Types of Arthritis and Rheumatic Diseases

In This Article

Patient describing wrist pain to physical therapist
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There are many different types of arthritis and rheumatic diseases. Because of the effect on the joints, tendons, ligaments, bones, and muscles, these conditions are also referred to as musculoskeletal diseases. If we want to be literal, using strict accuracy, arthritis is one aspect of the rheumatic diseases which affect the musculoskeletal system.

What Is Arthritis?

Arthritis literally means "joint inflammation." While "arthritis" technically describes a specific symptom associated with rheumatic diseases, the terms "arthritis" and "rheumatic disease" are often used interchangeably. In common speech, you may consider the terms synonymous.

What Are Rheumatic Diseases?

Rheumatic diseases are a group of diseases and conditions that are characterized by inflammation (typically with redness, heat, and swelling) and impaired function of one or more connecting or supporting structures of the body. Primarily, rheumatic diseases affect the joints, tendons, ligaments, bones, and muscles. Pain, stiffness, and swelling are common symptoms associated with rheumatic diseases, but there can also be systemic effects with certain conditions (i.e., may affect internal organs).

Who Is Affected?

It is estimated that 52.5 million people in the U.S. have arthritis or one of the rheumatic diseases, according to the Centers for Disease Control and Prevention (CDC).

There are over 100 rheumatic diseases and conditions. In the U.S., the most common types of arthritis or rheumatic diseases are osteoarthritis, gout, fibromyalgia, and rheumatoid arthritis—in that order according to prevalence.

Rheumatic diseases affect people of all races and age groups, including about 300,000 children. Certain types of arthritis or rheumatic diseases are more common among certain groups of people. Rheumatoid arthritis, fibromyalgia, scleroderma, and lupus are more common among women than men. Gout and spondyloarthropathies are more common among men than women. After menopause, the incidence of gout in women goes up. Lupus is both more common and more severe in African Americans and Hispanics compared to Caucasians.

Common Types of Arthritis and Rheumatic Diseases

Although you may be most familiar with the common osteoarthritis, there are actually many different types of arthritis and rheumatic diseases that can affect the body.

Ankylosing Spondylitis

Ankylosing spondylitis is a type of arthritis primarily characterized by chronic inflammation of the joints and ligaments of the spine. Pain and stiffness start in the spine and can progress to the neck and hips as the disease progresses. Over time, the bones in the spine can fuse causing loss of mobility and, in advanced cases, spinal deformity.

The exact cause of ankylosing spondylitis is unknown, but it's believed to have a genetic component. The disease primarily affects men, with the onset between the ages of 17 and 35. It can occur in anyone, though, at any age.

Ankylosing spondylitis is a progressive disease. Treatment can help manage pain and slow the progression.


Bursitis is a condition caused by inflammation of a bursa. Bursae are small fluid-filled sacs that act as cushions to reduce friction between bone and other moving parts, such as muscle, tendons, or skin.

Symptoms of bursitis include pain, stiffness, and swelling and warmth around the affected joint. Pain is often worse during and after activity. Most commonly bursitis affects the shoulders, elbows, knees, and hips.

The most common cause of bursitis is repetitive overuse of the joint in question. Other causes are prolonged pressure to the bursa or injury.

Most cases of bursitis resolve within a few months, with minimal treatment. Over-the-counter pain relievers, ice, and rest can help relieve pain while bursitis heals. Do see your doctor, though, to get an appropriate diagnosis and guidance for treatment.

Enteropathic Arthritis

Enteropathic arthritis is an inflammatory condition linked to inflammatory bowel diseases, Crohn's disease and ulcerative colitis.

Enteropathic arthritis symptoms and severity varies from person to person. It can cause pain and stiffness in the joints, especially the knees, hips, ankles, and lower back. It may also cause body aches.

With enteropathic arthritis, you'll get flares that come and go. It is a chronic condition, though.

Some of the treatments often used to treat arthritis can make inflammatory bowel diseases worse, so enteropathic arthritis must be treated with care. TNF inhibitors have successfully been used to treat this disease.


Fibromyalgia is an arthritis-related syndrome primarily characterized by widespread or generalized muscular pain, tender points, fatigue, digestive problems, sleep disturbances, and other assorted symptoms.

