Mental Health Neurodevelopmental Disorders Autism Treatment/Therapy Risperdal as a Treatment for Autism By Vincent Iannelli, MD Vincent Iannelli, MD Facebook Vincent Iannelli, MD, is a board-certified pediatrician and fellow of the American Academy of Pediatrics. Dr. Iannelli has cared for children for more than 20 years. Learn about our editorial process Updated on July 13, 2020 Medically reviewed by Claudia Chaves, MD Medically reviewed by Claudia Chaves, MD Claudia Chaves, MD, is board-certified in cerebrovascular disease and neurology with a subspecialty certification in vascular neurology. Learn about our Medical Expert Board Print The FDA approved the use of risperidone or Risperdal orally disintegrating tablets for "the symptomatic treatment of irritability in autistic children and adolescents." As the first FDA-approved drug treatment for behaviors associated with autism, this is likely exciting news for parents. But since Risperdal has already been used off-label for many years to treat children with autism, ADHD, and children who are bipolar, it is not exactly a breakthrough. Still, it is reassuring to know that using Risperdal is safe and effective, according to the FDA, to treat irritability and behavior problems associated with autism, including: AggressionDeliberate self-injuryTemper tantrumsQuickly changing moods Fotostorm / E+ / Getty Images Treatment Many parents are surprised when their child is prescribed Risperdal because it is an atypical antipsychotic medication that was originally approved to treat the symptoms of schizophrenia in adults and manic episodes associated with bipolar disorder. These atypical antipsychotics, including Risperdal, Abilify, Geodon, Clozaril, Zyprexa, and Seroquel, have been shown to improve many behavioral symptoms, including aggressiveness, oppositionality, and hyperactivity, in children with psychiatric problems other than schizophrenia. Side Effects The most common side effects of taking Risperdal include drowsiness, constipation, fatigue, and weight gain. The drowsiness is sometimes a 'good' side effect, as many kids who take Risperdal do not sleep well, which adds to their behavior problems during the day. Ask your healthcare provider about other less common, although more serious side effects, including neuroleptic malignant syndrome, tardive dyskinesia, and hyperglycemia and diabetes. Excessive weight gain can also be a problem for children taking Risperdal and other atypical antipsychotic medications. Taking Risperdal Although medications like Risperdal are usually considered to be strong, they often have a dramatic improvement on the behaviors that they are targeting and many parents find that the benefits of trying them outweigh the possible side effects. If your child and family are impaired by his "symptoms of aggression towards others, deliberate self-injuriousness, temper tantrums, and quickly changing moods," then you might ask your pediatrician if Risperdal might be an option for your child with autism. Keep in mind that it is only approved for autistic children who are between the ages of 5 to 16 years old right now. Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Correia Filho AG, Bodanese R, Silva TL, Alvares JP, Aman M, Rohde LA. Comparison of Risperidone and Methylphenidate for Reducing ADHD Symptoms in Children and Adolescents With Moderate Mental Retardation. J Am Acad Child Adolesc Psychiatry. 2005;44(8):748-55. doi:10.1097/01.chi.0000166986.30592.67 Pfeifer JC, Kowatch RA, Delbello MP. Pharmacotherapy of Bipolar Disorder in Children and Adolescents: Recent Progress. CNS Drugs. 2010;24(7):575-93. doi:10.2165/11533110-000000000-00000 Risperdal Full US Prescribing Information Sheet. Revised October 2006. By Vincent Iannelli, MD Vincent Iannelli, MD, is a board-certified pediatrician and fellow of the American Academy of Pediatrics. Dr. Iannelli has cared for children for more than 20 years. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit