Xtoro (finafloxacin) for Swimmer's Ear

Medication to Treat Swimmer's Ear

What is Xtoro (finafloxacin) Used For:

Xtoro (finafloxacin) is a medication used to treat acute otitis externa, or more commonly known as swimmer’s ear.

How Does Xtoro (finafloxacin) Work:

The most common bacteria associated with swimmer’s ear is Pseudomonas aeruginosa or Staphylococcus aureus. Xtoro (finafloxacin) treats swimmer’s ear by inhibiting enzymes that are necessary for bacteria’s replication or repair. It belongs to a drug class called fluorquinolones, which contains other common medications such as: Cipro, Levaquin, and Avelox.

How Fast Does Xtoro (finafloxacin) Work:

Xtoro (finafloxacin) was shown to cure 71% of all cases of swimmer’s ear by day 11 after treatment was initiated. Typical resolution of ear pain occurred around 3.5 days after administration of the ear drops. According to the trials around Xtoro, without receiving any therapy, people resolved without therapy only 37 to 50 percent of the time while having resolution of ear pain 5.3 to 6.8 days receiving a placebo medication.

How Should I Store Xtoro (finafloxacin):

Xtoro (finafloxacin) can be stored in the refrigerator or at room temperature (36 to 77 degrees Fahrenheit). This medication should not be frozen.

How is Xtoro (finafloxacin) Taken:

Xtoro (finafloxacin) is an otic medication which means that you administer drops of the medication in your ear. You can place the drops of Xtoro directly in the ear canal or you can place the drops on a wick in the ear canal (like the Otowick). Adult and child dosing is generally the same and typically ordered by your doctor to be taken as follows:

  • 4 drops twice a day for 7 days to the affected ear
  • 8 drops to wick (in affected ear) for first dose, then 4 drops twice a day for 7 more days

Prior to instilling Xtoro in the ear canal, you should warm the solution by holding the container in your hands for 1 to 2 minutes. It is important to warm the solution prior to instilling in the ear canal, as cold solution may cause dizziness. After the solution is sufficiently warmed, shake the container well before instilling the medication into your ear canal.

Lie down with the affected ear up. After instilling the drops into the ear, it is important to stay in the position for 60 seconds to allow enough time for the medication to sufficiently penetrate the ear canal. For more instructions on properly administer ear drops see How to Use Ear Drops Correctly.

Can Xtoro (finafloxacin) Interfere With Other Medications:

There are no known medication interactions with Xtoro (finafloxacin).

Can I take Xtoro (finafloxacin) While I’m Pregnant:

Xtoro (finafloxacin) is a Pregnancy Category C medication. This means that no studies have been performed on pregnant women; however studies in animals showed teratogenic effects. You should avoid this medication unless your physician and you feel that the benefits outweigh the risks. There is inadequate information available regarding whether or not it is safe to breastfeed your baby while taking this medication. You should always discuss with your physician prior to taking this medication if you are pregnant or breastfeeding.

Are There Any Precautions or Side-Effects Associated with Xtoro (finafloxacin):

If you have any prior allergic reactions to any quinolone or fluoroquinolone antibiotics, you should avoid taking Xtoro (finafloxacin). Prolonged use due to resistant bacteria may lead to a yeast or fungal infection. If yeast or fungal infection occurs the medication should be stopped immediately. Always consult your physician if you have any suspicions of another infection.

Side-effects were relatively infrequent during the clinical trials of Xtoro (finafloxacin) and included:

  • Nausea 1%
  • Pruritus 1%
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Article Sources

  • Micromedex. (2014). Finafloxacin. Retrieved on December 29, 2014 from http://www.micrommedxsolutions.com.