What Are the Potential Side Effects Of the Shingles Vaccine?

Shingles (herpes zoster) is caused by the chickenpox virus (varicella-zoster virus or VZV). After you have chickenpox, VZV stays dormant in your body.

If it reactivates later, it causes shingles. The shingles vaccination is the only way to prevent shingles or complications from them.

This article looks at shingles symptoms and complications, who should and shouldn't get the shingles vaccine, and the side effects it may cause.

shingles vaccine side effects

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Shingles Symptoms and Complications

Shingles symptoms comes in two stages: the prodromal stage and the eruptive stage.

Prodromal Stage

Prodromal symptoms include:

  • Fever
  • Chills
  • Nausea
  • Headache
  • Light sensitivity
  • Severe burning, stinging, or shooting pains in one region of your body

The skin in the painful area may look and feel like a sunburn.

Eruptive Stage

About three to five days later, you develop a painful, pimple-like rash in the area where you've had pain. It generally feels prickly when you touch it.

Then the pimples turn into blisters. Your skin may be red and swollen, as well. Some people may only experience mild symptoms but for others, shingles can cause intense pain.

The virus affects your nerves and only strikes the area controlled by a single nerve. Those areas are called dermatomes. Shingles usually won't spread beyond the dermatome.


During an outbreak and after the rash clears up, some people may experience complications. Common ones include:

  • Postherpetic neuralgia (PNH): Damaged nerves cause lingering pain where the rash was. This can be a sharp, deep, burning pain that lasts for three months or longer. PNH is a more common complication.
  • Bacterial skin infections: When shingles blisters pop, bacteria can get in.
  • Eye damage: One branch of the trigeminal nerve goes to the eye. Damage there can lead to eye damage, which can be severe.

If you've had shingles and think you're developing any of these complications, get immediate medical attention.

Who Should Get a Shingles Vaccine?

The Centers for Disease Control and Prevention (CDC) says you should get a shingles vaccine if you:

  • Are an adult aged 50 and older
  • Have never had shingles
  • Have had shingles before (some people can get shingles two or three times, so getting vaccinated is still important)
  • Aren't sure whether you've had chickenpox
  • Have been previously vaccinated with the Zostavax shingles vaccine (it is no longer available in the United States)
  • Are age 19 or older and are (or will be) immunodeficient or immunosuppressed because of disease or therapy

An estimated 99% of Americans born on or before 1980 have had chickenpox, even if they don’t remember having the disease.

Did You Have the Zostavax Vaccine?

If you were vaccinated with Zostavax, ask your healthcare provider about getting the newer Shingrix vaccine.

Who Shouldn't Get a Shingles Vaccine?

The CDC says some people shouldn't get the shingles vaccine. That includes those who:

  • Have ever had a severe allergic reaction to any component of the vaccine or after a dose of Shingrix.
  • Tested negative for VZV immunity (which means you haven't had chickenpox and should get that vaccine instead)
  • Currently have shingles
  • Are pregnant
  • Have a severe or moderate acute illness, such as a respiratory infection

Your healthcare provider can answer any questions you have about whether the vaccine is safe for you.

Shingles isn't generally life-threatening. It can be, though, if your immune system is compromised.

Potential Side Effects

Studies have shown that the shingles vaccine is safe. It's a two-shot series. Some people have temporary side effects afterward.

Common side effects usually last for two or three days. They include:

  • Mild to moderate pain in the injection arm
  • Redness and swelling at the injection site
  • Fatigue
  • Muscle pain
  • Headache
  • Fever and chills
  • Stomach pain
  • Nausea

The vaccine creates a strong shingles defense within your body. As a result, temporary side effects are likely. Side effects are more common in younger people, and might interrupt your normal daily activities for a few days. Some people only react to one dose while others react to both of them.


Shingles comes from the same virus as chickenpox. The shingles vaccine is the only way to prevent it.

The shingles rash can be intensely painful. Some people develop complications, including lingering nerve pain and skin infections.

Most people can be safely vaccinated, barring a severe allergy to the vaccine. Your healthcare provider can advise you, if you have any concerns about safety.

Side effects may make you feel sick (and may interrupt your daily routine) for a few days after being vaccinated.

A Word From Verywell

If you have side effects from the shingles vaccine, the CDC recommends reporting them to the Vaccine Adverse Event Reporting System (VAERS). Or your healthcare provider may file this for you. You can file a report by calling 1-800-822-7967. 

If you have questions or concerns about the vaccine, talk to your healthcare provider about them.

Frequently Asked Questions

  • How often do you need to get the shingles vaccine?

    Shingrix (the shingles vaccine) is a two-dose series. You should get the doses between two and six months apart.

  • How long is shingles contagious?

    Generally shingles is not contagious, but a person with active shingles can spread the virus and give chickenpox to someone who has never had it before when the rash is in the blister phase.

    Most cases of shingles last three to five weeks. Keeping the rash covered can help prevent spreading.

  • Can you get shingles after receiving the vaccine?

    Clinical trials have shown that Shingrix prevents shingles in at least 91% of people 50 and older. That age group is the most at-risk of developing shingles.

  • Who should get the shingles vaccine?

    All healthy adults 50 and older should get the shingles vaccine unless they have contraindications such as a severe allergy or pregnancy. This includes people who:

    • Have previously had shingles
    • Received Zostavax (a shingles vaccine that's now off the market)
    • Don't know if they've had chickenpox
  • How long do shingles vaccine side effects last?

    Shingles vaccine side effects typically last for up to three days. These side effects can include pain at the injection site, fatigue, muscle pain, headache, stomach pain, nausea, fever, or chills.

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10 Sources
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  1. Centers for Disease Control and Prevention. Shingles (herpes zoster). clinical overview.

  2. John AR, Canaday DH. Herpes zoster in the older adult. Infect Dis Clin North Am. 2017;31(4):811-826. doi: 10.1016/j.idc.2017.07.016

  3. Cohen KR, Salbu RL, Frank J, Israel I. Presentation and management of herpes zoster (shingles) in the geriatric population. P T. 2013;38(4):217-227.

  4. National Institutes of Health. Shingles.

  5. Mallick-searle T, Snodgrass B, Brant JM. Postherpetic neuralgia: epidemiology, pathophysiology, and pain management pharmacology. J Multidiscip Healthc. 2016;9:447-454. doi: 10.2147/JMDH.S106340

  6. Johns Hopkins Medicine. Shingles.

  7. Centers for Disease Control and Prevention. Shingles vaccination.

  8. Kim YJ, Lee CN, Lee MS, et al. Recurrence rate of herpes zoster and its risk factors: a population-based cohort studyJ Korean Med Sci. 2018;34(2):e1. Published 2018 Dec 20. doi:10.3346/jkms.2019.34.e1

  9. National Institute on Aging. 5 things you need to know about shingles.

  10. University of Michigan, Michigan Medicine. Common questions about the shingles vaccine.