Digestive Health Irritable Bowel Syndrome Nutrition What Are Prebiotics? Health benefits, side effects, and what to look for By Barbara Bolen, PhD Barbara Bolen, PhD Twitter Barbara Bolen, PhD, is a licensed clinical psychologist and health coach. She has written multiple books focused on living with irritable bowel syndrome. Learn about our editorial process Updated on January 18, 2023 Medically reviewed by Robert Burakoff, MD, MPH Medically reviewed by Robert Burakoff, MD, MPH LinkedIn Robert Burakoff, MD, MPH, is board-certified in gastroentrology. He is the vice chair for ambulatory services for the department of medicine at Weill Cornell Medical College in New York. Learn about our Medical Expert Board Print Table of Contents View All Table of Contents Benefits Side Effects Dosage Prebiotic Foods Supplements Prebiotics are specialized plant fibers that stimulate the growth of healthy bacteria in the digestive tract. They mainly consist of fiber or complex carbohydrates that your body cannot digest. You can find prebiotics in foods like garlic and asparagus, as well as prebiotic supplements. By stimulating the growth of bacteria like Lactobacillus and Bifidobacterium, prebiotics may help improve digestion, ease constipation, increase mineral absorption, regulate cholesterol, and strengthen the immune system. Prebiotics differ from probiotics, which are foods or supplements that deliver healthy bacteria directly to your stomach and digestive tract. This article offers an unbiased look at the potential health benefits of prebiotic foods and supplements, as well as the possible side effects and risks. Health Benefits of Prebiotics Prebiotics are components of plant-based foods that cannot be digested. Once eaten, they are degraded in the small intestine by healthy bacteria that grow and thrive on them. These are the "good" bacteria your body needs to digest food and control "bad" bacteria or yeast (like Candida that causes oral thrush). The two main prebiotics important to human health are: Fructo-oligosaccharides found in plants such as onion, chicory, garlic, asparagus, banana, and artichokeGalacto-oligosaccharides found in beans and certain root vegetables There is some evidence that prebiotics may improve digestion, increase calcium absorption, enhance immune function, prevent allergic conditions, lower cholesterol, improve brain function, and even reduce the risk of colon cancer. Evidence and Debate The role of prebiotics in general health is uncertain. Many of the health claims are weakly supported, and it is unclear whether your health can improve simply by increasing your intake of prebiotic-rich foods or supplements. Prebiotics for Digestive Disorders Some researchers suggest that prebiotics may play a role in the treatment of irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Study results to date have been mixed. A 2013 study reported that a higher intake of prebiotics can actually make IBS symptoms worse. This is because many prebiotics are high in carbohydrates known as FODMAPs (fermentable, oligosaccharides, disaccharides, monosaccharides, and polyols). As these carbs break down and ferment, they can add to IBS symptoms such as gas, bloating, and abdominal pain. On the other hand, IBD (Crohn’s disease and ulcerative colitis) is characterized by a lack of healthy gut bacteria. Some studies suggest that prebiotics, particularly fructan-oligosaccharides, can help ease gut inflammation and IBD symptoms. Other studies have suggested that prebiotics may be safe and effective in preventing Clostridium difficile-associated diarrhea, which is commonly associated with antibiotic use or recent hospitalization. Possible Prebiotic Side Effects Most prebiotics can be safely consumed without side effects. If side effects do occur, they are generally mild and may include: BloatingGasAbdominal discomfort These side effects usually ease as your digestive system adapts to the change in the intestinal environment. Dosage Most people can get prebiotics by consuming the recommended daily intake of fiber (between 25 grams and 38 grams per day). Eating whole grains and plenty of fruits and vegetables is often the best way to reach this goal. Many prebiotic supplements provide a dose of around four to five grams per day. If you take a prebiotic supplement, start slowly to see how your body reacts. If gas or bloating occurs, cut the dose in half. What Is Synbiotic Therapy? Synbiotic therapy is the combined use of prebiotics and probiotics. Because probiotics are short-lived, prebiotics can help maintain probiotic levels in the gut. Prebiotic Foods Foods are the best source of prebiotics as they provide good nutrition, including essential minerals, vitamins, and antioxidants. Prebiotic foods include: AsparagusChicory rootFennelGarlicJerusalem artichokeLegumes (including beans, chickpeas, lentils, and soybeans)Nuts (such as cashews and pistachios)Onions, leeks, shallots, scallionsWheat products (such as cereal and bread) Prebiotic Supplements If you are thinking about taking a prebiotic supplement, check the label to ensure it contains fructan-oligosaccharides and/or galacto-oligosaccharides. Before starting treatment, speak with your healthcare provider to ensure that it is safe for you based on your medical conditions and any drugs your take. To ensure purity and safety, opt for supplements certified by the U.S. Pharmacopeia (USP), ConsumerLab, or NSF International. Certification does not mean that the product is effective but indicates that it contains the ingredients on the product label without any contaminants. 7 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Davani-Davari D, Negahdoripour M, Karimzadeh I. Prebiotics: definition, types, sources, mechanisms, and clinical applications. Foods. 2019 Mar;8(3):92. doi:10.3390/foods8030092 Parker EA, Roy T, D'Adamo CR, Wieland LS. Probiotics and gastrointestinal conditions: an overview of evidence from the Cochrane Collaboration. Nutrition. 2018 Jan;45:125–34.e11. doi:10.1016/j.nut.2017.06.024 Whelan K. Mechanisms and effectiveness of prebiotics in modifying the gastrointestinal microbiota for the management of digestive disorders. Proceed Nutrition Soc. 2013;72:288-98. doi:10.1017/S0029665113001262 Rasmussen HE, Hamaker BR. Prebiotics and inflammatory bowel disease. Gastroenterol Clin North Am. 2017 Dec;46(4):783-95. doi:10.1016/j.gtc.2017.08.004 Goldenberg JZ, Ma SS, Saxton JD, Martzen MR, Vandvik PO, Thorlund K, Guyatt GH, Johnston BC. Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database System Rev. 2013;(5):CD006095. doi:10.1002/14651858.CD006095.pub3 Office of Disease Prevention and Health Promotion. Dietary Guidelines for Americans, 2020-2025. Markowiak P, Śliżewska K. Effects of probiotics, prebiotics, and synbiotics on human health. Nutrients. 2017 Sep;9(9):1021. doi:10.3390/nu9091021 Additional Reading Kelly G. Inulin-Type Prebiotics: A Review (Part 2). Alternative Medicine Review 2009 14: 36-56. Scott KP, Antoine JM, Midtvedt T, van Hemert S. Manipulating the gut microbiota to maintain health and treat disease. Microb Ecol Health Dis. 2015 Feb 2;26:25877. doi:10.3402/mehd.v26.25877 Yoo JY, Kim SS. Probiotics and Prebiotics: Present Status and Future Perspectives on Metabolic Disorders. Nutrients. 2016 Mar 18;8(3):173. doi:10.3390/nu8030173 By Barbara Bolen, PhD Barbara Bolen, PhD, is a licensed clinical psychologist and health coach. She has written multiple books focused on living with irritable bowel syndrome. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit