Side Effects of Librax

Large And Small Intestine model

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Librax is a drug that is used to relax the muscles in the intestines and the bladder. It's one of a type of drugs called benzodiazepines. Librax is a combination of two drugs, chlordiazepoxide and clidinium. It's frequently used to treat irritable bowel syndrome (IBS), diverticulosis, or an infection in the digestive tract. It may also be used, though infrequently, to treat stomach ulcers.

Components of Librax

Chlordiazepoxide, which is one part of Librax, is in a class of drugs called benzodiazepines. Benzodiazepines, sometimes called benzos, are sometimes prescribed to treat tension or anxiety. The clidinium component is an anticholinergic. It relaxes the muscles in the gut and the bladder and prevents spasms. In addition, clidiniuman lowers the production of stomach acid.

Important Things to Know

Librax may have a sedative effect, which means that it may make people tired or drowsy. For that reason, it's often recommended that people not drive when taking it and also avoid alcoholic beverages. This, of course, limits its usefulness as a medication for IBS or other chronic conditions.

People with glaucoma, a bladder obstruction, or an enlarged prostate gland shouldn't use Librax. Because of the benzo part of Librax, people who have had difficulty with drug addiction in the past might not be able to take this drug. Librax also shouldn't be taken along with other medications that affect the central nervous system, such as antidepressants.

After taking Librax for a long time, some people might experience withdrawal symptoms when they stop taking it. For this reason, it's important to taper the use of Librax down slowly, rather than stopping it altogether.

Librax shouldn't be used by pregnant women in the first trimester because it has been associated with an increased risk of birth defects. Even after the first trimester, Librax isn't typically used in pregnant women. Women taking Librax should talk to their doctor if there is a possibility of becoming pregnant. Librax is also not typically recommended for women who are breastfeeding an infant.

Common Side Effects

Check with your doctor if any of the following side effects continue or are bothersome:

  • drowsiness, coordination problems, or confusion
  • dry mouth
  • increased or decreased interest in sex
  • irregular menstrual periods
  • nausea
  • problems starting to urinate
  • skin problems
  • swelling

Always Notify Your Doctor About These Side Effects

  • blurred vision
  • constipation
  • eye pain
  • mental depression
  • rash or hives
  • slow heartbeat, shortness of breath, or trouble breathing
  • sore throat and fever
  • trouble sleeping
  • unusual excitement, nervousness, or irritability
  • yellow eyes or skin

Symptoms of Overdose

  • confusion
  • difficulty urinating
  • drowsiness (severe)
  • dryness of mouth, nose, or throat (severe)
  • fast heartbeat
  • slow reflexes
  • unusual warmth, dryness, and flushing of skin

Other Notes

After you stop using this medicine, check with your doctor if you notice any of the following side effects:

  • convulsions (seizures)
  • muscle cramps
  • nausea or vomiting
  • stomach cramps
  • trembling

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor. This information is meant only as a guideline; always consult a physician or pharmacist for complete information about prescription medications.

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Article Sources
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  1. Librax: uses, dosage, side effects. Drugs.com. Published 2019.

  2. Food and Drug Administration. Librax label. Updated January 2017.

  3. Food and Drug Administration. Librax label. Updated January 2017.

  4. Food and Drug Administration. Librax label. Updated January 2017.

  5. Memorial Sloan Kettering Cancer Center. Clidinium and Chlordiazepoxide. Updated January 8, 2020.

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