Cold & Flu Treatment Over the Counter Facts on Aleve-D Sinus and Cold By Kristina Duda, RN Kristina Duda, RN Facebook LinkedIn Twitter Kristina Duda, BSN, RN, CPN, has been working in healthcare since 2002. She specializes in pediatrics and disease and infection prevention. Learn about our editorial process Updated on February 14, 2022 Medically reviewed by Keri Peterson, MD Medically reviewed by Keri Peterson, MD Facebook LinkedIn Twitter Keri Peterson, MD, is board-certified in internal medicine and operates a private practice, Age Well, in New York City. Learn about our Medical Expert Board Print Aleve Cold and Sinus is now called Aleve-D Sinus and Cold. It is one treatment option when you want a long-lasting medication that will help relieve pain and congestion. It combines a fever reducer/pain reliever with a decongestant to help with these symptoms. It is available behind the pharmacy counter, without a prescription, because it contains pseudoephedrine. Cecile Lavabre / Photographer's Choice / Getty Images Active Ingredients In each caplet: Naproxen sodium 220mg (pain reliever/fever reducer)Pseudoephedrine HCl 120mg, extended release (nasal decongestant) Dosage and Directions Adults and children over 12 years old: 1 caplet every 12 hours, not to exceed 2 caplets in 24 hours Children under 12 years should not take this product unless directed to do so by a healthcare provider. Directions:Swallow whole, do not crush or chew.Drink a full glass of water with each dose. Uses Helps relieve cold and flu symptoms including sinus pressure and pain, minor body aches and pains, headaches, nasal and sinus congestion, and fever. Side Effects Naproxen sodium may cause severe allergic reactions which may include: HivesFacial swellingAsthma or wheezingShock Other adverse effects caused by naproxen can include abdominal pain, constipation, nausea, diarrhea, GI bleeding, perforation, ulcers, headache, or dizziness. Pseudoephedrine can cause: Confusion or nervous feelingHeadachesNausea or vomitingLoss of appetiteAtrial fibrillation or premature ventricular beats (abnormal heart rhythms)High blood pressureShakingRestlessnessInsomnia Warnings Do not use if you have ever had an allergic reaction to any other pain reliever/fever reducer. Do not use if you are now taking a medication known as an MAOI or for two weeks after stopping an MAOI. If you are not sure, contact your healthcare provider or pharmacist before taking this medication. May cause stomach bleeding.Keep out of reach of children. In case of overdose, contact Poison Control or go to an Emergency Room immediately. Ask a Healthcare Provider Before Use If... You consume more than 3 alcoholic beverages a day. It may increase the risk of stomach bleedingYou have heart diseaseYou have high blood pressureYou have thyroid diseaseYou have diabetesYou have trouble urinating due to an enlarged prostate glandYou have had serious side effects from any pain reliever or fever reducerYou are pregnant or breastfeeding. It may cause problems in an unborn child if taken during the third trimester of pregnancy Stop Use and Ask a Healthcare Provider If... An allergic reaction occurs, seek medical attention immediatelyYou get nervous, dizzy or sleeplessYou have nasal congestion that lasts more than 7 daysYour symptoms continue or get worseYou have trouble swallowing or you feel like the caplet is stuck in your throatNew or unexpected symptoms occurYou have stomach pain that begins while taking this product or mild stomach problems that do not go awayYou have a fever that lasts longer than 3 days 2 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. U.S. Food and Drug Administration. NAPROSYN (naproxen) Suspension. U.S. National Library of Medicine. Label: Sudafed. Additional Reading "Aleve D Sinus & Cold". MedScape. "Aleve D" Products. Aleve. Bayer Healthcare LLC. By Kristina Duda, RN Kristina Duda, BSN, RN, CPN, has been working in healthcare since 2002. She specializes in pediatrics and disease and infection prevention. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit