Why Do Gay Men Have an Increased Risk of HIV?

Risk Factors in All Men Who Have Sex With Men (MSM)

In the United States, gay men are affected by HIV more than any other people. While men who have sex with men (MSM), including but not limited to gay men, represent only 2% to 7% of the U.S. population, 70% of all new HIV infections in 2019 were in this group. One-third of these were among Black MSM.

There are many reasons for this and several risk factors unique to MSM that can compound the odds of infection. It is these overlapping risk factors that account for the high rate of HIV among men who have sex with men.

This article takes a closer look at four key factors—biological, sexual, social, and cultural—that place gay men and other MSM at the highest risk of HIV compared to all other groups.

Two men in bed

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Biological Risk Factors

Not all MSM engage in anal sex. However, anal sex is one of the main reasons why MSM have higher rates of HIV.

Anal sex is by far the most efficient means of passing the virus. In fact, people who engage in anal sex are 18 more likely to get HIV than those who have vaginal sex.

One of the main reasons for this is the structure of the rectum itself. Unlike the vagina, which is lined with a dense layer of cells (called epithelial cells) that acts as a barrier, the rectum only has a single column of these cells. Because rectal tissues are fragile, they are also prone to breakage, allowing the virus to slip past this thin layer.

Rectal tissues are also rich in immune cells called CD4 T cells. These are the very cells that HIV targets for infection.

Because of this, HIV can establish an infection quickly. Studies have shown that within an hour of exposure, HIV can breach the body's frontline immune defenses. Within 24 hours, the virus can spread throughout the body.


Anal sex is one of the main reasons why MSM are at higher risk of HIV. Not only is the protective lining of the rectum thinner and more breakable than the vagina, but it is rich in the very immune cells that HIV targets for infection.

Sexual Risk Factors

Sexual practices, exposures, and partners all factor into HIV risk.

Gay and bisexual men can "switch" from being the insertive ("top") partner to the receptive ("bottom") partner and often do depending on the different partners they are with.

The bottom partner is between two and 12 times more likely to get HIV than the top partner. Those differences can all but vanish if a person is sexually versatile (able to switch).

There is also a high rate of sexually transmitted diseases (STDs) among MSM. Having an STD can increase the odds of getting HIV. Some infections, like syphilis, increase the risk by as much as 500%.

Among the reasons for the high rate of STDs, MSM are two to three times more likely to have multiple sex partners than heterosexuals.

MSM between the ages of 18 and 24 are more likely to have sex with a partner five or more years older than them. This matters in terms of their risk because the older someone is, the sexual encounters they are likely to have had.


MSM have higher rates of STDs and are more likely to have multiple sex partners, both of which increase the risk of HIV. Having an older sex partner and engaging in versatile anal sex also influences the risk.

Societal Risk Factors

Society also plays a role in the risk of HIV in MSM, particularly Black and Latinx MSM.

Poverty, racism, high rates of unemployment, distrust in government, and a lack of access to healthcare all contribute to the high rates of HIV in people of color. Add to that the risk factors impacting MSM in general and it becomes clear why this group is disproportionately affected.

According to 2019 data, 76% of people living with HIV In the United States have a household income of less than $20,000 per year. Of these, 39% have no job, while 18% are homeless. People of color account for the lion's share of these numbers.

On top of that, MSM of color generally tend to have sex with their own race. Because of this, they are more likely to get HIV because their sexual networks are smaller and the rate of infection in communities of color is higher than in white communities.

These intersecting risk factors compound an already tough situation. Today, Black MSM in the United States have no less than a 50% lifetime risk of getting HIV, according to a study from the Centers for Disease Control and Prevention (CDC).


Poverty, racism, high rates of employment, and unequal access to health care amplify the risk of HIV in Black and Latinx MSM.

Cultural Risk Factors

People with HIV are frequent targets of stigma—not just because of their HIV status, but sometimes also because of their sexual orientation and race. This an affect their health in a number of ways.

To some people, the high rate of HIV among MSM "confirms" that gay and bisexual people are "promiscuous," "diseased," or "immoral." This can send many MSM into hiding.

Rather than subject themselves to shame or discrimination, some men may avoid HIV testing and treatment until the disease is advanced and harder to manage.

Testing positive may also force them to come out about how they got infected, which they may not want or be ready to do.

If they do get tested and have HIV, isolation and a lack of support—which many already know all too well—can lead to depression, alcohol or drug abuse, sexual risk-taking, and inconsistent treatment and care.

All of this accounts, at least in part, for why one of every six MSM with HIV remains undiagnosed compared to one of every eight heterosexuals with HIV.

Among Black MSM with HIV, who may be particular targets of stigma, racism, and homophobia, only 59% who get treatment remain in care. Among Latinx MSM, these same effects translate to higher rates of injecting drug use, further spreading the disease.


The fear of stigma and homophobia discourage many MSM from seeking HIV testing and treatment. Of those who test positive, isolation and a lack of support can lead to depression, substance abuse, sexual risk-taking, and inconsistent care.


Men who have sex with men (MSM) account for 2% to 7% of the U.S. population but around 70% of all new HIV infections each year. There are numerous factors that place gay and bisexual men at such high risk, including biological vulnerabilities, sexual practices, social and economic inequities, and cultural stigma.

Black and Latinx MSM are especially impacted due to the intersection of these and other risk factors, including racism and homophobia.

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  1. Lieb S, Fallon SJ, Friedman SR, et al. Statewide estimation of racial/ethnic populations of men who have sex with men in the U.SPublic Health Rep. 2011 Jan-Feb;126(1):60-72. doi:10.1177/003335491112600110

  2. Centers for Disease Control and Prevention. HIV and gay and bisexual men: HIV incidence. Updated September 16, 2021.

  3. Centers for Disease Control and Prevention. HIV and African American gay and bisexual men. Updated  September 23, 2021.

  4. Grov C, Rendina HJ, Moody RL, Ventuneac A, Parsons JT. HIV serosorting, status disclosure, and strategic positioning among highly sexually active gay and bisexual nenAIDS Patient Care STDS. 2015;29(10):559–68. doi:10.1089/apc.2015.0126

  5. Baggaley RF, White RG, Boily MC. HIV transmission risk through anal intercourse: systematic review, meta-analysis and implications for HIV preventionInt J Epidemiol. 2010;39(4):1048–63. doi:10.1093/ije/dyq057

  6. Tebit DM, Ndembi N, Weinberg, Quinones-Mateu MD. Mucosal transmission of human immunodeficiency virus. Curr HIV Res. 2012 Jan 1;10(1):3–8.

  7. Anderson JL, Khoury G, Fromentin R, et al. Human immunodeficiency virus (HIV)–infected CCR6+ Rectal CD4+ T cells and HIV persistence on antiretroviral therapyJ Infect Dis. 2020 Mar:221(5):744-55. doi:10.1093/infdis/jiz509

  8. Baggaley RF, Dimitrov D, Owen BN, et al. Heterosexual anal intercourse: a neglected risk factor for HIV?Am J Reprod Immunol. 2013;69 Suppl 1(0 1):95–105. doi:10.1111/aji.12064

  9. HIV.gov. Syphilis and HIV: a dangerous duo affecting gay and bisexual men. December 13, 2012

  10. Glick SN, Morris M, Foxman B, et al. A comparison of sexual behavior patterns among men who have sex with men and heterosexual men and women. J Acquir Immune Defic Syndr. 2012 May 1;60(1):83–90. doi:10.1097/QAI.0b013e318247925e

  11. National Institutes of Health. To end HIV epidemic, we must address health disparities. February 19, 2021.

  12. Centers for Disease Control and Prevention. Communities in crisis: is there a generalized HIV epidemic in impoverished urban areas of the United States? December 11, 2019.

  13. Hess KL, Hu X, Lansky A, Mermin J, Hall HI. Lifetime risk of a diagnosis of HIV infection in the United States. Ann Epidemiol. 2017;27(4):238-243. doi:10.1016/j.annepidem.2017.02.003

  14. Centers for Disease Control and Prevention. Estimated HIV incidence and prevalence in the United States, 2015–2019HIV Surveillance Supp Rep. 2021;26(1):1-81.

  15. Zaller N, Yang C, Operario D, et al. Alcohol and cocaine use among Latino and African American MSM in 6 US cities. J Subst Abuse Treat. 2017 Sep;80:26-32. doi:10.1016/j.jsat.2017.06.003