Nasal Congestion: Self-Care and Medicine for Stuffy Nose

When to Use Decongestants, Nasal Sprays, and At-Home Treatments

A stuffy nose (also known as nasal or sinus congestion) can be an annoying condition that can linger for days or even weeks. However, there are a number of at-home treatments and medications for stuffy nose that can provide relief.

There are many underlying causes for a stuffy nose, but, contrary to popular belief, the nostrils are not clogged by mucus.

Woman with stuffy nose
grinvalds / Getty Images 

This article explores the causes of a stuffy nose and the various drug and non-drug treatments. It also explains when to call a healthcare provider if the symptoms persist or are a sign of something more serious.

What Causes a Stuffy Nose?

A stuffy nose mainly happens when nasal tissues become inflamed. This is often caused by respiratory infections like the cold and flu or by different types of allergies. It can also be caused by hormonal changes during pregnancy or certain medications, including erectile dysfunction drugs and antihypertensives.

Among adults, structural abnormalities such as a deviated septum, enlarged turbinates, or nasal polyps can cause congestion-like symptoms. These problems may be inherited or the result of an injury, chronic allergies, or chronic sinusitis. Dry air and tobacco smoke can make the stuffiness worse. Nasal congestion can also result from continuous positive airway pressure (CPAP) therapy, a type of treatment for obstructive sleep apnea.

Because infants do not know how to breathe through their mouth, a stuffy nose can become problematic and cause problems with feeding or sleeping. Children also can get a stuffy nose from enlarged adenoids, which sometimes need to be surgically removed.

Over-the-Counter Medications

There are different types of drugs that can treat a stuffy nose, the choice of which varies by the underlying cause.

Oral and Nasal Decongestants

Over-the-counter decongestants work by shrinking blood vessels inside the nose. There are both oral and nasal formulations.

Sudafed (pseudoephedrine) is an oral decongestant used to relieve nasal or sinus congestion caused by the common cold, sinusitis, and respiratory allergies. Do not use Sudafed for longer than three days as it can also lead to rebound congestion.

While Sudafed is available without a prescription, it is kept behind the pharmacy counter and requires an ID to obtain. A similar drug called Sudafed PE (phenylephrine) can be purchased without hindrance but has not proven to be anywhere near as effective as pseudoephedrine.

Nasal decongestant sprays like Afrin (oxymetazoline) also provide short-term relief of a stuffy nose. It should also not be used for longer than three days due to the risk of rebound congestion (sometimes referred to as "nasal spray addiction").

Nasal Steroid Sprays

Longer-term relief may be obtained with nasal steroid sprays like Flonase (fluticasone) or Nasonex (mometasone). Nasal steroids work by reducing inflammation in nasal or sinus tissues and provide rapid relief of congestion from hay fever and nasal polyps.

Because nasal steroids blunt the immune response, overuse of the drug can lead to an increased risk of sinus infections.

Oral Antihistamines

Some medications work better for congestion caused by allergies than for congestion caused by viruses. These include over-the-counter drugs like Allegra (fexofenadine), Claritin (loratadine), Zyrtec (cetirizine), or Benadryl (diphenhydramine).

These drugs are known as antihistamines because they block a chemical produced by the body, called histamine, that is responsible for allergy symptoms.

The Food and Drug Administration (FDA) advises against giving children under 2 any cough and cold remedy containing a decongestant or antihistamine. Doing so may lead to potentially life-threatening side effects like convulsions, rapid heartbeats, and death.

Non-Drug Treatments

Stuffy noses do not always need to be treated with drugs. There are several home-spun remedies and over-the-counter products that may be suitable for treating mild sinus or nasal congestion. These include:

  • Drinking a lot of water
  • Using a cool-mist humidifier
  • Using an over-the-counter saline nasal spray
  • Trying a neti pot
  • Rubbing a menthol gel, like Vicks VapoRub, on your chest (not recommended for small children or infants)
  • Using over-the-counter nasal adhesive strips, like Breathe Right
  • Sucking on a menthol cough drop
  • Using a bulb syringe to remove nasal secretions in infants

When to Call a Healthcare Provider

Most of the time, a stuffy nose will clear up on its own within a week. Nasal congestion that lasts longer may be a sign of a serious sinus infection in need of treatment. You may also want to see a healthcare professional if the symptoms are interfering with sleep or your ability to function normally.

A stuffy nose may require medical attention if:

  • You have a high fever.
  • Your symptoms last longer than two weeks.
  • Your nasal passages are completely blocked.
  • Your skin or lips develop a bluish tinge (called cyanosis).
  • Your breathing rate is very rapid.
  • You have difficulty breathing or catching your breath.


A stuffy nose can be caused by many things, including respiratory infections, allergies, nasal polyps, hormonal changes, certain medications, and environmental factors such as dry air and cigarette smoke.

Depending on the underlying cause, a stuffy nose may be treated with oral or nasal decongestants, nasal steroids sprays, or oral antihistamines. Non-drug options include a neti pot, menthol cough drops, a saline nasal spray, a cool-mist humidifier, and adhesive nasal breathing strips.

See a healthcare provider if a stuffy nose persists for more than two weeks, interferes with your ability to sleep or function normally, or is accompanied by signs of an infection.

Frequently Asked Questions

  • What medicine helps with a runny nose?

    There are plenty of medications that help treat a runny nose, but the right choice depends on its cause. A runny nose caused by allergies can be relieved using an antihistamine like Flonase (fluticasone). First-generation antihistamines such as Benadryl Allergy and Chlor-Trimeton can help with a runny nose caused by a cold. If nasal polyps are the reason for a runny nose, visiting a healthcare provider for prescription medication may be required.

  • Can you get rid of a stuffy nose without medicine?

    Yes, you can get rid of a stuffy nose without medicine. Humidifiers, inhaling steam from a hot shower, and neti pots using distilled water are popular options to relieve a stuffy nose. These options offer short-term relief in clearing sinus congestion, but other treatments like medicine may be needed if the symptoms do not go away.

  • Why do I get a stuffy nose at night?

    You might get a stuffy nose at night by lying down to go to sleep. Lying horizontally can cause mucus to travel up toward your head instead of going down your throat. Similarly, blood flow is also affected by your lying position, and the increased blood flow to the nasal passages may cause inflammation. Addressing these causes can help relieve a stuffy nose; for instance, slightly elevate your head when going to sleep instead of laying perfectly flat. Other treatments may be required depending on the cause of a stuffy nose at night.

  • What are the three types of decongestants?

    Different over-the-counter drugs can help relieve sinus or nasal congestion. They include oral or nasal decongestants, nasal steroid sprays, and oral antihistamines.

7 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. MedlinePlus. Stuffy or runny nose - adult.

  2. Kahraman E, Cil Y, Incesulu A. The effect of nasal obstruction after different nasal surgeries using acoustic rhinometry and nasal obstruction symptom evaluation scaleWorld J Plast Surg. 2016;5(3):236-243.

  3. Inoue A, Chiba S, Matsuura K, Osafune H, Capasso R, Wada K. Nasal function and CPAP complianceAuris Nasus Larynx. 2019;46(4):548-558. doi:10.1016/j.anl.2018.11.006

  4. Calvo-Henriquez C, Branco AM, Lechien JR, et al. What is the relationship between the size of the adenoids and nasal obstruction? A systematic reviewInternational Journal of Pediatric Otorhinolaryngology. 2021;151:110895. doi:10.1016/j.ijporl.2021.110895

  5. Laccourreye O, Werner A, Giroud JP, Couloigner V, Bonfils P, Bondon-Guitton E. Benefits, limits and danger of ephedrine and pseudoephedrine as nasal decongestantsEuropean Annals of Otorhinolaryngology, Head and Neck Diseases. 2015;132(1):31-34. doi:10.1016/j.anorl.2014.11.001

  6. U.S. Food and Drug Administration. Use Caution When Giving Cough and Cold Products to Kids.

  7. U.S. Food and Drug Administration (FDA). Is Rinsing Your Sinuses With Neti Pots Safe?

By Kristin Hayes, RN
Kristin Hayes, RN, is a registered nurse specializing in ear, nose, and throat disorders for both adults and children.