms of osteoarthritis and rheumatoid arthritis. It is primarily used to reduce inflammation, stiffness, and pain.

Special Instructions

Many doctors instruct patients to take Mobic with food. Some resources say that Mobic can be taken with or without food. Other resources suggest taking it with a full glass of water. To prevent stomach upset, you can take it with food or milk. If stomach upset occurs, you can also take an antacid.

Patients Who Should Not Take Mobic

Patients who had episodes of asthma, hives, or allergic-like reactions after taking aspirin or any other NSAID should not take Mobic. Be sure your doctor knows about your previous drug reaction. Also, patients who have had ulcers, stomach bleeding, severe kidney problems, or severe liver problems are not candidates for treatment with Mobic.

Common Side Effects Can Occur Wit

Diarrhea, indigestion, nausea, headaches, dizziness, rash, and flu-like symptoms may occur for some patients taking Mobic.

What Special Warnings and Precautions Are Associated With Mobic?

Problems with stomach ulcers and stomach bleeding can occur with any NSAID, and Mobic is no exception.

Typically, these problems are tied to the long-term use of the drug but not always—the short-term use of Mobic or other NSAIDs can be problematic for some patients. Stomach ulcers and bleeding can occur without warning. Some people do get signs and warnings by experiencing burning stomach pain, black stools, or vomiting. Call your doctor if you are experiencing these symptoms.

Liver damage can occur in people taking NSAIDs like Mobic. Warning signs include nausea, vomiting, fatigue, appetite loss, itching, yellowing of the skin or eyes, and dark urine.

Mobic can cause fluid retention and swelling in the body. NSAIDs like Mobic have also been linked to increased blood pressure.

NSAIDs, including Mobic, are associated with an increased risk of adverse cardiovascular events, including heart attack, stroke, and new onset or worsening of pre-existing hypertension (high blood pressure). The cardiovascular risk may be increased with duration of use of Mobic or other NSAIDs or pre-existing cardiovascular risk factors or disease.

Drug Interactions

Certain drugs taken with Mobic can cause interactions which may alter the effectiveness of Mobic. Drugs which can cause interactions include:

Pregnant or Nursing Women

Women who are pregnant are advised not to take Mobic, especially in late pregnancy. Women who are nursing should also not take Mobic.

Signs of Overdose

As with any medication, there can be severe consequences of taking excessive doses of Mobic. An overdose of Mobic can cause drowsiness, nausea, vomiting, and stomach pain or bleeding. A large overdose has more severe consequences -- breathing problems, coma, convulsions, and heart attack. Be sure to take Mobic only as directed.


Meloxicam (marketed as Mobic). Consumer Information Sheet. U.S. Food and Drug Administration.

Mobic. PDRHealth.