It's not a well-understood syndrome, and the cause of fibromyalgia is unclear. Women are much more likely than men to develop it.

There are no tests for fibromyalgia, so it's diagnosed primarily by ruling out other diseases. This can be a long, frustrating process not helped by the fact that friends and family may not fully understand what you're experiencing and believe it's "all in your head."

There is no one specific treatment for fibromyalgia. Instead, treatment can be broad and may include pain relievers (over-the-counter or prescription), lifestyle changes and self-care, anti-depressants, physical therapy, and other supportive treatments.


Gout is characterized by the sudden onset of intense pain, tenderness, warmth, redness, and swelling due to inflammation of an affected joint. It most commonly affects the big toe, but can also affect other joints in the foot, the elbows, wrists, and fingers.

Excess uric acid in the body and deposition of uric acid crystals in the affected joint and tissues cause the symptoms. With gout, you'll have acute flares that last several days followed by periods with no symptoms. Without treatment, flares get progressively worse.

Men are more likely to develop gout, as are those with kidney problems, or who are obese. Certain medications, like diuretics, also raise your risk of the disease.

Gout is diagnosed by lab testing coupled with a physical exam. Imaging tests can also be used to check for joint damage.

Reducing uric acid in the blood is key to managing gout. This is accomplished through diet and/or uric acid-reducing medications. Pain relievers, rest, and ice can help relieve pain during gout attacks.

Juvenile Idiopathic Arthritis

Juvenile idiopathic arthritis (JIA) is a type of arthritis that affects children 16 years old and under. There are seven recognized subtypes of juvenile idiopathic arthritis.

Signs of juvenile idiopathic arthritis include "typical" arthritis symptoms of joint pain, stiffness, and swelling. But some forms of JIA also cause fever, skin rash, swollen lymph nodes or spleen, eye inflammation, weight loss, and anemia.

Unfortunately, there isn't a simple test that can be used to diagnose JIA. Diagnosis can be made more difficult because young children can have trouble verbalizing exactly what they're feeling, and aches and pains can be caused by many other issues. Doctors diagnose JIA by reviewing your child's medical history and symptoms, along with results from various lab tests.

Observing your child can help with diagnosis, especially with young children who don't have the verbal skills to accurately convey what they're feeling. Do they have trouble running or walking up stairs? Do they seem stiff or reluctant to move first thing in the morning? How long have you noticed these issues? This is all information to relay to the doctor.

Juvenile idiopathic arthritis is managed through pain-relieving drugs, anti-inflammatory and/or anti-rheumatic medications, and often physical therapy.


Osteoarthritis is a degenerative joint disease that is considered the most common type of arthritis. It is caused by the breakdown of cartilage in one or more joints.

Also called "wear-and-tear" arthritis, osteoarthritis causes pain, stiffness and limited range of motion, joint inflammation, creaking or grinding of the joints, and joint instability.

People of any age can develop it but it's most common after age 65. Repetitive joint motion, prior injury to the affected joint, and being overweight also puts you at risk for developing osteoarthritis.

Osteoarthritis is a progressive disease, but early diagnosis and treatment help slow joint damage and relieve pain. In addition to pain-relieving drugs and anti-inflammatories, lifestyle considerations like gentle exercise and weight loss are extremely helpful.


You may not think of osteoporosis as an arthritic disease, but it is. Osteoporosis is a disease characterized by progressive bone thinning (i.e., decreased bone density) and consequently a high fracture risk. It's called a "silent disease" because it shows little to no symptoms until a fracture occurs.

Osteoporosis is more common in women than men, especially those with a small build and those of Caucasian or Asian descent. It can occur at any age but most often develops after age 50.

You can reduce your risk of developing osteoporosis by helping your body build strong bones. Adequate calcium and vitamin D intake, and regular weight-bearing exercise are crucial to build and maintain bone health.

Once osteoporosis has developed, it can't be cured. There are treatments that can help prevent further bone loss, however.

Polymyalgia Rheumatica

Polymyalgia rheumatica is a rheumatic condition characterized by musculoskeletal pain and stiffness in the neck, shoulders, and hips, lasting at least four weeks. Polymyalgia rheumatica may also cause flu-like symptoms like fever, fatigue, and weight loss.

There is no test for polymyalgia rheumatica, so diagnosis is made by reviewing symptoms and ruling out other diseases. It's most common in women over 50.

