Brain & Nervous System Stroke Septic Embolism Causes, Symptoms, and Diagnosis By Jose Vega MD, PhD Jose Vega MD, PhD Verywell Health's LinkedIn Jose Vega MD, PhD, is a board-certified neurologist and published researcher specializing in stroke. Learn about our editorial process Updated on February 25, 2021 Medically reviewed by Nicholas R. Metrus, MD Medically reviewed by Nicholas R. Metrus, MD Verywell Health's LinkedIn Nicholas R. Metrus, MD, is a board-certified neurologist and neuro-oncologist. He currently serves at the Glasser Brain Tumor Center in Summit, New Jersey. Learn about our Medical Expert Board Print Table of Contents View All Table of Contents Overview Causes Symptoms Diagnosis Treatment Prevention A Word From Verywell If you or a loved one has been diagnosed with septic embolism, you likely have many questions about your condition, including how and why you got it, what to expect, and whether there is any treatment for it. Portra Images / Getty Images Overview Septic embolism is a type of infection inside a blood vessel. This term specifically refers to an infection that started in one part of the body and traveled through blood vessels to reach another part of the body, possibly blocking one or more blood vessels. Typically, septic embolism is a bacterial infection that originates in the heart valves. This may be associated with infective endocarditis, an infection of the heart. An infection in the heart can result in a small blood clot, which may travel to other parts of the body. When a bacterial infection or an infected blood clot travels from the heart to the brain, it can block a blood vessel in the brain, causing a stroke, transient ischemic attack (TIA), cerebral hemorrhage, meningitis, brain abscess, or a mycotic aneurysm. Strokes resulting from a septic embolism are classified as septic strokes, which means infected strokes. Causes There are a number of conditions and infections that can cause septic embolism, including: Infected intravenous (IV) line Implanted devices or catheters in the body Heart valve infection Endocarditis Soft-tissue infection in the body Certain dental procedures Infected deep vein thrombosis (DVT), a blood clot in the veins A weak immune system Periodontal disease There are also some lifestyle factors known to contribute to the risk of septic embolism. Intravenous (IV) drug use, in particular, increases the risk of a harmful infection that can cause endocarditis or septic embolism. Typically, when IV drug use is the cause of septic embolism, it begins when bacteria on the skin enter the body and cause an infection. The infection may develop slowly or could progress rapidly. Infective endocarditis may cause destruction of the valves located in the heart, potentially resulting in complications such as congestive heart failure and recurrent septic embolism. Symptoms There are a number of symptoms of septic embolism, but they tend to be non-specific symptoms along the lines of "feeling lousy." This is one of the reasons it takes a while to reach a diagnosis. If you persistently experience the symptoms of septic embolism, your healthcare provider will do a detailed medical checkup to search for the cause of your symptoms. The following symptoms, broken down by category, can be signs of septic embolism. Neurological symptoms include: HemiparesisFacial droopDouble visionAphasiaVertigoHeadacheSeizuresAltered mental status Non-neurological symptoms include: FeverChillsSharp chest or back painNumbnessShortness of breathSore throatFatiguePersistent coughTenderness in the spleenLightheadednessFaintingInflammation Diagnosis Septic embolism can be difficult to diagnose. Most people with septic embolism have a positive blood culture, meaning bacteria are detected in the blood. A positive blood culture helps direct your treatment if you have septic embolism, because your healthcare provider can identify which bacteria are present, and thus which antibiotic is expected to be most effective. A positive blood culture does not define the location or the cause of the infection. Other diagnostic tests are used to further evaluate septic embolism to locate the area of infection and determine the extent of the infection. Diagnostic Tests Tests for septic embolism include:Complete blood count (CBC)Angiogram (an image of the blood vessels)Magnetic resonance imaging (MRI)Transesophageal echocardiogramElectrocardiogramChest X-raySpinal tap Treatment Treatment for septic embolism includes antibiotics to target the bacteria. However, sometimes antibiotics are not completely effective and, in some cases, surgery is necessary to repair a heart valve damaged by the infection. Prevention Septic embolism cannot always be prevented, but sometimes it can. Some of the preventive measures that can protect against septic embolism include: Maintaining good dental health Avoiding skin infections Avoiding body piercings, which can become infected Avoiding tattoos, which can become infected Prompt medical attention for skin infections Preventive antibiotics before medical or dental procedures A Word From Verywell If you have been diagnosed with an unusual condition such as septic embolism, you might not know where to turn. Use these tips to get the most out of your healthcare provider visits so that you can become an empowered patient as you recover. 6 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Stawicki SP, Firstenberg MS, Lyaker MR, et al. Septic embolism in the intensive care unit. Int J Crit Illn Inj Sci. 2013;3(1):58-63. doi:10.4103/2229-5151.109423 Goswami U, Brenes JA, Punjabi GV, Leclaire MM, Williams DN. Associations and outcomes of septic pulmonary embolism. Open Respir Med J. 2014;8:28-33. doi:10.2174/1874306401408010028 Monroe EJ, Tailor TD, McNeeley MF, Lehnert BE. Needle embolism in intravenous drug abuse. Radiol Case Rep. 2012;7(3):714. doi:10.2484/rcr.v7i3.714 Grecu N, Tiu C, Terecoasa E, Bajenaru O. Endocarditis and stroke. Maedica (Buchar). 2014;9(4):375-81. Chou DW, Wu SL, Chung KM, Han SC, Cheung BM. Septic pulmonary embolism requiring critical care: Clinicoradiological spectrum, causative pathogens and outcomes. Clinics (Sao Paulo). 2016;71(10):562-569. doi:10.6061/clinics/2016(10)02 Dieckmann R, Boone I, Brockmann SO, et al. The risk of bacterial infection after tattooing. Dtsch Arztebl Int. 2016;113(40):665-671. doi:10.3238/arztebl.2016.0665 Additional Reading Zakhari N, Castillo M, Torres C. Unusual cerebral emboli. Neuroimaging Clin N Am. 2016;26(1):147-163. doi:10.1016/j.nic.2015.09.013 By Jose Vega MD, PhD Jose Vega MD, PhD, is a board-certified neurologist and published researcher specializing in stroke. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit