Cancer Breast Cancer Benign Breast Conditions An Overview of Subareolar Nipple Abscess By Mary Nolan-Pleckham, RN Mary Nolan-Pleckham, RN LinkedIn Mary is a freelance nurse writer specializing in making healthcare and medical content accessible for people at all levels of health literacy. Her MSN in nursing education prepared her to deliver accurate and trustworthy medical information that educates and empowers the public. Learn about our editorial process Updated on April 17, 2022 Medically reviewed by Peter Weiss, MD Medically reviewed by Peter Weiss, MD Peter Weiss, MD, is a board-certified OB/GYN and expert in women's health. Learn about our Medical Expert Board Print Table of Contents View All Table of Contents Symptoms Causes Diagnosis Treatment Frequently Asked Questions An abscess is a pocket of pus—a collection of fluid produced by the body’s immune system when fighting an infection. Abscesses can occur anywhere but are commonly found just under the skin. A subareolar nipple abscess is a pocket of pus found on the breast in the nipple or beneath your areola. The areola is the ring of darker (pigmented) skin that circles the nipple. When the immune system fights the infection in the abscess, the area becomes inflamed and often swells. A subareolar nipple abscess may cause pain, a small tender lump, and drainage of pus. Subareolar nipple abscesses occur most commonly in younger or middle-aged women who are not breastfeeding. They have been found in men as well. An abscess occurs when bacteria that normally live on the skin enter the body through a cut, puncture, or another hole in the skin. Several different bacteria may be responsible for causing an abscess. Usually, when the abscess is drained, a sample is sent to the lab to help determine the appropriate antibiotic treatment. This article discusses the symptoms, causes, diagnosis, and treatment of subareolar nipple abscesses. A subareolar nipple abscess can also be referred to as an areolar gland abscess, Zuska's disease, or lactiferous fistula. The Parts of the Outer Breast Symptoms The most common symptoms associated with a subareolar nipple abscess include: A swollen and tender area of tissue on your nipple or areola Pus or discharge emerging from the swollen tissue A fever A general feeling of illness, similar to flu-like symptoms Verywell / Emily Roberts Causes The breasts have glands in the areolas (areolar glands), which are modified sweat glands that open on the skin's surface. Bacteria can sometimes find their way into the glands. For example, bacteria multiply underneath the skin if the areolar glands become blocked. As the bacteria multiply, the immune system is activated to fight the local infection. White blood cells move into the blocked-up areas. Then, pus forms when white blood cells, dead tissue, and bacteria build up in the abscess pocket. Possible risk factors for subareolar abscess include: Smoking Autoimmune disease Infection Trauma Breastfeeding Diabetes Diagnosis Any painful lump under your nipple or areola should be evaluated by your healthcare provider. While the painful lump is most likely to be a benign condition, it may still require treatment. Clinical breast exam, mammogram, breast ultrasound, MRI, and breast biopsy are all used by medical teams to determine the cause of any painful breast lump. Your healthcare provider may recommend further testing depending on what they see on your exam. You may be diagnosed with one of the following: Subareolar abscess is essentially a "walled off" infection in which the body has contained the bacteria in one place by forming walls around the infected area of tissue. Breast ultrasound and fine-needle aspiration (FNA) are often used to diagnose subareolar abscesses. The material drained from the abscess is sent to the lab to identify the infectious bacteria to guide antibiotic medication choices. Mastitis is a generalized inflammation in your breast from a clogged milk duct. There may or may not be an infection (bacteria in the duct) with mastitis. A mastitis infection can sometimes develop into an abscess. Inflammatory breast cancer is a rare form of breast cancer that can also cause blocked ducts and painful swelling/inflammation of the breast tissue. A breast biopsy is the best way to definitively identify cancer. Treatment For any breast abscess, antibiotics are usually recommended along with other treatments. For small abscesses, the treatment of choice is aspiration (drawing out the fluid and pus with a syringe). Aspiration can be done with or without ultrasound guidance. Somewhat larger abscesses—over 3 centimeters (cm) or roughly 1 inch and a half in diameter—may require the placement of a percutaneous catheter. This is a small tube that is inserted through the skin and into the abscess to allow for the continued drainage of any pus that develops. Some abscesses are more difficult to treat, and a surgical incision and drainage (I&D) may need to be done. This