Polymyalgia rheumatica is treated with low-dose corticosteroids. Symptoms typically improve quickly, within a few days of beginning treatment. Most are able to stop treatment after several months to 2 years.


Pseudogout is a condition that develops when calcium pyrophosphate crystals accumulate in a joint and the tissues that surround the affected joint. It's often mistaken for gout, because the symptoms are nearly identical: sudden pain, swelling, and stiffness of the joints. The difference is pseudogout most often affects the knee instead of the big toe as with gout.

Pseudogout affects both men and women about equally. Your risk of developing pseudogout increases with age. Pseudogout can be diagnosed by drawing joint fluid and looking for calcium pyrophosphate crystals.

Although it can't be cured, pseudogout can be controlled with NSAIDs and low-dose colchicine.

Psoriatic Arthritis

Psoriatic arthritis is a rheumatic disease associated with psoriasis and chronic joint symptoms, which can develop separately. In most cases, psoriasis develops first with arthritis developing over time.

Psoriatic arthritis is an autoimmune disease, so it occurs when the body's immune system turns on itself. This causes inflammation, pain, stiffness, and skin lesions.

Treating psoriatic arthritis typically involves NSAIDs, anti-rheumatic drugs, and biologic drugs such as TNF blockers. Psoriatic arthritis can't be cured but can be controlled.

Rheumatoid Arthritis

Rheumatoid arthritis is a chronic, autoimmune, inflammatory type of arthritis with joint complications and potential systemic effects. Fever, weight loss, fatigue, and lost-lasting morning stiffness are symptoms of rheumatoid arthritis, in addition to joint pain and swelling.

While the exact cause isn't known, rheumatoid arthritis seems to be hereditary. You have up to five-fold greater risk of developing the disease if there is a history of it in your family.

Diagnosis is made through a combination of physical exams, lab, and imaging tests.

Rheumatoid arthritis is a progressive disease that isn't curable but is manageable. There are many treatment options available today to help control the disease including corticosteroids, NSAIDs, and biologic response modifiers.

Sjogren's Syndrome

Sjogren's syndrome is an autoimmune, inflammatory disease which can occur as a primary or secondary condition, primarily characterized by dry mouth and dry eyes. Other symptoms can include difficulty chewing and swallowing, sore throat and tongue, digestive problems, enlarged lymph nodes, and swollen joints.

The vast majority of people with Sjogren's syndrome are female. Genetic factors, as well as viral infections, and hormonal factors may play a role in development.

Treatment for Sjogren's is different for everyone. Depending on your symptoms, there are treatment options to help relieve dry mouth, dry eyes, and painful joints.


Lupus is an autoimmune, inflammatory disease which can affect the joints, skin, kidneys, lungs, heart, nervous system, and other organs of the body. Symptoms vary widely between individuals, but can include muscle and joint pain, fatigue, and fever. There are several types of lupus.

The exact cause is unclear, but environmental factors, genetic, and reaction to certain drugs may play a role. Because of the wide range of symptoms, and the fact that there is not a specific test for lupus, diagnosis is difficult.

Lupus can't be cured but can often be managed. Treatment varies depending on your symptoms and the severity of them. You and your doctor must work closely to develop the right treatment plant for you.


Tendonitis is a condition caused by inflammation of one or more tendons in the body. Symptoms are pain and tenderness of the joint, stiffness, cracking of the joint, or a lump on the tendon.

Tendonitis is most often caused by repetitive overuse of the tendon. It can also be caused by an injury, or due to other inflammatory disorders like rheumatoid arthritis.

Rest and restricted movement of the affected joint is the best treatment for tendonitis. In some cases, physical therapy may also be needed. Corticosteroids may be prescribed for chronic tendonitis.

Rare Types of Arthritis and Rheumatic Diseases

There are a few, rarer types of arthritis and rheumatic diseases that can develop.

Mixed Connective Tissue Disease

Mixed connective tissue disease (MCTD) is an autoimmune disease with overlapping characteristics of three connective tissue diseases: systemic lupus erythematosus, scleroderma, and polymyositis. In addition to joint pain, symptoms include muscle pain or weakness, low-grade fever, fatigue, and Raynaud's syndrome.

The cause of MCTD isn't known, but there may be a genetic. It's much more prevalent in women than in men, especially young women.

