How Lung Cancer Pain Is Treated

Causes of Cancer Pain and Methods for Managment

Pain is very common with lung cancer and can be quite profound, but you can get relief. Your pain management should be tailored to the exact source of your discomfort and may include a combination of medication and procedures. Getting control of your pain will improve your ability to cope as you go through cancer treatment so you can have a better quality of life during your recovery. The first step: Being upfront with your medical team about how you are feeling.

Home Remedies and Lifestyle

Lung cancer-associated pain may require medical intervention, but there are also some things you can do on your own to reduce your pain. These approaches may help minimize the amount of medication you need to use and decrease the overall burden of your pain.

Strategies you can incorporate into your life include:

  • Getting enough rest: Being tired can increase your perception of pain and reduce your pain tolerance. Make sure you are well rested to feel your best.
  • Dressing comfortably: Ill-fitting clothes or shoes or scratchy materials can add to unpleasant sensations due to complications like neuropathy due to chemotherapy.
  • Paying attention to your furniture: With lung cancer, chest aches or bone pain can hurt tremendously. Make sure your seating and your bed aren't placing extra pain-inducing pressure or adding to your discomfort in any way.
  • Using an ice pack: If you have soreness due to edema (fluid accumulation), an ice pack can help bring down the swelling.

These strategies can be helpful, but know that it's highly unlikely that simple at-home approaches will be enough to ease your discomfort on their own.

Over-the-Counter (OTC) Therapies

Often, pain due to lung cancer can be alleviated with OTC therapies. However, you should talk to your doctor before taking any medications because even non-prescription options can cause side effects that may be dangerous if you have lung cancer.

OTC pain medications your doctor might recommend for you include:

  • Non-steroidal anti-inflammatories (NSAIDs): Commonly used NSAIDs include Aleve (naproxen) and Advil (ibuprofen). These medications can relieve pain and fevers, typically without severe side effects. They have also been associated with better long-term lung cancer survival. However, NSAIDs can cause stomach upset and increase your risk of bleeding, especially if you are already predisposed to it.
  • Tylenol (acetaminophen): This mild pain reliever can offer relief, but it's not safe if you have liver disease—including liver metastasis from lung cancer.
  • Aspirin: Aspirin is a popular pain reliever that's also a blood thinner. Your doctor might recommend it if you also need to be taking a blood thinner for stroke prevention, but it can cause bleeding if you're at risk of this side effect.
  • Transdermal patches, such as Salonpas: These deliver analgesics directly through the skin. They are generally safe but can cause skin irritation and, in some cases, systemic side effects.
  • Capsaicin cream: This cream can be placed on the skin to help relieve pain. It might not have an effect on deep pain, but you might experience relief of some types of neuropathic pain.

Some OTC medications are also available in prescription-strength formulations. You and your doctor might decide that's the route for you if you experience only partial relief from these medications without substantial side effects.


When it comes to prescription medications, some types of pain tend to respond better to certain treatments. Your pain management will be tailored to the cause of your pain. There are a number of options.

Pain Killers

Pain due to metastasis or incisional pain after surgery may improve with strong opioid pain killers. Vicodin and Percocet are examples of such medications.

Opioid medications can cause severe drowsiness, which may interfere with your quality of life. They are also potentially addictive, so they're meant to be used as a treatment for severe pain only when a short duration of use is anticipated.

Neuropathic pain can feel like constant or intermittent burning or tingling. And chronic post-surgical pain can persist long after an incision has healed. These types of pain might not improve with OTC pain medications or opioids. Rather, chronic pain associated with lung cancer is often treated with tricyclic anti-depressants like Pamelor (nortriptyline), anti-seizure medications like Neurontin (gabapentin), or steroids like dexamethasone.

Additionally, some aspects of lung cancer discomfort, such as muscle stiffness or nausea, may improve with medical marijuana.

Management of Complications

Chest pain due to a chronic cough or breathing difficulties associated with lung cancer might require an approach that involves treatment of the pulmonary problems, such as with bronchodilators.

Severe edema can cause pain in areas that are swollen, and the swelling is treated with oral or intravenous (IV) corticosteroid treatment.

