Arthritis Treatment Stopain Topical Pain Reliever Information By Carol Eustice Carol Eustice Facebook Carol Eustice is a writer covering arthritis and chronic illness, who herself has been diagnosed with both rheumatoid arthritis and osteoarthritis. Learn about our editorial process Updated on June 03, 2022 Medically reviewed Verywell Health articles are reviewed by board-certified physicians and healthcare professionals. These medical reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. by David Ozeri, MD Medically reviewed by David Ozeri, MD LinkedIn David Ozeri, MD, is a board-certified rheumatologist from Tel Aviv, Israel specializing in arthritis, autoimmune diseases, and biologic therapies. Learn about our Medical Expert Board Fact checked Verywell Health content is rigorously reviewed by a team of qualified and experienced fact checkers. Fact checkers review articles for factual accuracy, relevance, and timeliness. We rely on the most current and reputable sources, which are cited in the text and listed at the bottom of each article. Content is fact checked after it has been edited and before publication. Learn more. by Nick Blackmer Fact checked by Nick Blackmer LinkedIn Nick Blackmer is a librarian, fact-checker, and researcher with more than 20 years’ experience in consumer-oriented health and wellness content. Learn about our editorial process Print Stopain is one of the topical pain relievers available over the counter (OTC). It stands out with its bright red stop sign logo and the product name of Stopain. STOPAIN With the initial onset of joint pain, some people try to self-treat before consulting a healthcare provider. Typically, they check out what's available in the pain relief section of their local drugstore. There are oral medications, such as Tylenol (acetaminophen), Aleve (naproxen sodium), or Advil (ibuprofen)—and topical treatment options, too. Each of the products is indicated for the relief of pain. It's important for you to understand what's in each product that you are considering and how the product claims to work. A Bit of History Stopain was created by a pharmacist in California and marketed locally in 1991. By 1999, it was presented on the QVC channel. The national exposure allowed it to move into its first retail store, Walgreens, in 2000. And now, it can be found in just about any food and drug store across the U.S. Plus, in 2012 the product became available in Canada. In 2002, DRJ Group (owners of Stopain) selected Troy Manufacturing, Inc. as the sole manufacturer of Stopain. Manufacturing takes place at a plant in Hazleton, Pennsylvania. In 2010, Troy Manufacturing, Inc. bought Stopain from the DRJ Group. Stopain Ingredients According to the Stopain website, the active ingredient in Stopain is menthol, which has analgesic (pain-relieving) properties and is used to temporarily relieve minor pain and stiffness associated with arthritis, muscle aches, strains, and backache. Stopain products also contain peppermint oil, eucalyptus oil, glucosamine, and MSM, which are also said to have analgesic properties. Depending on the individual user, pain relief from Stopain may last several hours. Topical analgesics containing menthol are referred to as counterirritants. The products work by causing a burning or cooling sensation which appears to activate pain receptors in your skin (nociceptors) and then desensitize them. Available Formulations of Stopain Two formulations of Stopain are sold over the counter. Others must be purchased from a healthcare provider's office. The OTC products are: Stopain Extra Strength Continuous SprayStopain Extra Strength Roll-On Both of these products contain menthol (8%). They're intended for use in adults and children 12 years and older. They can be applied as needed, up to four times per day. Stopain Clinical is a line of products that are available only from healthcare providers. You can't buy them online or in retail stores. These products include: Stopain Clinical GelStopain Clinical Roll-OnStopain Clinical 360 Continuous Spray These each contain a stronger concentration of menthol (10%). In addition, there is a product called Stopain Clinical Migraine and Headache. This is a homeopathic topical gel that contains different ingredients than the other Stopain products and is purported to work in a different way. Precautions You should not bandage the affected area tightly after applying Stopain gel, roll-on, or spray. You should not use a heating pad over the area and should not apply the product to open wounds or damaged skin. Avoid getting Stopain in or near your eyes. According to the Stopain website, you should stop application of the product and consult your healthcare provider if your symptoms worsen, if your symptoms persist for more than 7 days while using the product, or if symptoms recur a few days after disappearing. Also, observe the skin for redness, irritation, or development of a rash while using Stopain. Discontinue use if that occurs. Read all directions before using the product. A Word From Verywell There are several different topical pain-relieving products on the market. They are available in creams, ointments, gels, patches and they have different active ingredients. Some of the other products also contain menthol (e.g., Bengay), while others may contain capsaicin (e.g., Zostrix) or a nonsteroidal anti-inflammatory drug (e.g., Voltaren (diclofenac) gel which requires a prescription). Since all topical treatments are not created equal, learn about any product you intend to use. Was this page helpful? Thanks for your feedback! Dealing with chronic inflammation? An anti-inflammatory diet can help. Our free recipe guide shows you the best foods to fight inflammation. Get yours today! Sign Up You're in! Thank you, {{form.email}}, for signing up. There was an error. Please try again. What are your concerns? Other Inaccurate Hard to Understand Submit 0 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Stopain website.