might be the case if the abscess is larger than 5 centimeters, multiloculated (has several compartments separated from each other, making them difficult to drain), or has been present for a long time. For persistent severe abscesses, it is sometimes necessary to surgically remove the abscess and the glands in which they occur. However, the abscess may persist or recur in some cases, necessitating further treatment. Antibiotics are needed to resolve the infection associated with an abscess. After your abscess is drained, it is important to finish taking your antibiotics even if your symptoms have resolved. If all the bacteria in the abscess are not killed, your symptoms are more likely to recur. Fortunately, there does not seem to be much indication that these abscesses are a risk factor for developing breast cancer later. However, scarring caused by an abscess can sometimes make mammogram readings more difficult. Treatment in Men Subareolar abscesses in men are very uncommon, but when they occur, it is recommended that they be treated aggressively with complete excision of the duct. In men, breast abscesses are often complicated by fistulas, abnormal passageways between the duct and the skin of the areola. If not completely removed, the abscesses commonly recur. Summary Subareolar nipple abscesses can occur in women or men. They are often painful lumps in the area around the nipple. While they are generally easily drained and treated with antibiotics, there are a few very serious medical conditions with similar symptoms. Be sure to have your breast examined by your healthcare provider if you have any symptoms of a breast abscess. A Word From Verywell Have any painful lump in your nipple or areola area checked by your healthcare provider to ensure it is not a rare form of breast cancer and to get appropriate treatment. If you have had a subareolar nipple abscess drained, be sure it is noted in your medical record so future mammogram results can be interpreted correctly. Frequently Asked Questions What causes a subareolar nipple abscess? A nipple abscess occurs when glands in the areola (around the nipple) become blocked and bacteria are trapped them. The immune system sends white blood cells into the clog to fight the infection. This can lead to pus forming in the abscess pocket. Is a breast abscess serious? A breast abscess can be serious and typically requires antibiotics. In more severe cases, needle aspiration, surgical drainage, a drainage tube, or surgical removal may be required. How do you treat a subareolar abscess at home? You should see your healthcare provider to get a breast abscess properly diagnosed and treated. You can relieve the pain of an abscess at home with a warm compress and over-the-counter (OTC) pain relievers. What antibiotics treat subareolar abscesses? Subareolar abscesses usually require antibiotic treatment for four to seven days. Common antibiotics used to treat breast abscesses include amoxicillin, clindamycin, doxycycline, trimethoprim, nafcillin, or vancomycin. If you are breastfeeding, ensure your healthcare provider is aware so they can choose a different antibiotic if needed. 7 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Kasales CJ, Han B, Smith JS Jr, Chetlen AL, Kaneda HJ, Shereef S. Nonpuerperal mastitis and subareolar abscess of the breast. AJR Am J Roentgenol. 2014;202(2):W133-139. doi:10.2214/AJR.13.10551 Zhang Y, Zhou Y, Mao F, Guan J, Sun Q. Clinical characteristics, classification and surgical treatment of periductal mastitis. J Thorac Dis. 2018;10(4):2420-2427. doi:10.21037/jtd.2018.04.22 Giess CS, Golshan M, Flaherty K, Birdwell RL. Clinical experience with aspiration of breast abscesses based on size and etiology at an academic medical center. J Clin Ultrasound. 2014;42(9):513-521. doi:10.1002/jcu.22191 Fahrni M, Schwarz EI, Stadlmann S, Singer G, Hauser N, Kubik-Huch RA. Breast abscesses: diagnosis, treatment and outcome. Breast Care. 2012;7(1):32-38. doi:10.1159/000336547 Kazama T, Tabei I, Sekine C, et al. Subareolar breast abscess in male patients: a report of two patients with a literature review. Surgical Case Reports. 2017;3(1):128. doi:10.1186/s40792-017-0402-3 Lam E, Chan T, Wiseman S. Breast abscess: evidence-based management recommendations. Expert Review in Anti Infective Therapy. 2014;12(7):753-762. doi:10.1586/14787210.2014.913982 Mount Sinai. Subareolar abscess. Additional Reading Irusen H, Rohwer A, Steyn D, and Young T. Treatments for breast abscesses in breastfeeding women. Cochrane Database of Systematic Reviews. 2015;(8):CD010490. doi:10.1002/14651858.CD010490.pub2 Johnson SP, Kaoutzanis C, Schaub GA. Male Zuska's disease. BMJ Case Reports. 2014;2014:pii: bcr2013201922. doi:10.1136/bcr-2013-201922 MedlinePlus. Subareolar abscess. Originally written by Pam Stephan Pam Stephan Pam Stephan is a breast cancer survivor. Learn about our editorial process See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit