Cancer Lung Cancer Symptoms The Most Common Types of Lung Cancer The types of lung cancer that are common vary by age, sex, and smoking status By Lynne Eldridge, MD facebook Lynne Eldrige, MD, is a lung cancer physician, patient advocate, and award-winning author of "Avoiding Cancer One Day at a Time." Learn about our editorial process Lynne Eldridge, MD Medically reviewed by Medically reviewed by Doru Paul, MD on November 18, 2019 Doru Paul, MD, is board-certified in internal medicine, medical oncology, and hematology. Learn about our Medical Review Board Doru Paul, MD Updated on April 02, 2021 Print Table of Contents View All Table of Contents Lung Cancer Types Men vs. Women Differences Based on Age Smokers vs. Non-Smokers Lung Cancer Types Over Time Gene Profile of Tumors The most common type of lung cancer is non-small cell lung cancer, with small cell lung cancer less common and decreasing in incidence. There are three different types of non-small cell lung cancer, of which lung adenocarcinoma is most common. Yet the types and subtypes of lung cancer can vary based on age, sex, and smoking status. There has also been a change in the common types of lung cancer over time. Talking about types of lung cancer, however, can be misleading. We now know no two lung cancers are alike, and are finding some ways in which they are different. For example, two people with lung adenocarcinoma may have very different treatment options, as well as prognosis, based on the molecular profile of their tumor. Let's look at the types of cancer overall, specific groups, and then the importance of knowing the genetic profile of your tumor before starting treatment. Verywell / Emily Roberts Most Common Lung Cancer Types Overall There are two major types of lung cancer. Non-small cell lung cancer is the most common type of lung cancer overall accounting for roughly 80 percent of lung cancers. Small cell lung cancers are responsible for around 15 percent of lung cancers in the United States. Carcinoid tumors are less common, accounting for 5 percent or less of lung tumors. Non-small cell lung cancers are in turn broken down into 3 types. Lung Adenocarcinoma (Accounting for 50 percent of non-small cell lung cancers) Squamous Cell Carcinoma of the Lungs (Responsible for around 30 percent of non-small cell lung cancers) Large Cell Lung Cancer (Responsible for about 10 percent of non-small cell lung cancers) Lung Cancer Differences in Men vs Women Non-small cell lung cancers are found much more commonly among women. These tumors are also the most common type of lung cancer in men, but men are more likely than women to develop small cell lung cancer. Of non-small cell lung cancers, lung adenocarcinomas occur more frequently in women, while squamous cell and large cell lung cancers are more likely to occur in men. Differences Based on Age Lung adenocarcinoma is the most common type of lung cancer in young adults—accounting for roughly 80 percent of these cancers (small cell lung cancers are very uncommon). Young adults with lung cancer are much more likely to have a genetic predisposition to lung cancer and a higher likelihood of treatable mutations (see below). Carcinoid tumors of the lung tend to be found in younger people than the more common types of lung cancer, and are the most common type of lung tumors found in children. Smokers vs. Non-Smokers In many ways, lung cancer in non-smokers is a different disease than lung cancer in people who smoke, and this includes the most common types of the disease. Both non-small cell and small cell lung cancers are linked with a history of smoking, though small cell lung cancer is associated much more strongly with smoking. Non-small cell lung cancers are the form of lung cancer found more frequently in individuals who have never smoked. Of non-small cell lung cancers, lung adenocarcinoma is the type most likely to be found in non-smokers. Squamous cell carcinoma less common than lung adenocarcinoma overall, but is more common in people who have smoked. Carcinoid tumors do not appear to be associated with smoking, and are found in smokers and non-smokers in a ratio similar to the general population. Change in Lung Cancer Types Over Time There is a theory that the addition of filters to cigarettes in years back may have affected the types of lung cancer found. Cancers such as small cell lung cancer and squamous cell lung cancer tend to occur in or near the largest airways and were more common before the addition of filters to cigarettes. When filters became commonly used in cigarettes, cancers found more in the periphery of the lungs such as lung adenocarcinoma became more common, It's thought that the carcinogens in tobacco smoke were deposited in the large airways before the advent of filters, but are carried much deeper into the lungs with the addition of filters. Differences in Gene Profile of Tumors It's now recommended that anyone with non-small cell lung cancer have molecular profiling or genetic testing. With next generation sequencing there are now many treatable mutations, meaning mutations found in lung tumors for which treatment is available. With lung cancer this includes EGFR, ROS1, ALK, BRAF, MET, RET, and HER2. Tumors that have treatable mutations are more commonly found in young adults, never smokers, and women, though they can be found in almost anyone. A Word From Verywell Non-small cell lung cancer tends to grow more slowly than small cell lung cancer and have a better prognosis.That said, long-term survival from either form of lung cancer is higher when found in the earlier stages of the disease. The U.S. Preventive Services Task Force advises people between 50 and 80 who have at least a 20 pack-year history of smoking and still smoke or have quit within the past 15 years undergo computerized tomography screening every year. The exception: Those who may not be healthy enough overall to tolerate treatment if lung cancer is found. For now it's important to know that anyone with lungs can get lung cancer, and lung cancer in never smokers is the sixth leading cause of cancer-related deaths in the United States. Was this page helpful? Thanks for your feedback! Limiting processed foods and red meats can help ward off cancer risk. These recipes focus on antioxidant-rich foods to better protect you and your loved ones. Sign up and get your guide! Sign Up You're in! Thank you, {{form.email}}, for signing up. There was an error. Please try again. What are your concerns? Other Inaccurate Hard to Understand Submit Article Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. US Preventive Services Task Force. Screening for Lung Cancer: US Preventive Services Task Force Recommendation Statement. JAMA. 2021;325(10):962–970. doi:10.1001/jama.2021.1117 Additional Reading National Cancer Institute. Non-Small Cell Lung Cancer Treatment (PDQ) – Health Professional Version. Updated Jan 29, 2019. National Cancer Institute. Small Cell Lung Cancer Treatment (PDQ) – Health Professional Version. Updated Jul 19, 2018.