Mental Health Substance Use Disorder & Addiction Signs and Symptoms of Prescription Drug Addiction By Katie Wilkinson, MPH, MCHES Katie Wilkinson, MPH, MCHES As a public health professional with over 10 years of experience, Katie is passionate about informing decision-making that impacts the health and well-being of individuals and communities. Learn about our editorial process Published on December 17, 2021 Medically reviewed by Jenny Sweigard, MD Medically reviewed by Jenny Sweigard, MD LinkedIn Jenny Sweigard, MD, is a board-certified physician involved in patient care, including general medicine and critical care medicine. Learn about our Medical Expert Board Print Table of Contents View All Table of Contents Types Frequent Symptoms Rare Symptoms Complications When to See a Doctor Certain strong medications that are typically only available by prescription can run the risk of addiction if misused. Prescription drug misuse is using a drug in a way that was not intended by the person who prescribed it, or using it without a prescription. Misuse becomes abuse when a person experiences consequences of drug use. This article discusses both frequent and rare signs and symptoms of prescription drug addiction and when to seek medical care. DNY59 / Getty Images Types of Prescription Drug Misuse The most common types of prescription drugs that are misused include: Opioids: These medications are prescribed to manage chronic or severe pain. They include oxycodone, hydrocodone, morphine, fentanyl, and codeine. Central nervous system (CNS) depressants: These are medications used to treat seizures, anxiety, and sleep disorders that include barbituates and benzodiazapenes. Stimulants: This type of medication is used to treat attention deficit hyperactivity disorder (ADHD), narcolepsy, and depression. How the drug is taken can impact the risk of addiction. More specifically, this includes: Taking a high dose of the medicationTaking it over long periods of timeUsing extended release formulas Additionally, some people are at a higher risk of developing an addiction to substances. Risk Factors for Addiction People who have experienced the following may be at an increased risk for addiction:Family history of addictionDrug use at an early ageTrauma or abuseLiving with a mental illnessHaving a more pronounced response to medication (enhanced euphoric feeling)Chronic or severe pain Frequent Signs and Symptoms Addiction to prescription medications can manifest in a number of ways depending on the type of drug abused. In general though, if you are concerned that you may be experiencing addiction, some signs may include: Needing to take more to experience same effect over time (increased tolerance) Using medication to avoid withdrawal symptoms (which can include nausea, depression, insomnia, sweating, shaking, and anxiety) Not being able to stop using despite a desire to stop Prioritizing medication use before other activities and obligations Not doing the activities you used to enjoy Knowingly using medication despite experiencing problems due to its use Noticing similar signs and symptoms may be an indicator of prescription drug abuse and addiction in others. Some additional signs—ranging from behavioral, physical, and social—to look out for may include: If prescribed, running out of medication sooner than expectedDilated or narrowed pupilsLack of motivation or energyChallenges with concentrationSlurred speechChange in appetite and sleepingAnxiety and paranoiaNeglecting relationshipsPoor performance in school or at work Rare Signs and Symptoms High doses and misuse of the most commonly misused prescription medications can result in: Seizures Coma Sudden cardiac arrest Respiratory suppression or arrest (when a person stops breathing) Complications There are a few factors that make prescription drug abuse more complex and potentially life-threatening, including: Use of other medications and drugs: Using other illicit drugs or even over-the-counter medications can interact with the use of prescription medications, sometimes leading to increased blood pressure, slow breathing, or irregular heart rhythms.Age: In general, older adults are prescribed medications for longer periods of time. When paired with changes in the way that their bodies metabolize medications, this could lead to more serious complications with prescription drug abuse.Preexisting health conditions: Having respiratory issues that impact breathing may be especially impacted by abusing prescription medications like opioids. Those with wasting syndrome and other conditions that impair their strength and energy may be especially impacted by opioid abuse. When to See a Doctor If you or someone you know is concerned about prescription drug addiction, seeking support from a healthcare provider can help. Stopping the use of some prescription drugs can result in withdrawal symptoms. In the case of depressant medications in particular, the withdrawal symptoms may even be life-threatening. A provider or care team knowledgeable in addiction treatment can help a person taper down their prescription drug use, manage withdrawal symptoms, and provide behavioral treatment or therapy. Urgent Medical Care If a person who uses experiences a prescription drug overdose, it's considered an emergency. Prescription drug overdoses can be fatal. Overdose Signs and Symptoms If someone is experiencing any of the following signs or symptoms of an overdose, they need emergency medical care: For an opioid drug overdose: Small pupils, shallow breathing, becoming unconscious, choking sounds, cold or clammy skin, or discoloration of lips or nails For CNS depressant drug overdose: Slow or shallow breathing, hypoxia, or coma For stimulant drug overdose: Rapid breathing, confusion, high fever, tremors, restlessness, rapid breathing, seizure, or heart problems (potentially leading to a heart attack) If you or someone you know begins to experience any of these signs of drug overdose, seek immediate medical care by calling 911 or going to the nearest emergency room. Healthcare providers may administer medication that can reverse the overdose for a short time (such as naloxone) and provide other life-saving treatment. Summary Some strong prescription medications are used to treat legitimate health conditions. However, their use can put some people at risk for addiction, depending on how they are used. When prescription medication is abused, it can impact day-to-day life and result in social, physical, and behavioral consequences. Some of these signs and symptoms, particularly physical ones, can vary depending on the prescription medication. Knowing the signs can help identify whether you or someone who know may be experiencing addiction. Healthcare providers can be a source of support for those who wish to seek treatment for addiction. Overdosing on medication requires emergency medical care. A Word From Verywell With the rise of potentially addictive prescription medications, it's essential to take any medications only as directed by a healthcare provider. Talk with your provider about any concerns or history of addiction to reduce your risk, or find alternative treatment methods. If you're worried about a loved one who may be experiencing a prescription drug addiction, knowing the signs can help you approach them with your concern and support them if and when they wish to seek addiction treatment. 12 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Tetrault JM, Butner JL. Non-medical prescription opioid use and prescription opioid use disorder: a review. Yale J Biol Med. 2015;88(3):227-233. Kim U, Kim N. Factors associated with prescription pain reliever misuse: an analysis of statewide data. J Am Pharm Assoc. 2019;59(4):498-505. doi:10.1016/j.japh.2019.03.009 National Institute on Drug Abuse. What classes of prescription drugs are commonly misused? U.S. Department of Labor. Risk factors for opioid misuse, addiction, and overdose. Prevention Solutions: Education Development Center. Preventing prescription drug misuse: overview of factors and strategies. HelpGuide.org. Drug abuse and addiction. Felicilda-Reynaldo R. Recognizing signs of prescription drug abuse and addiction, part I. Medsurg Nursing. 2014;23(6):391-396. National Institute on Drug Abuse. Research report series: prescription drug abuse. National Institute on Drug Abuse. How can prescription drug addiction be treated?. Centers for Disease Control and Prevention. Lifesaving naloxone. National Institute on Drug Abuse. Prescription CNS depressants drug facts. National Institute on Drug Abuse. Drug facts: prescription stimulants. By Katie Wilkinson, MPH, MCHES Katie Wilkinson is a public health professional with more than 10 years of experience supporting the health and well-being of people in the university setting. Her health literacy efforts have spanned many mediums in her professional career: from brochures and handouts to blogs, social media, and web content. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit