Understanding Heart Aging and Reversing Heart Disease

The heart is an amazing muscle that beats around 100,000 times a day. It is essentially a complex pump that is able to adjust blood pressure, flow, and volume in order to provide your body with all the blood it needs. Your heart is constantly adjusting to what you are doing and the state of your body. As you age, your heart adjusts to the needs of an older body. These adjustments come with trade-offs, leaving the heart more vulnerable to disease and other problems.

Illustration of a heart in a male torso
angelhell / Getty Images

Your Heart's Job

Every day your heart must beat more than 100,000 times through more than 60,000 miles (if stretched end-to-end) of blood vessels. Your heart also must adjust the rate and force at which it pumps based on your activity level. As we age, changes in the body require that the heart adjusts how it works. For example, the buildup of fat in the arteries, known as atherosclerosis, causes the heart to work harder to pump all that blood through narrower tubes.

The Aging Heart

Heart disease is a leading cause of death. As we age, our heart compensates for clogged arteries by working harder and raising blood pressure. These changes put the heart at risk and impact our quality of life:

  • Approximatetly 80% of heart disease deaths occur in people who are age 65 or older. 
  • Between the ages of 25 and 80 years pulmonary function and aerobic capacity each decline by 40%
  • In your 20s, the average maximum heart rate is 200 beats per minute, but drops as you get older. The average maximum heart rate for 70-year-olds is 150.
  • Age-related changes in heart rate are seen most in maximal and exercise-induced heart rates with negligible changes in resting heart rate.

Aging Arteries

Arteries take oxygen-rich blood away from the heart and deliver it to the body. As we age, our arteries become stiffer and less flexible. This causes our blood pressure to increase. The heart has to adjust to the increase in blood pressure by pumping harder and changing the timing of its valves. These adjustments leave the heart more vulnerable. To stay young at heart, protect your arteries by:

  • Exercising
  • Controlling your blood pressure
  • Watching your cholesterol

Thickening of the Left Ventricle

Researchers have noted that the wall of the left ventricle of the heart becomes thicker with age. This thickening allows the heart to pump stronger. As our blood vessels age, they become narrower, causing blood pressure to increase. The heart compensates for this by becoming stronger and pumping with more force. The heart may also become larger overall as a result.

Mitral Valve Closes More Slowly

The mitral valve closes more slowly with aging. This is because the rate of blood flow from the left ventricle decreases as it relaxes more slowly. It relaxes more slowly because it grows thicker with age (see above).

Exercise Capacity Shrinks

As the heart ages, it becomes less able to respond rapidly to chemical messages from the brain. Researchers do not know exactly why the heart does not respond as fast to messages to speed up and adjust to increased activity. The result is the body cannot exercise as long or as intensely as before. This shows up as shortness of breath, a sign that oxygen-rich blood is not moving fast enough through the body because the lungs are trying to breathe in more oxygen.

"Sitting" Heart Rate Lowers

The heart rate of an older person while sitting is slower than a younger person (but the same when lying down). It is thought that this slower rate is from a decline in the heart-brain communication because fibrous tissue and fatty deposits have built up on the on nerves connecting the heart and brain. To compensate, the heart increases the volume of blood in circulation by raising the diastolic blood pressure.

The Heart Can't Squeeze as Tightly

Because of the increase in diastolic blood pressure, the heart also stretches larger each beat, giving a stronger pump in order to have a stronger contraction to pump the excess blood volume (called the Frank-Starling mechanism). But because of the greater diastolic pressure, the heart can't squeeze as tightly.

Keep Your Heart Healthy and Reverse Heart Disease

Your heart is only as healthy as your arteries. Work hard to keep your arteries healthy by:

23 Sources
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  1. Shaffer F, McCraty R, Zerr CL. A healthy heart is not a metronome: an integrative review of the heart’s anatomy and heart rate variability. Front Psychol. 2014;0. doi: 10.3389/fpsyg.2014.01040

  2. Harrison ME, Norris ML, Obeid N, Fu M, Weinstangel H, Sampson M. Systematic review of the effects of family meal frequency on psychosocial outcomes in youth. Can Fam Physician. 2015;61(2):e96-106. doi: 10.3389/fcvm.2020.00018

  3. Genders AJ, Frison V, Abramson SR, Barrett EJ. Endothelial cells actively concentrate insulin during its transendothelial transport. Microcirculation. 2013;20(5):434-439. doi: 10.7150/ijbs.7502