Mouth sores, which can develop due to chemotherapy, are managed with a diet that includes soft foods that aren't too acidic or spicy. Your dentist may also prescribe an ointment to help soothe sores.

Typically, OTC or prescription pain therapy won't completely eliminate pain due to pulmonary issues, edema, or mouth sores, but may be used along with treatments for disease management.

Surgeries and Specialist-Driven Procedures

Interventional pain control techniques include procedures that are directed to the anatomical location of the pain. They generally don't have systemic side effects, but they also only treat pain that's specifically targeted by the procedure (rather than diffuse pain throughout the body).

Some of these methods include:

  • Nerve block: With this procedure, pain medication is injected around a nerve or into the spine fluid (intrathecal delivery) to reduce the pain sensation mediated by the nerve. This is a temporary effect that may wear off after a few months.
  • Spinal cord stimulation: This procedure involves the implantation of a device that produces vibrations to reduce the sensation of pain. The device can be controlled with an external stimulator, and it can be removed in another procedure if necessary.
  • Neurosurgery: Removal of metastatic tissue can alleviate pain caused by spinal metastases. And when pain is persistent and severe, transecting the nerve that mediates pain signals can alleviate the sensation. This can result in permanent loss of sensation, however.
  • Radiation: This treatment can reduce the size of a tumor that's in the lungs or the size of metastatic lesions, which can substantially reduce pain in some circumstances.

Complementary and Alternative Medicine (CAM)

Counseling, biofeedback, physical therapy, and interventions like acupuncture and massage may help you relax and reduce lung cancer-associated pain that's accentuated by stress or anxiety.

These are not substitutes for medical or interventional pain treatments, but they might help reduce your need for such therapies.

Consider talking with your medical team or a support group to get information about CAM therapies and to hear what others have to say about it.

A Word From Verywell

Pain can have a major effect on your quality of life. As you are managing your lung cancer treatment and recovery, don't hesitate to express your feelings about your pain to your medical team. If you have concerns about medication side effects or the potential for addiction, discuss these issues with your doctor so you can use a treatment approach that you feel comfortable with. It's also important that you give your doctors feedback about your treatment so it can be adjusted, if necessary.

Was this page helpful?
Article Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. Whisenant MS, Williams LA, Garcia Gonzalez A, et al. What do patients with non-small-cell lung cancer experience? Content domain for the MD Anderson Symptom Inventory for Lung Cancer [published online ahead of print, 2020 Jun 15]JCO Oncol Pract. 2020;JOP1900577. doi:10.1200/JOP.19.00577

  2. Rossi E, Noberasco C, Picchi M, et al. Complementary and integrative medicine to reduce adverse effects of anticancer therapyJ Altern Complement Med. 2018;24(9-10):933-941. doi:

  3. Jiang W, Wang L, Zhang J, et al. Effects of postoperative non-steroidal anti-inflammatory drugs on long-term survival and recurrence of patients with non-small cell lung cancerMedicine (Baltimore). 2018;97(39):e12442. doi:10.1097/MD.0000000000012442

  4. Mercadante S, Caraceni A, Masedu F, Scipioni T, Aielli F. Breakthrough cancer pain in patients receiving low doses of opioids for background painOncologist. 2020;25(2):156-160. doi:10.1634/theoncologist.2019-0542

  5. Saito Y, Kobayashi M, Yamada T, et al. Efficacy of additional dexamethasone administration for the attenuation of paclitaxel-associated acute pain syndromeSupport Care Cancer. 2020;28(1):221-227. doi:10.1007/s00520-019-04808-y

  6. Aydın T, Balaban O, Acar A. Ultrasound guided continuous erector spinae plane block for pain management in pulmonary malignancyJ Clin Anesth. 2018;46:63-64. doi:10.1016/j.jclinane.2018.01.023

  7. Gao X, Zhang K, Cao S, et al. Surgical treatment of spinal cord compression caused by metastatic small cell lung cancer: Ten years of experience in a single centerCancer Manag Res. 2020;12:3571-3578. Published 2020 May 19. doi:10.2147/CMAR.S250422