Staph Skin Infections and MRSA

Staph is a shorthand way to talk about the Staphylococcus aureus bacteria, which is a common cause of skin infections. Staph can also cause other infections throughout the body. Methicillin-resistant Staphylococcus aureus (MRSA) has become a concern because it does not respond to many antibiotics used for Staph.

Types of Staph Skin Infections

The symptoms of a staph skin infection depend on where the infection is. The staph bacteria can cause:

• Boils: An abscess within the skin, also called a furuncle
• Cellulitis: A localized skin infection which can make the skin red, painful, and warm
• Folliculitis: An infection of hair follicles
• Impetigo: Causes blisters (bullous impetigo) or honey-colored crusted lesions on the skin
• Paronychia: An infection of the skin folds of the nails

In addition to skin infections, staph bacteria can cause:

• Bacteremia: A blood infection
• Deep abscesses: A collection of pus somewhere inside the body
• Endocarditis: An infection of the valves of the heart
• Food poisoning: Typically from toxin-producing Staphylococcus aureus in raw milk and cheese and other high-risk foods
• Lymphadenitis: An infection of a lymph gland, which causes it to be red, swollen, and painful
• Lymphangitis: An infection of the lymph channels that drain to lymph glands, causing red streaks in the skin
• Osteomyelitis: A bone infection
• Scalded skin syndrome: Can lead to blistering skin that appears scalded and peels away
• Septic arthritis: An infection of a joint, like the hip or knee
• Styes: An infection of the glands on the eyelid
• Toxic shock syndrome: Classically associated with tampon use

The Staphylococcus aureus bacteria can also less commonly cause other infections, including pneumonia, ear infections, and sinusitis.

MRSA

MRSA is an acronym for methicillin-resistant Staphylococcus aureus, a type of bacteria that has become resistant to many antibiotics, including methicillin, penicillin, amoxicillin, and cephalosporins. It is routinely pronounced M.R.S.A., not MUR-SA.

Although once limited to hospitals, nursing homes, and other healthcare facilities, MRSA infections are now very common among healthy children and adults in the community. Unfortunately, some staph infections, especially invasive MRSA infections, can be deadly.

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Diagnosis

Talk to your pediatrician if you think that your child might have a staph infection or if you are concerned about MRSA. The diagnosis of most skin infections is made by the pattern of symptoms and physical exam findings.

It is not usually possible to know whether the infection is caused by staph or a bacteria like group A beta-hemolytic streptococcus (Streptococcus pyogenes). In often doesn't matter, as the antibiotic prescribed will likely treat either bacteria.

To make a definitive diagnosis and to confirm that staph is the bacteria causing the infection, a culture can be done. Once a bacteria is identified in a culture, the pattern on sensitivities to antibiotics can help to tell whether or not it is actually MRSA, routine S. aureus, or another bacteria.

Treatment

Antistaphylococcal antibiotics are the usual treatments for staph infections. This may include a topical antibiotic cream (Bactroban, Altabax, etc.) for simple impetigo, warm compresses, and drainage for abscesses, an oral antibiotic, or an intravenous antibiotic for more serious or persistent infections.

Commonly used oral antistaphylococcal antibiotics include the first-generation cephalosporins like Keflex (cephalexin) and cefadroxil.

As resistance to antibiotics is now common among staph bacteria, including MRSA, the first antibiotic prescribed may not work. Many of these community-acquired MRSA infections can still be treated with oral antibiotics, though, such as clindamycin and trimethoprim-sulfamethoxazole (TMP-SMX or Bactrim).

Zyvox (linezolid) is a newer antibiotic used to treat complicated skin and soft tissue infections, including MRSA, in children. It is rather expensive though and is prescribed when other antibiotics either aren't working or the staph bacteria is known to be resistant to other more commonly used antibiotics, such as Bactrim and clindamycin.

Although it can be uncomfortable for your child, having your pediatrician drain an abscess can be the best way to get rid of the infection.

Prevention

Things to know about how staph infections and MRSA spread and may be prevented include:

• The S. aureus bacteria commonly live on or colonizes the skin of children and adults. It is especially common to find it in the nose, which can make it easily spread as children pick their nose.
• MRSA has become more common. It is thought that up to 2% of people are colonized with the MRSA bacteria.
• To get rid of staph colonization, it can sometimes help to treat all family members with mupirocin (Bactroban) nasal gel twice a day for 5-7 days, have everyone take weekly Hibiclens or bleach baths, keep all wounds covered, and encourage very frequent handwashing.
• Keep bites, scrapes, and rashes clean and covered to prevent them from getting infected by the staph bacteria.
• Encourage kids to avoid sharing towels, razors, sports equipment, and other personal items at school and in the locker room, where spreading staph infections seems to be common.