  4. Head T, Daunert S, Goldschmidt-Clermont PJ. The aging risk and atherosclerosis: a fresh look at arterial homeostasis. Front Genet. 2017;0. doi:10.3389/fgene.2017.00216

  5. Centers for Disease Control and Prevention. Heart Disease Facts.

  6. American Heart Association. Older Americans & Cardiovascular Diseases.

  7. Roman MA, Rossiter HB, Casaburi R. Exercise, ageing and the lung.Eur Respir J. 2016;48(5):1471-1486. doi:  10.1183/13993003.00347-2016

  8. American Heart Association. Target Heart Rates Chart.

  9. Dai X, Hummel SL, Salazar JB, Taffet GE, Zieman S, Schwartz JB. Cardiovascular physiology in the older adults. J Geriatr Cardiol. 2015;12(3):196-201. doi: 10.11909/j.issn.1671-5411.2015.03.015

  10. Sun Z. Aging, arterial stiffness, and hypertension. Hypertension. 2015;65(2):252-256. doi: 10.1161/HYPERTENSIONAHA.114.03617

  11. Tanaka H. Antiaging effects of aerobic exercise on systemic arteries. Hypertension. 2019;74(2):237-243. doi: 10.1161/HYPERTENSIONAHA.119.13179

  12. Fudim M, Hopley CW, Huang Z, et al. Association of hypertension and arterial blood pressure on limb and cardiovascular outcomes in symptomatic peripheral artery disease: the euclid trial. Circ: Cardiovascular Quality and Outcomes. 2020;13(9):e006512. 10.1161/circoutcomes.120.006512

  13. Bergheanu SC, Bodde MC, Jukema JW. Pathophysiology and treatment of atherosclerosis. Neth Heart J. 2017;25(4):231-242. doi: 10.1007/s12471-017-0959-2

  14. Chen C, Sung KT, Shih SC, et al. Age, gender and load-related influences on left ventricular geometric remodeling, systolic mid-wall function, and nt-probnp in asymptomatic asian population. Talkachova A, ed. PLoS ONE. 2016;11(6):e0156467. doi: 10.1371/journal.pone.0156467

  15. Kohn JC, Lampi MC, Reinhart-King CA. Age-related vascular stiffening: causes and consequences. Front Genet. 2015;0. doi: 10.3389/fgene.2015.00112

  16. Madesis A, Tsakiridis K, Zarogoulidis P, et al. Review of mitral valve insufficiency: repair or replacement. Journal of Thoracic Disease. 2014;6(1). doi: 10.3978/j.issn.2072-1439.2013.10.20

  17. Gorelick PB, Furie KL, Iadecola C, et al. Defining optimal brain health in adults: a presidential advisory from the american heart association/american stroke association. Stroke. 2017;48(10):e284-e303. PMID: 28883125

  18. Zeiher J, Ombrellaro KJ, Perumal N, Keil T, Mensink GBM, Finger JD. Correlates and determinants of cardiorespiratory fitness in adults: a systematic review. Sports Medicine - Open. 2019;5(1):39. doi: 10.1186/s40798-019-0211-2

  19. Ogliari G, Mahinrad S, Stott DJ, et al. Resting heart rate, heart rate variability and functional decline in old age. CMAJ. 2015;187(15):E442-E449. doi: 10.1503/cmaj.150462

  20. Fajemiroye JO, Cunha LC da, Saavedra-Rodríguez R, et al. Aging-induced biological changes and cardiovascular diseases. BioMed Research International. 2018;2018:e7156435. doi: 10.1155/2018/7156435

  21. Chaui-Berlinck JG, Monteiro LHA. Frank-Starling mechanism and short-term adjustment of cardiac flow. Journal of Experimental Biology. Published online January 1, 2017:jeb.167106. doi: 10.1242/jeb.167106

  22. Levine GN, Lange RA, Bairey‐Merz CN, et al. Meditation and cardiovascular risk reduction: a scientific statement from the american heart association. JAHA. 2017;6(10):e002218. doi: 10.1161/JAHA.117.002218

  23. LaRocca TJ, Martens CR, Seals DR. Nutrition and other lifestyle influences on arterial aging. Ageing Res Rev. 2017;39:106-119. doi: 10.1016/j.arr.2016.09.002

Additional Reading
  • National Institute on Aging: Aging Hearts and Arteries.

By Mark Stibich, PhD
Mark Stibich, PhD, FIDSA, is a behavior change expert with experience helping individuals make lasting lifestyle improvements.