Pain Threshold and Tolerance in Fibromyalgia and CFS

Fibromyalgia and chronic fatigue syndrome (CFS) both involve low pain thresholds. Your pain threshold is the point at which a sensation becomes painful. It's not the same thing as tolerance, which is how much you can handle.

A doctor taking the blood pressure of a patient
Katrina Wittkamp / Getty Images

For an example of the pain threshold, think of a dentist drilling in your teeth. It doesn't hurt...until it does! It all depends on when your threshold is reached, and it's different for all of us.

Another real-life example is the blood pressure cuff that nurses wrap around your arm and pump up. At first, there's light pressure. Then the pressure increases and increases. For someone with a high pain threshold, it may never get uncomfortable. For someone with a low threshold, it may start uncomfortable and become quite painful.

Pain Thresholds and Fibromyalgia

Pain thresholds vary from person to person and research suggests that they are abnormally low in fibromyalgia. That's why things that aren't painful to most people can cause pain in those with this condition. The medical term for pain caused by things that don't normally hurt is allodynia.

In fibromyalgia, the pressure pain threshold (the point at which pressure becomes painful) is a common area of focus for researchers. A low-pressure pain threshold is a reason behind the tender-point exam, which is a common diagnostic method for the condition.

Two studies have looked at whether doctors can use a blood pressure cuff as a simple way to identify patients who should be evaluated for fibromyalgia. Both concluded that it's a reasonably accurate way to identify a low pressure-pain threshold.

Fibromyalgia typically involves a low threshold to temperature-related pain, known as thermal allodynia. This results in extreme temperature sensitivity, either to cold, heat, or both.

The threshold may also be low when it comes to mechanical stimulation, which involves something moving across your skin. This often shows up as someone being "sensitive" to things like tags in their shirt. It may make heavier or coarser fabrics feel like sandpaper. A hand placed on the upper arm may not hurt, while lightly rubbing the skin does.

Some research also suggests that low pain thresholds are a part of chronic fatigue syndrome and juvenile chronic fatigue syndrome. At least one study shows that pain thresholds drop following exercise for people with this condition. That response may be part of a key symptom of the diseases, which is called post-exertional malaise.

Threshold vs. Tolerance

The term pain threshold is often confused with (or wrongly used interchangeably with) pain tolerance. These terms are actually quite different.

Pain tolerance is the amount of pain you can take before breaking down. The pain threshold is the point at which pain begins to be felt. Both are entirely subjective.

With pain tolerance, this can mean physically breaking down (passing out, vomiting) or mentally breaking down (crying or screaming uncontrollably).

On the surface, these two concepts can seem similar. However, someone with a low threshold can have a high tolerance and vice versa.

Imagine someone who rarely feels pain (high threshold) but then has a major injury. Because they have little experience dealing with pain, their tolerance might be low. Meanwhile, someone who is in pain all the time (low threshold) may be able to function even at high pain levels if a major injury were to occur.

A person with a low threshold and low tolerance may be severely debilitated anytime they're in pain. Someone with a high threshold and high tolerance, on the other hand, may rarely notice pain.

A Word From Verywell

People with a low pain threshold and/or tolerance can often be harshly judged by others. It's important to realize that they aren't being "weak" or "making a big deal out of nothing." These are simply physiological responses they can't control.

With that said, these levels can and do change over time. In someone with fibromyalgia, it may even be different during flares than it is during remissions when symptom levels are lower.

5 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. Winger A, Kvarstein G, Wyller VB, et al. Pain and pressure pain thresholds in adolescents with chronic fatigue syndrome and healthy controls: a cross-sectional study. BMJ Open. 2014;4(9):e005920. doi:10.1136/bmjopen-2014-005920

  2. Clauw DJ, Arnold LM, Mccarberg BH. The science of fibromyalgia. Mayo Clin Proc. 2011;86(9):907-11. doi:10.4065/mcp.2011.0206

  3. Williams DA, Clauw DJ. Understanding fibromyalgia: lessons from the broader pain research community. J Pain. 2009;10(8):777-91. doi:10.1016/j.jpain.2009.06.001

  4. Vargas A, Vargas A, Hernández-paz R, et al. Sphygmomanometry-evoked allodynia--a simple bedside test indicative of fibromyalgia: a multicenter developmental study. J Clin Rheumatol. 2006;12(6):272-4. doi:10.1097/01.rhu.0000249770.86652.3b

  5. Lima LV, Abner TSS, Sluka KA. Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena. J Physiol (Lond). 2017;595(13):4141-4150. doi:10.1113/JP273355

Additional Reading

By Adrienne Dellwo
Adrienne Dellwo is an experienced journalist who was diagnosed with fibromyalgia and has written extensively on the topic.