This disease is very difficult to diagnose because its symptoms overlap with other diseases, and the symptoms don't occur all at the same time. The distinguishing point with MCTD is the high concentrations of anti-U1 RNP (ribonucleoprotein) in the blood.

Treatment involves managing symptoms with anti-inflammatory medications, pain relievers, and other drugs as needed. Treatment is dependant on the severity of the symptoms, as some people are more affected and others less.


Polymyositis is characterized by inflammation and degeneration of the muscles. It typically begins with muscle groups closest to the trunk, but can affect other muscles over time. Muscles progressively get weaker to the point of affecting daily life.

Polymyositis develops gradually. It's most common in women between the ages of 40 and 60, but anyone may develop it at any age. It often occurs alongside other rheumatic diseases, and certain cancers. While there's no known cause, there does seem to be a genetic component.

High-dose corticosteroids and/or immunosuppressants are considered first-line treatments. With early and aggressive treatment, it's possible to achieve remission.

Reactive Arthritis

Reactive arthritis is a type of arthritis that occurs as a reaction to an infection somewhere in the body. Besides joint pain and stiffness, reactive arthritis also causes eye inflammation and inflammation of the urinary tract.

Reactive arthritis is often triggered by an infection in the bladder or urethra (or the vagina for women). It can also be triggered by an infection in the digestive tract caused by bacteria-contaminated food.

Most people fully recover from reactive arthritis within a year of developing it. Treatment can help manage symptoms until that time.

Septic Arthritis (Infectious Arthritis)

Septic arthritis, also called infectious arthritis, is an infection that develops in a joint. It is caused by a germ that travels through the body to a joint. The germ can be a bacterium, virus, or fungus. It can enter the body from any type of open wound.

Typically only one joint is affected, but it can affect several joints at once.

The symptoms of septic arthritis include pain (often severe), stiffness, and swelling of the affected joint. The pain comes on quickly. It may also cause fever, chills, fatigue or weakness, and nausea.

Septic arthritis is a medical emergency. If you, or your loved one, have symptoms of septic arthritis, see a doctor immediately.

Septic arthritis can cause severe damage to the joint in question. It can also lead to septic shock, which can be fatal if left untreated.

Anyone can develop septic arthritis, but it's most common in the very young and the elderly, and those with a compromised immune system. Diagnosis of septic arthritis is made through blood tests and synovial fluid analysis, to check for signs of infection.

Treatment of septic arthritis can involve antibiotics, surgical irrigation or debridement. Prompt treatment can reduce the amount of long-term damage caused to the joint.


Scleroderma is an autoimmune disease characterized by the abnormal growth of connective tissue which supports the skin and internal organs. There are two main types of scleroderma: localized scleroderma and systemic scleroderma.

Localized scleroderma causes affected areas of the skin to become hard and tight. Systemic scleroderma affects the skin, as well as organs and blood vessels.

There is no cure for scleroderma, but treatment can help control symptoms.


Vasculitis is a condition associated with inflammation of the blood vessels. It develops when your immune system mistakenly attacks the blood vessels, causing inflammation which restricts normal blood flow. Symptoms include pain, fever, loss of appetite, and various other signs depending on what areas of the body are affected.

Immunosuppressants and anti-inflammatories are often prescribed to treat vasculitis. Early treatment is key to help limit tissue and organ damage, and control symptoms.

A Word From Verywell

The aforementioned types of arthritis and rheumatic diseases are the most well-known, but the list is not exhaustive. There are more and some are quite rare. An early, accurate diagnosis is imperative to managing rheumatic diseases. Treatment options for rheumatic diseases depend on which specific disease or condition you have.

A rheumatologist is a specialist in the diagnosis and treatment of arthritis and rheumatic diseases. Your diagnosis is based on your medical history, a physical examination, laboratory tests, imaging studies, and in some rare cases, a tissue biopsy. If you suspect you have arthritis or a rheumatic disease based on early symptoms, consult your doctor.

Diagnosis can be complicated—some rheumatic diseases may have overlapping symptoms and may mimic another rheumatic disease. You need a rheumatologist to distinguish between the different conditions and set you on the right treatment path. Verywell is happy to provide you with the information you need as you move from symptoms to diagnosis to treatment to successful disease management.

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