Treatment for Septic Joint Infections

A septic joint occurs when a bacterial infection occurs inside a joint space. A joint is a connection between two bones. Joints include the knee, hip, shoulder, and dozens of joints in the spine. Any joint can become infected, but some are more common than others.

Knee joint inflammation
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Septic joints are most common in infants and young children, immunocompromised patients, and people with joint replacements.

A septic joint is problematic for two reasons:

  • The body has a hard time fighting the infection because of a lack of immune defense within the joints.
  • Joint cartilage can be irreversibly damaged by joint infections.

Signs of a Septic Joint

Diagnosis of a septic joint is typically made by looking for one of a number of different signs of joint infection:

  • Symptoms of the Patient: Common symptoms of infection include fevers, chills, sweats, and joint pain.
  • Restricted Movement of the Joint: Sudden, restricted movement of a joint is a cause for concern, as well as difficulty placing weight on the joint.
  • Swelling of the Joint: Infected joints often feel swollen, warm, and tender. Feeling or seeing a swollen hip or ankle is easier than some joints deep inside the body such as the hip or spine.
  • Abnormal Blood Tests: Blood tests are often abnormal including the white blood cell count (a common sign of infection), the sedimentation rate (ESR) or the C-reactive protein (CRP).
  • Abnormal Imaging Tests: X-rays, ultrasounds, or MRIs may show fluid accumulation within the joint, or inflammation of the surrounding tissues.
  • Fluid sample: The definitive test for a joint infection is to obtain a fluid sample from the joint.

The fluid sample can be obtained at the time of a surgical procedure, but are more often done to confirm infection prior to surgery by inserting a needle into the joint to obtain the fluid sample. The fluid can be analyzed to look for infection or for signs of the infection. The white blood cell count of the fluid sample is typically unusually elevated. However, sometimes this can be abnormal in problems that are not an infection, such as gout or arthritis. The most definitive test is a culture of the fluid where a pathologist grows bacteria from the fluid sample to determine exactly what is causing the infection. In addition to confirming the diagnosis of a septic joint, the culture of the fluid can help your healthcare provider determine the best antibiotics for treatment of the condition.

Treatment of Infection

Septic joints require urgent treatment. Treatment consists of draining the infection out of the joint space, often surgically, along with intravenous antibiotics. Time is essential in the treatment of an infected joint, as leaving pus inside a joint can lead to the rapid deterioration of cartilage of the joint. This is especially concerning in young patients with otherwise healthy joints. In this setting, the risk of long-term problems is high, even with proper treatment.

When an infection is treated surgically, your surgeon will either open up the joint or used instruments to enter inside the joint, circulate fluid to irrigate the joint space. It is impossible to remove every bacteria from an infected joint, but in washing out the bulk of the infection, your body has a chance to fight off the remaining infection with the aid of antibiotics. Sometimes infections are treated with open surgical debridement. This means a surgical incision is made over the joint and your surgeon will look directly inside the joint. Other times, arthroscopic joint irrigation can be performed. In this case, an arthroscope will be inserted into the joint, and fluid can be circulated without making large incisions.

A Word From Verywell

Infection within the joint is a very serious problem that requires urgent treatment. Sometimes identifying an infection can be difficult, but there are laboratory tests can be performed to help determine if you have a joint infection. If a joint infection is diagnosed, typically surgery and intravenous antibiotics will be used to address the problem.

4 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
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  2. Faryna A, Goldenberg K. Joint Fluid. In: Walker HK, Hall WD, Hurst JW, editors. Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd edition. Boston: Butterworths; 1990. Chapter 166.

  3. Long B, Koyfman A, Gottlieb M. Evaluation and Management of Septic Arthritis and its Mimics in the Emergency DepartmentWest J Emerg Med. 2019;20(2):331–341. doi:10.5811/westjem.2018.10.40974

  4. Jiang JJ, Piponov HI, Mass DP, Angeles JG, Shi LL. Septic Arthritis of the Shoulder: A Comparison of Treatment Methods. J Am Acad Orthop Surg. 2017;25(8):e175-e184. doi:10.5435/JAAOS-D-16-00103

By Jonathan Cluett, MD
Jonathan Cluett, MD, is board-certified in orthopedic surgery. He served as assistant team physician to Chivas USA (Major League Soccer) and the United States men's and women's national soccer teams.