An Overview of Thyroid Disease in Men

Symptoms can vary significantly from women

Thyroid disease in men involves many of the same symptoms as those that affect women with a thyroid disorder. Men, however, may also experience some manifestations of a thyroid issue that are unique to their sex—some of which you may not immediately associate with the condition such as low sperm count, loss of muscle mass, and erectile dysfunction.

Many men don't consider that they could have thyroid disease, even if they present with classic symptoms. Part of the reason for that may be that women are up to 10 times more likely to have thyroid disease than men.


5 Common Misconceptions About Thyroid Disease

Common Symptoms

For the most part, males and females experience similar symptoms when it comes to thyroid disease.


Hashimoto's disease is the most common cause of hypothyroidism (underactive thyroid) in the United States. This autoimmune disorder results in your immune system attacking and destroying your thyroid and it tends to run in families. Studies suggest that as many as four of every thousand men in the United States have hypothyroidism.

General symptoms of hypothyroidism include:

  • Weight gain
  • Coarse, dry skin
  • Fatigue
  • Feeling cold
  • Constipation
  • Depression
  • Joint pain
  • Muscle aches or stiffness
  • Memory problems
  • Hair loss
  • Enlarged thyroid


Graves' disease, another autoimmune thyroid condition, is the most common cause of hyperthyroidism (overactive thyroid). When it's treated, you may eventually experience hypothyroidism.

Graves' disease is relatively uncommon in men, occurring at a rate of around 1 per 10,000. The rate is nearly eight times higher in women.

Common symptoms of hyperthyroidism include:

  • Weight loss
  • Feeling nervous or anxious
  • Faster heartbeat
  • Heart palpitations
  • Sweating
  • Tremor
  • Increased appetite
  • Difficulty sleeping
  • Fatigue
  • Muscle weakness
  • Feeling hot
  • Enlarged thyroid
Sexual Dysfunction and Thyroid Disease in Men and Women
Verywell / Nusha Ashjaee

Symptoms in Men

Men with thyroid dysfunction may have symptoms that are more specific to males. Among them:

  • Balding/hair loss
  • Lower sex drive
  • Decreased testosterone levels
  • Gynecomastia, male breast enlargement (hyperthyroidism)
  • Loss of muscle mass and/or strength

Interestingly, men with hyperthyroidism were found to be at greater risk of hip fractures than women.

Sexual Dysfunction

The thyroid impacts sexual function in both males and females, though it may be more obvious in males. As such, men with thyroid disease may also experience these sexual health-related symptoms:

  • Erectile dysfunction
  • Delayed ejaculation (more common in hypothyroidism)
  • Premature ejaculation (more common in hyperthyroidism)
  • Problems with sperm that can lead to infertility such as lower sperm counts, poorer sperm quality, lower semen volume, and less sperm motility

A 2018 review published in Sexual Medicine Review reported that 59% to 63% of men with hypothyroidism experienced decreased libido, erectile dysfunction, and delayed ejaculation. Among men with hyperthyroidism, 48% to 77% had decreased libido, erectile dysfunction, and premature ejaculation.

These are significant numbers. Thankfully, the review also found that treating the underlying thyroid disease significantly improves sexual dysfunction in both males and females.

The researchers also noted that since many of the patients involved in these studies were under the age of 40, an underlying thyroid condition may be the explanation for sexual dysfunction in younger adults, particularly young men.


Thyroid disease diagnosis is the same no matter your sex. Unfortunately, healthcare providers tend to overlook thyroid symptoms in men since thyroid dysfunction is not nearly as common as it is in women.

Because thyroid disease usually affects men over the age of 40 and many of the symptoms are generalized and vague, healthcare providers will often chalk up to symptoms to erectile dysfunction, weight problems, and age.

If a healthcare provider suspects that you have a thyroid problem, they will discuss your medical history and symptoms with you, perform a physical exam, and order some blood tests to check your thyroid hormone levels.

Thyroid Disease Healthcare Provider Discussion Guide

Get our printable guide for your next healthcare provider's appointment to help you ask the right questions.

Doctor Discussion Guide Man

Imaging Tests

Imaging tests are commonly used to look for signs of thyroid disease, including goiters and thyroid enlargement (hyperplasia). The tools used can differ by whether you have hyperthyroid or hypothyroid disease.

If hyperthyroidism is suspected, you may also have imaging tests such as:

  • Radioactive iodine uptake (RAI-U) test
  • Ultrasound
  • Computed tomography (CT)
  • Magnetic resonance imaging (MRI)

If hypothyroidism is suspected, your healthcare provider may order an ultrasound, but it's unlikely you'll need any other imaging tests unless he or she thinks the hypothyroidism is due to a pituitary or brain issue known as central hypothyroidism.


Treatment of thyroid disease depends on whether you have hypothyroidism or hyperthyroidism.


Treating hyperthyroidism usually begins with taking antithyroid medication. Once your thyroid gets back to functioning normally, you may be able to go off of the medication, at least temporarily, or you may need to be on it long-term.

Other treatment options include radioactive iodine ablation, which destroys your thyroid tissue, and a thyroidectomy, a surgery that removes part or all of your thyroid. Both of these treatments eventually result in hypothyroidism.


Having hypothyroidism means that you'll be taking a thyroid hormone replacement medication, typically Synthroid, Tirosint, or Unithroid (levothyroxine), a synthetic form of T4. This will be a lifelong treatment.

If your symptoms aren't managed on levothyroxine, your healthcare provider may add Cytomel (liothyronine), a synthetic form of T3. Another option is to take desiccated thyroid extract (DTE), a prescription medication that's made from pig thyroid and that contains both T3 and T4.


If you're having difficulties with sexual dysfunction and you've just been diagnosed with thyroid disease, be patient. Treating a thyroid condition drastically improves sexual issues in most people. That said, it can take a while for your thyroid to start functioning normally again.

If you find that you're still having problems with erectile dysfunction, decreased libido, delayed ejaculation, or premature ejaculation even after you've been on treatment for your thyroid, and you're feeling better otherwise, talk to your healthcare provider about other factors that could be causing your issues.

In the event that you've already been diagnosed with a thyroid condition and you're still having difficulties, sexual or otherwise, it's possible that your treatment is insufficient. Talk to your healthcare provider about optimizing your treatment so it's tailored to where your thyroid hormone levels should be for you individually.

Frequently Asked Questions

What does the thyroid do?

The thyroid gland releases two hormones, triiodothyronine (T3) and thyroxine (T4), that help control various functions in your body. These functions include metabolism, muscle control, and mood.

Are there risk factors that increase your chances of having thyroid problems?

Females are more likely to have a thyroid-related disease than males but other factors may increase the risk of thyroid problems. These include a family history of thyroid disease, having an autoimmune condition such as lupus or rheumatoid arthritis, ingesting excessive iodine (in food or medications), age older than 60, and having had a thyroid issue or thyroid cancer in the past.

A Word From Verywell

The key point to remember about thyroid disease is that it's usually, though not always, progressive. Because it can affect multiple organs in your body, it’s important to take note of any and all symptoms you experience. It may be easy to attribute these symptoms to age, but most men can sense when a condition is abnormal or is getting worse.

If you think you have thyroid disease, it's important to seek a diagnosis from a qualified healthcare provider. If you're experiencing sexual or erectile dysfunction, be sure to have a thorough thyroid evaluation if only to rule out thyroid disease as a cause.

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10 Sources
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